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West Ashley Library
9 a.m. - 4 p.m.
Phone: (843) 766-6635
Main Library
9 a.m. - 6 p.m.
Phone: (843) 805-6930
Folly Beach Library
Closed for renovations
Phone: (843) 588-2001
John L. Dart Library
9 a.m. - 6 p.m.
Phone: (843) 722-7550
St. Paul's/Hollywood Library
9 a.m. - 5 p.m.
Phone: (843) 889-3300
Mt. Pleasant Library
9 a.m. – 6 p.m.
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Dorchester Road Library
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Edgar Allan Poe/Sullivan's Island Library
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John's Island Library
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Edisto Library
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Wando Mount Pleasant Library
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9 a.m. - 6 p.m.
Phone: (843) 884-9741
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Echo Doppler Estimation of Pulmonary Capillary Wedge Pressure in Patients with Severe Aortic Stenosis.
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- Author(s): Biner, Simon; Topilsky, Yan; Banai, Shmuel; Steinvil, Arie; Arbel, Yaron; Siegel, Robert James; Beigel, Roy; Keren, Gad; Finkelstein, Ariel
- Source:
Echocardiography. Oct2015, Vol. 32 Issue 10, p1492-1497. 6p. - Source:
- Additional Information
- Subject Terms: HEART failure; AORTIC stenosis; BLOOD pressure; CARDIAC catheterization; CARDIAC output; STATISTICAL correlation; DOPPLER echocardiography; HEART beat; PROSTHETIC heart valves; LONGITUDINAL method; SCIENTIFIC observation; PULMONARY artery; MULTIPLE regression analysis; CONTINUING education units; RETROSPECTIVE studies; DATA analysis software; DESCRIPTIVE statistics; DIAGNOSIS
- Abstract: Background Transcatheter aortic valve replacement ( TAVR) has become a treatment option for patients with severe aortic stenosis ( AS) and high surgical risk. Assessment of symptoms in these patients is challenging because of advanced age, comorbidities, and limited physical activity. Noninvasive quantification of pulmonary capillary wedge pressure ( PCWP) in candidates for TAVR may be helpful for risk stratification. The objective of the study was to create a model for estimation of PCWP by echo Doppler in patients with severe AS. Methods and Results Data from 80 patients with severe AS referred for TAVR were used to develop an echo Doppler model for predicting PCWP. Its performance was evaluated in the test cohort of 33 patients who had invasive and noninvasive evaluation. No single echo Doppler parameter estimated PCWP accurately. In the retrospective analysis, the multilinear regression provided an accurate estimate of PCWP (r2 = 0.74). The model included, in order of importance (all P < 0.05), the ratio of early transmitral velocity (E) to annular velocity (E'), the left ventricular ejection fraction, and the velocity time integral of tricuspid regurgitation signal. In the prospective cohort of patients with severe AS, the model demonstrated good predictive ability of PCWP (r = 0.77, P < 0.01). Conclusion In patients with severe AS, noninvasive estimation of PCWP is possible by integration of two-dimensional, spectral, and tissue Doppler variables. [ABSTRACT FROM AUTHOR]
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