A pilot randomized trial evaluating low-level laser therapy as an alternative treatment to manual lymphatic drainage for breast cancer-related lymphedema.

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  • Additional Information
    • Source:
      Publisher: Oncology Nursing Society Country of Publication: United States NLM ID: 7809033 Publication Model: Print Cited Medium: Internet ISSN: 1538-0688 (Electronic) Linking ISSN: 0190535X NLM ISO Abbreviation: Oncol Nurs Forum Subsets: MEDLINE
    • Publication Information:
      Publication: Pittsburgh, PA : Oncology Nursing Society
      Original Publication: New York, Oncology Nursing Society.
    • Subject Terms:
      Breast Neoplasms/*complications ; Drainage/*methods ; Low-Level Light Therapy/*methods ; Lymphedema/*therapy ; Oncology Nursing/*methods; Aged ; Bandages ; Breast Neoplasms/nursing ; Breast Neoplasms/psychology ; Female ; Humans ; Lymphedema/etiology ; Lymphedema/nursing ; Middle Aged ; Musculoskeletal Manipulations ; Pilot Projects ; Psychological Tests ; Quality of Life ; Treatment Outcome
    • Abstract:
      Purpose/objectives: To examine the impact of advanced practice nurse (APN)-administered low-level laser therapy (LLLT) as both a stand-alone and complementary treatment for arm volume, symptoms, and quality of life (QOL) in women with breast cancer-related lymphedema.
      Design: A three-group, pilot, randomized clinical trial.
      Setting: A private rehabilitation practice in the southeastern United States.
      Sample: 46 breast cancer survivors with treatment-related lymphedema.
      Methods: Patients were screened for eligibility and then randomized to either manual lymphatic drainage (MLD) for 40 minutes, LLLT for 20 minutes, or 20 minutes of MLD followed by 20 minutes of LLLT. Compression bandaging was applied after each treatment. Data were collected pretreatment, daily, weekly, and at the end of treatment.
      Main Research Variables: Independent variables consisted of three types of APN-administered lymphedema treatment. Outcome variables included limb volume, extracellular fluid, psychological and physical symptoms, and QOL.
      Findings: No statistically significant between-group differences were found in volume reduction; however, all groups had clinically and statistically significant reduction in volume. No group differences were noted in psychological and physical symptoms or QOL; however, treatment-related improvements were noted in symptom burden within all groups. Skin improvement was noted in each group that received LLLT.
      Conclusions: LLLT with bandaging may offer a time-saving therapeutic option to conventional MLD. Alternatively, compression bandaging alone could account for the demonstrated volume reduction.
      Implications for Nursing: APNs can effectively treat lymphedema. APNs in private healthcare practices can serve as valuable research collaborators.
      Knowledge Translation: Lasers may provide effective, less burdensome treatment for lymphedema. APNs with lymphedema certification can effectively treat this patient population with the use of LLLT. In addition, bioelectrical impedance and tape measurements can be used to assess lymphedema.
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    • Grant Information:
      UL1 RR024975 United States RR NCRR NIH HHS; UL 1RR024975 United States RR NCRR NIH HHS
    • Publication Date:
      Date Created: 20130628 Date Completed: 20140211 Latest Revision: 20231110
    • Publication Date:
      20240104
    • Accession Number:
      PMC3887507
    • Accession Number:
      10.1188/13.ONF.383-393
    • Accession Number:
      23803270