Mortality Among Adults With Intellectual Disability in England: Comparisons With the General Population.

Publisher: American Public Health Association Country of Publication: United States NLM ID: 1254074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1541-0048 (Electronic) Linking ISSN: 00900036 NLM ISO Abbreviation: Am J Public Health Subsets: MEDLINE

Publication: Washington, DC : American Public Health Association
Original Publication: New York [etc.]

Intellectual Disability/*mortality; Adolescent ; Adult ; Autism Spectrum Disorder/mortality ; Cause of Death ; Comorbidity ; Down Syndrome/mortality ; England/epidemiology ; Epilepsy/mortality ; Female ; Humans ; Male ; Middle Aged ; Mortality, Premature ; Retrospective Studies ; Risk Factors ; Young Adult

Objectives: To describe mortality among adults with intellectual disability in England in comparison with the general population.
Methods: We conducted a cohort study from 2009 to 2013 using data from 343 general practices. Adults with intellectual disability (n = 16 666; 656 deaths) were compared with age-, gender-, and practice-matched controls (n = 113 562; 1358 deaths).
Results: Adults with intellectual disability had higher mortality rates than controls (hazard ratio [HR] = 3.6; 95% confidence interval [CI] = 3.3, 3.9). This risk remained high after adjustment for comorbidity, smoking, and deprivation (HR = 3.1; 95% CI = 2.7, 3.4); it was even higher among adults with intellectual disability and Down syndrome or epilepsy. A total of 37.0% of all deaths among adults with intellectual disability were classified as being amenable to health care intervention, compared with 22.5% in the general population (HR = 5.9; 95% CI = 5.1, 6.8).
Conclusions: Mortality among adults with intellectual disability is markedly elevated in comparison with the general population, with more than a third of deaths potentially amenable to health care interventions. This mortality disparity suggests the need to improve access to, and quality of, health care among people with intellectual disability.

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12/64/154 United Kingdom DH_ Department of Health

Date Created: 20160617 Date Completed: 20170608 Latest Revision: 20220331

20240104

PMC4940652

10.2105/AJPH.2016.303240

27310347