Ethical Considerations in Conducting Pragmatic Trials in Oncology.

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  • Author(s): Hammer MJ;Hammer MJ
  • Source:
    Oncology nursing forum [Oncol Nurs Forum] 2017 Sep 01; Vol. 44 (5), pp. 537-539.
  • Publication Type:
    Comparative Study; Journal Article
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Oncology Nursing Society Country of Publication: United States NLM ID: 7809033 Publication Model: Print Cited Medium: Internet ISSN: 1538-0688 (Electronic) Linking ISSN: 0190535X NLM ISO Abbreviation: Oncol Nurs Forum Subsets: MEDLINE
    • Publication Information:
      Publication: Pittsburgh, PA : Oncology Nursing Society
      Original Publication: New York, Oncology Nursing Society.
    • Subject Terms:
      Morals*; Informed Consent/*ethics ; Medical Oncology/*ethics ; Pragmatic Clinical Trials as Topic/*ethics; Humans ; Research Design
    • Abstract:
      Pragmatic trials evaluate interventions in real-life scenarios, which differ from explanatory trials that control for numerous factors and variables to best determine causal associations. Each approach has advantages and disadvantages. Conducting pragmatic research trials while maintaining the tenets of the ethical conduct of research can sometimes be challenging, particularly regarding informed consent. In this column, distinctions between pragmatic and explanatory trials are discussed from an ethical view.
    • Contributed Indexing:
      Keywords: ethics; pragmatic and explanatory 
trials; research
    • Publication Date:
      Date Created: 20170819 Date Completed: 20180611 Latest Revision: 20190612
    • Publication Date:
      20240105
    • Accession Number:
      10.1188/17.ONF.537-539
    • Accession Number:
      28820523