Comparison of Different Models of Structured Self-Monitoring of Blood Glucose in Type 2 Diabetes.

Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 100889084 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-8593 (Electronic) Linking ISSN: 15209156 NLM ISO Abbreviation: Diabetes Technol Ther Subsets: MEDLINE

Original Publication: Larchmont, NY : Mary Ann Liebert, Inc., c1999-

Patient Compliance*; Blood Glucose Self-Monitoring/*methods ; Diabetes Mellitus, Type 2/*blood ; Hyperglycemia/*prevention & control ; Hypoglycemia/*prevention & control ; Stress, Psychological/*prevention & control; Administration, Oral ; Combined Modality Therapy ; Diabetes Mellitus, Type 2/psychology ; Diabetes Mellitus, Type 2/therapy ; Diet, Diabetic ; Drug Therapy, Combination/adverse effects ; Exercise ; Glycated Hemoglobin A/analysis ; Humans ; Hyperglycemia/diagnosis ; Hyperglycemia/epidemiology ; Hypoglycemia/chemically induced ; Hypoglycemia/diagnosis ; Hypoglycemia/epidemiology ; Hypoglycemic Agents/administration & dosage ; Hypoglycemic Agents/adverse effects ; Hypoglycemic Agents/therapeutic use ; Incidence ; Intention to Treat Analysis ; Meals ; Middle Aged ; Sleep ; Stress, Psychological/epidemiology ; Stress, Psychological/etiology ; Taiwan/epidemiology

Background: The aim of this study is to compare the effectiveness of different models of structured self-monitoring of blood glucose (SMBG) in non-insulin-treated type 2 diabetes.
Subjects and Methods: This was a prospective, three-arm, randomized, 36-week trial. There were 138 participants with a mean age of 58.7 years and glycated hemoglobin A1c (HbA1c) level of 8.72% who were allocated to the following groups: six-pair glucose test of pre- and postprandial blood glucose (BG) per week (n = 43); three-pair glucose test of pre- and postprandial BG per week (n = 39); and seven-point BG testing before and after each meal and at bedtime over a course of 3 days in 1 month (n = 40).
Results: The intention-to-treat analysis revealed that all three groups showed significant reductions in HbA1c levels. Comparisons among the groups revealed that only the seven-point group had a significant greater reduction of HbA1c level compared with the three-pair group (between-group mean difference of -0.86 and -0.80 from baseline to 24 and 36 weeks, respectively). No severe hypoglycemic events were reported. Diabetes distress was slightly higher in the six-pair group.
Conclusions: Our results demonstrated that BG testing at six pairs/week, three pairs/week, and seven points for 3 days/month were all effective in improving glycemic outcome, with greater reduction of HbA1c level in the seven-point for 3 days/month group, without increasing burdensome distress in SMBG.

0 (Glycated Hemoglobin A)
0 (Hypoglycemic Agents)
0 (hemoglobin A1c protein, human)

Date Created: 20160308 Date Completed: 20161213 Latest Revision: 20171116

20220301

10.1089/dia.2015.0082

26950418