Predictive Factors of Spontaneous Reporting of Adverse Drug Reactions among Community Pharmacists.

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  • Additional Information
    • Subject Terms:
    • Author-Supplied Keywords:
      Asia
      Careers
      Drug research and development
      Drug safety
      Economics
      Employment
      Factor analysis
      Geographical locations
      Health care
      Health care providers
      Korea
      Labor economics
      Mathematical and statistical techniques
      Mathematics
      Medical doctors
      Medicine and health sciences
      People and places
      Pharmacists
      Pharmacology
      Physical sciences
      Physicians
      Population groupings
      Professions
      Questionnaires
      Research and analysis methods
      Research Article
      Research design
      Social sciences
      Statistical methods
      Statistics (mathematics)
      Survey research
      Surveys
    • Abstract:
      Purpose: To evaluate the association between spontaneous reporting (SR) and the knowledge, attitude, and needs of community pharmacists (CPs), using a questionnaire following a conceptual model known as the mixed model of knowledge-attitude-practices and the satisfaction of needs. Methods: Self-administered questionnaires were used with a nationwide convenience sample of CPs between September 1, 2014 and November 25, 2014 in Korea. The association between SR and the predictive factors was evaluated using multivariate logistic regression analysis. Results: In total, 1,001 questionnaires were analyzed. The mean age of the respondents and the number of years spent in community pharmacy practice were 45.6 years and 15.3 years, respectively. CPs with experience of SR was 29.4%. Being older than 60 (ORadj, 0.16; 95% CI, 0.06–0.42), having prior experience with adverse drug reactions (ADR) (ORadj, 6.46; 95% CI, 2.46–16.98), having higher specific knowledge of SR (ORadj, 3.58; 95% CI, 1.96–6.56), and having less concern about the obstacles to SR (ORadj, 0.36; 95% CI, 0.23–0.57) were significant contributing factors to SR. The main obstacles to SR included perception of ADRs as ‘not serious ADR’ (77.9%), ‘already well known ADR’ (81.5%), and ‘uncertain about causality’ (73.3%). CPs without reporting experience had greater concerns related to the reporting method and the liability of the pharmacy than those with reporting experience (p<0.05). Conclusions: Findings from our study showed around one in three CPs had ADR reporting experience in Korea, while 87.1% had prior experience with ADR cases. The knowledge of SR, prior experience of ADR, and less concern about the obstacles to SR were contributing factors for reporting levels. [ABSTRACT FROM AUTHOR]
    • Abstract:
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    • Author Affiliations:
      1College of Pharmacy & Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea
      2College of Pharmacy, Chung-Ang University, Seoul, South Korea
      3College of Pharmacy, Suncheon University, Suncheon, Joellanam-do, South Korea
      4Regional Pharmacovigilance Center, Korean Pharmaceutical Association, Seoul, South Korea
    • ISSN:
      1932-6203
    • Accession Number:
      10.1371/journal.pone.0155517
    • Accession Number:
      115419742
  • Citations
    • ABNT:
      YU, Y. M. et al. Predictive Factors of Spontaneous Reporting of Adverse Drug Reactions among Community Pharmacists. PLoS ONE, [s. l.], v. 11, n. 5, p. 1–13, 2016. DOI 10.1371/journal.pone.0155517. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=aph&AN=115419742. Acesso em: 1 jun. 2020.
    • AMA:
      Yu YM, Lee E, Koo BS, et al. Predictive Factors of Spontaneous Reporting of Adverse Drug Reactions among Community Pharmacists. PLoS ONE. 2016;11(5):1-13. doi:10.1371/journal.pone.0155517.
    • APA:
      Yu, Y. M., Lee, E., Koo, B. S., Jeong, K. H., Choi, K. H., Kang, L. K., Lee, M. S., Choi, K. H., Oh, J. M., & Shin, W. G. (2016). Predictive Factors of Spontaneous Reporting of Adverse Drug Reactions among Community Pharmacists. PLoS ONE, 11(5), 1–13. https://doi.org/10.1371/journal.pone.0155517
    • Chicago/Turabian: Author-Date:
      Yu, Yun Mi, Euni Lee, Bon Sun Koo, Kyeong Hye Jeong, Kyung Hee Choi, Lee Kyung Kang, Mo Se Lee, Kwang Hoon Choi, Jung Mi Oh, and Wan Gyoon Shin. 2016. “Predictive Factors of Spontaneous Reporting of Adverse Drug Reactions among Community Pharmacists.” PLoS ONE 11 (5): 1–13. doi:10.1371/journal.pone.0155517.
    • Harvard:
      Yu, Y. M. et al. (2016) ‘Predictive Factors of Spontaneous Reporting of Adverse Drug Reactions among Community Pharmacists’, PLoS ONE, 11(5), pp. 1–13. doi: 10.1371/journal.pone.0155517.
    • Harvard: Australian:
      Yu, YM, Lee, E, Koo, BS, Jeong, KH, Choi, Kyung Hee, Kang, LK, Lee, MS, Choi, Kwang Hoon, Oh, JM & Shin, WG 2016, ‘Predictive Factors of Spontaneous Reporting of Adverse Drug Reactions among Community Pharmacists’, PLoS ONE, vol. 11, no. 5, pp. 1–13, viewed 1 June 2020, .
    • MLA:
      Yu, Yun Mi, et al. “Predictive Factors of Spontaneous Reporting of Adverse Drug Reactions among Community Pharmacists.” PLoS ONE, vol. 11, no. 5, May 2016, pp. 1–13. EBSCOhost, doi:10.1371/journal.pone.0155517.
    • Chicago/Turabian: Humanities:
      Yu, Yun Mi, Euni Lee, Bon Sun Koo, Kyeong Hye Jeong, Kyung Hee Choi, Lee Kyung Kang, Mo Se Lee, Kwang Hoon Choi, Jung Mi Oh, and Wan Gyoon Shin. “Predictive Factors of Spontaneous Reporting of Adverse Drug Reactions among Community Pharmacists.” PLoS ONE 11, no. 5 (May 18, 2016): 1–13. doi:10.1371/journal.pone.0155517.
    • Vancouver/ICMJE:
      Yu YM, Lee E, Koo BS, Jeong KH, Choi KH, Kang LK, et al. Predictive Factors of Spontaneous Reporting of Adverse Drug Reactions among Community Pharmacists. PLoS ONE [Internet]. 2016 May 18 [cited 2020 Jun 1];11(5):1–13. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=aph&AN=115419742