Reliability of Semiautomated Computational Methods for Estimating Tibiofemoral Contact Stress in the Multicenter Osteoarthritis Study.

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  • Additional Information
    • NAICS/Industry Codes:
      621512 Diagnostic Imaging Centers
    • Abstract:
      Recent findings suggest that contact stress is a potent predictor of subsequent symptomatic osteoarthritis development in the knee. However, much larger numbers of knees (likely on the order of hundreds, if not thousands) need to be reliably analyzed to achieve the statistical power necessary to clarify this relationship. This study assessed the reliability of new semiautomated computational methods for estimating contact stress in knees from large population-based cohorts. Ten knees of subjects from the Multicenter Osteoarthritis Study were included. Bone surfaces were manually segmented from sequential 1.0 Tesla magnetic resonance imaging slices by three individuals on two nonconsecutive days. Four individuals then registered the resulting bone surfaces to corresponding bone edges on weight-bearing radiographs, using a semi-automated algorithm. Discrete element analysis methods were used to estimate contact stress distributions for each knee. Segmentation and registration reliabilities (day-today and interrater) for peak and mean medial and lateral tibiofemoral contact stress were assessed with Shrout-Fleiss intraclass correlation coefficients (ICCs). The segmentation and registration steps of the modeling approach were found to have excellent day-to-day (ICC 0.93-0.99) and good inter-rater reliability (0.84-0.97). This approach for estimating compartment-specific tibiofemoral contact stress appears to be sufficiently reliable for use in large population-based cohorts. [ABSTRACT FROM AUTHOR]
    • Abstract:
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    • Author Affiliations:
      1Department of Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IA 52242-1088, USA
      2Department of Biomedical Engineering, University of Iowa, 1402 Seamans Center, Iowa City, IA 52242, USA
      3Department of Epidemiology, University of Iowa, 2181 Westlawn, Iowa City, IA 52242-1088, USA
      4Department of Radiology, University of Iowa, Iowa City, IA 52242-1088, USA
      5Department of Epidemiology and Biostatistics, University of California, San Francisco, 185 Berry Street, Lobby 5, Suite 5700, San Francisco, CA 94107-1762, USA
      6Department of Radiology, University of California, San Francisco, 185 Berry Street, Lobby 5, Suite 5700, San Francisco, CA 94107-1762, USA
    • ISSN:
      1748-670X
    • Accession Number:
      10.1155/2012/767469
    • Accession Number:
      84995805
  • Citations
    • ABNT:
      ANDERSON, D. D. et al. Reliability of Semiautomated Computational Methods for Estimating Tibiofemoral Contact Stress in the Multicenter Osteoarthritis Study. Computational & Mathematical Methods in Medicine, [s. l.], p. 1–8, 2012. DOI 10.1155/2012/767469. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=aph&AN=84995805. Acesso em: 6 jul. 2020.
    • AMA:
      Anderson DD, Segal NA, Kern AM, Nevitt MC, Torner JC, Lynch JA. Reliability of Semiautomated Computational Methods for Estimating Tibiofemoral Contact Stress in the Multicenter Osteoarthritis Study. Computational & Mathematical Methods in Medicine. January 2012:1-8. doi:10.1155/2012/767469.
    • AMA11:
      Anderson DD, Segal NA, Kern AM, Nevitt MC, Torner JC, Lynch JA. Reliability of Semiautomated Computational Methods for Estimating Tibiofemoral Contact Stress in the Multicenter Osteoarthritis Study. Computational & Mathematical Methods in Medicine. Published online January 2012:1-8. doi:10.1155/2012/767469
    • APA:
      Anderson, D. D., Segal, N. A., Kern, A. M., Nevitt, M. C., Torner, J. C., & Lynch, J. A. (2012). Reliability of Semiautomated Computational Methods for Estimating Tibiofemoral Contact Stress in the Multicenter Osteoarthritis Study. Computational & Mathematical Methods in Medicine, 1–8. https://doi.org/10.1155/2012/767469
    • Chicago/Turabian: Author-Date:
      Anderson, Donald D., Neil A. Segal, Andrew M. Kern, Michael C. Nevitt, James C. Torner, and John A. Lynch. 2012. “Reliability of Semiautomated Computational Methods for Estimating Tibiofemoral Contact Stress in the Multicenter Osteoarthritis Study.” Computational & Mathematical Methods in Medicine, January, 1–8. doi:10.1155/2012/767469.
    • Harvard:
      Anderson, D. D. et al. (2012) ‘Reliability of Semiautomated Computational Methods for Estimating Tibiofemoral Contact Stress in the Multicenter Osteoarthritis Study’, Computational & Mathematical Methods in Medicine, pp. 1–8. doi: 10.1155/2012/767469.
    • Harvard: Australian:
      Anderson, DD, Segal, NA, Kern, AM, Nevitt, MC, Torner, JC & Lynch, JA 2012, ‘Reliability of Semiautomated Computational Methods for Estimating Tibiofemoral Contact Stress in the Multicenter Osteoarthritis Study’, Computational & Mathematical Methods in Medicine, pp. 1–8, viewed 6 July 2020, .
    • MLA:
      Anderson, Donald D., et al. “Reliability of Semiautomated Computational Methods for Estimating Tibiofemoral Contact Stress in the Multicenter Osteoarthritis Study.” Computational & Mathematical Methods in Medicine, Jan. 2012, pp. 1–8. EBSCOhost, doi:10.1155/2012/767469.
    • Chicago/Turabian: Humanities:
      Anderson, Donald D., Neil A. Segal, Andrew M. Kern, Michael C. Nevitt, James C. Torner, and John A. Lynch. “Reliability of Semiautomated Computational Methods for Estimating Tibiofemoral Contact Stress in the Multicenter Osteoarthritis Study.” Computational & Mathematical Methods in Medicine, January 2012, 1–8. doi:10.1155/2012/767469.
    • Vancouver/ICMJE:
      Anderson DD, Segal NA, Kern AM, Nevitt MC, Torner JC, Lynch JA. Reliability of Semiautomated Computational Methods for Estimating Tibiofemoral Contact Stress in the Multicenter Osteoarthritis Study. Computational & Mathematical Methods in Medicine [Internet]. 2012 Jan [cited 2020 Jul 6];1–8. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=aph&AN=84995805