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Impact of the Analytical Approach on the Reliability of MRI-Based Assessment of Hepatic Fat Content.
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- Author(s): Burhans, Maggie S1,2 ; Balu, Niranjan3; Schmidt, Kelsey A1,2; Cromer, Gail1; Utzschneider, Kristina M4,5; Schur, Ellen A5; Holte, Sarah E1; Randolph, Timothy W1; Kratz, Mario1,2,5
- Source:
Current Developments in Nutrition. Dec2020, Vol. 4 Issue 12, p1-8. 8p.- Subject Terms:
- Source:
- Additional Information
- Abstract: MRI is a popular noninvasive method for the assessment of liver fat content. After MRI scan acquisition, there is currently no standardized image analysis procedure for the most accurate estimate of liver fat content. We determined intraindividual reliability of MRI-based liver fat measurement using 10 different MRI slice analysis methods in normal-weight, overweight, and obese individuals who underwent 2 same-day abdominal MRI scans. We also compared the agreement in liver fat content between analytical methods and assessed the variability in fat content across the entire liver. Our results indicate that liver fat content varies across the liver, with some slices averaging 54% lower and others 75% higher fat content than the mean of all slices (gold standard). Our data suggest that the entire liver should be contoured on at least every 10th slice to achieve close agreement with the gold standard. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Current Developments in Nutrition is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Abstract:
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