椎间融合器材料:临床应用的优势与关注热点.

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    • Alternate Title:
      Materials of interbody fusion cage: advantages and focus of clinical application.
    • Abstract:
      BACKGROUND: Interbody fusion cage has become an indispensable implant in spinal surgery. With the development of materials science and 3D printing technology, the application prospects of different materials need to be studied. OBJECTIVE: To analyze in detail and prospect the materials of interbody fusion cage in combination with the latest clinical data and the research and development of new materials. METHODS: The first author searched CNKI, VIP, PubMed, Elsevier and other databases from January 1989 to December 2020 by computer, focusing on the current clinical application of interbody fusion cage materials in spinal surgery with key words of “Interbody fusion cage, Biocompatibility, Orthopedic implants, Spinal surgery, 3D printing interbody fusion cage, Biodegradable materials, PEEK fusion cage, Silicon nitride fusion cage” in English and Chinese. RESULTS AND CONCLUSION: There are a variety of interbody fusion cages, including metal materials, polymer materials, inorganic non-metal materials and composite materials. Currently, PEEK and its composite materials are commonly used in clinic. Other materials have new clinical data. With the development of 3D printing technology and the emergence of new materials for 3D printing, metal porous titanium alloy fusion cage has been highly evaluated in clinic. In addition, the filling materials in the cage hole gradually developed from autogenous bone and allogeneic bone to absorbable artificial bone and recombinant bone morphogenetic protein. [ABSTRACT FROM AUTHOR]
    • Abstract:
      背景:椎间融合器已成为脊柱外科临床上不可或缺的植入物,随着材料科学和3D打印技术的发展,不同材料融合器的应用前景有待考究。 目的:结合目前椎间融合器最新临床数据和新材料的研发,对融合器材料进行详细分析并作出展望。 方法:由第一作者应用计算机检索中国知网、维普、PubMed、Elsevier等数据库1989年1月至2020年12月发表的文献,着重检索现阶段椎 间融合器材料在脊柱外科临床上的应用,中文检索词为“椎间融合器,生物相容性,骨科植入物,脊柱外科,3D打印融合器,可降解材 料,聚醚醚酮融合器,氮化硅融合器”,英文检索词“Interbody fusion cage,Biocompatibility,Orthopedic implants,Spinal surgery,3D printing interbody fusion cage,Biodegradable materials,PEEK fusion cage,Silicon nitride fusion cage”。 结果与结论:椎间融合器材料种类繁多,可分为金属材料、高分子材料、无机非金属材料和复合材料,目前临床常用的是聚醚醚酮及其复 合材料融合器,其他材料也有了新的临床数据。随着3D打印技术的发展及3D打印的新型材料出现,金属多孔钛合金融合器在临床上效果 显著。此外,融合器孔内的填充材料从自体骨和同种异体骨逐渐向可吸收的人工骨和重组骨形态发生蛋白发展。 [ABSTRACT FROM AUTHOR]
    • Abstract:
      Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)