Intestinal macrophages in mucosal immunity and their role in systemic lupus erythematosus disease.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read Online Read More Add to Saved list
  • Additional Information
    • Source:
      Publisher: SAGE Publications Country of Publication: England NLM ID: 9204265 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-0962 (Electronic) Linking ISSN: 09612033 NLM ISO Abbreviation: Lupus Subsets: MEDLINE
    • Publication Information:
      Publication: London : SAGE Publications
      Original Publication: Houndmills, Basingstoke, Hampshire, UK : Scientific & Medical Division, Macmillan Press Ltd., c1991-
    • Subject Terms:
      Immunity, Mucosal*; Lupus Erythematosus, Systemic/*immunology ; Macrophages/*immunology; Animals ; Cytokines/immunology ; Humans ; Immunity, Innate ; Mice ; Monocytes/immunology ; Sex Factors
    • Abstract:
      Monocytes play an important role in inducing host systemic immunity against invading pathogens and inflammatory responses. After activation, monocytes migrate to tissue sites, where they initiate both innate and adaptive immune responses, and become macrophages. Although mucosal macrophages produce inflammatory cytokines in response to pathogens, the perturbations in innate immune signaling pathway have been implicated in autoimmune diseases such as systemic lupus erythematosus (SLE). In this review, we focus on the role of human macrophages in intestinal innate immune responses, homeostasis, and SLE disease. We further discuss sex differences in the intestinal macrophages and their role in the physiology and pathogenesis of SLE.
    • References:
      Biochem Biophys Res Commun. 1999 Aug 2;261(2):521-7. (PMID: 10425218)
      Nat Immunol. 2001 Aug;2(8):675-80. (PMID: 11477402)
      Eur J Obstet Gynecol Reprod Biol. 2002 Mar 10;101(2):129-34. (PMID: 11858886)
      Nat Rev Immunol. 2001 Nov;1(2):135-45. (PMID: 11905821)
      J Immunol. 2002 Apr 1;168(7):3536-42. (PMID: 11907116)
      Ann Rheum Dis. 2003 Apr;62(4):341-6. (PMID: 12634234)
      Rheumatology (Oxford). 2004 May;43(5):547-54. (PMID: 14747618)
      Histochem Cell Biol. 2004 May;121(5):399-405. (PMID: 15138841)
      Arthritis Rheum. 2004 Jun;50(6):1967-75. (PMID: 15188374)
      Immunol Lett. 2005 Feb 15;97(1):107-13. (PMID: 15626482)
      J Clin Invest. 2005 Jan;115(1):66-75. (PMID: 15630445)
      J Immunol. 2006 Aug 15;177(4):2088-96. (PMID: 16887967)
      Ann N Y Acad Sci. 2006 Nov;1089:218-27. (PMID: 17261769)
      Nat Immunol. 2007 Oct;8(10):1086-94. (PMID: 17873879)
      Mol Cell Endocrinol. 2007 Dec 15;279(1-2):16-25. (PMID: 17923257)
      Immunol Rev. 2007 Dec;220:251-69. (PMID: 17979852)
      Am J Pathol. 2008 Sep;173(3):600-9. (PMID: 18688037)
      Immunol Invest. 2008;37(5):631-44. (PMID: 18716941)
      Curr Opin Immunol. 2008 Dec;20(6):669-75. (PMID: 18852045)
      Nat Rev Immunol. 2008 Dec;8(12):958-69. (PMID: 19029990)
      Cytometry B Clin Cytom. 2009 Jul;76(4):261-70. (PMID: 19199277)
      J Infect Dis. 2009 Apr 15;199(8):1177-85. (PMID: 19265479)
      J Allergy Clin Immunol. 2009 Jul;124(1):3-20; quiz 21-2. (PMID: 19560575)
      Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12061-6. (PMID: 19574451)
      Nat Med. 2009 Aug;15(8):955-9. (PMID: 19597505)
      Am J Pathol. 2009 Nov;175(5):2023-33. (PMID: 19808647)
      Science. 2010 Feb 5;327(5966):656-61. (PMID: 20133564)
      J Immunol. 2010 Jul 15;185(2):1169-76. (PMID: 20554954)
      Nature. 2010 Jun 17;465(7300):937-41. (PMID: 20559388)
      Arch Immunol Ther Exp (Warsz). 2010 Oct;58(5):355-64. (PMID: 20676786)
      Immunity. 2010 Sep 24;33(3):375-86. (PMID: 20832340)
      Am J Physiol Gastrointest Liver Physiol. 2011 Apr;300(4):G621-6. (PMID: 21252046)
      J Autoimmun. 2012 May;38(2-3):J282-91. (PMID: 22225601)
      J Immunol. 2012 Apr 15;188(8):3716-23. (PMID: 22422887)
      Nat Immunol. 2012 Mar 19;13(4):325-32. (PMID: 22430785)
      Blood. 2012 Nov 29;120(23):4599-608. (PMID: 23065151)
      Immunity. 2012 Dec 14;37(6):1076-90. (PMID: 23219392)
      Scand J Immunol. 2013 Mar;77(3):200-12. (PMID: 23298254)
      Nat Immunol. 2013 Oct;14(10):986-95. (PMID: 24048120)
      Clin Immunol. 2014 Mar;151(1):66-77. (PMID: 24525049)
      Nat Rev Immunol. 2014 Jun;14(6):392-404. (PMID: 24854589)
      Immunol Rev. 2014 Jul;260(1):102-17. (PMID: 24942685)
      Cell Mol Immunol. 2015 Jul;12(4):435-43. (PMID: 25109683)
      Rheumatology (Oxford). 2015 Feb;54(2):324-31. (PMID: 25161312)
      MBio. 2014 Sep 30;5(5):e01548-14. (PMID: 25271284)
      PLoS One. 2014 Dec 08;9(12):e114589. (PMID: 25485543)
      Clin Exp Immunol. 2015 Jun;180(3):393-407. (PMID: 25603723)
      Ann Intern Med. 2015 Aug 4;163(3):232-3. (PMID: 26099038)
      Front Immunol. 2015 Nov 30;6:608. (PMID: 26648937)
      Blood. 1993 Nov 15;82(10):3170-6. (PMID: 7693040)
    • Grant Information:
      R01 AI091526 United States AI NIAID NIH HHS; I01 BX000470 United States BX BLRD VA; I01 CX001211 United States CX CSRD VA; UL1 RR029882 United States RR NCRR NIH HHS; P60 AR062755 United States AR NIAMS NIH HHS
    • Contributed Indexing:
      Keywords: Intestine; macrophages; mucosal immunity; systemic lupus erythematosus disease
    • Accession Number:
      0 (Cytokines)
    • Publication Date:
      Date Created: 20180919 Date Completed: 20190103 Latest Revision: 20210228
    • Publication Date:
      20240105
    • Accession Number:
      PMC6398158
    • Accession Number:
      10.1177/0961203318797417
    • Accession Number:
      30223707