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Psoriasis as a Predictor of Cardiometabolic Comorbidity in Women: A Study Based on the Danish National Birth Cohort.
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- Author(s): Blegvad C;Blegvad C; Nybo Andersen AM; Adam A; Zachariae C; Skov L
- Source:
Acta dermato-venereologica [Acta Derm Venereol] 2019 Mar 01; Vol. 99 (3), pp. 274-278.- Publication Type:
Journal Article- Language:
English - Source:
- Additional Information
- Source: Publisher: Society for the Publication of Acta Dermato-Venereologica Country of Publication: Sweden NLM ID: 0370310 Publication Model: Print Cited Medium: Internet ISSN: 1651-2057 (Electronic) Linking ISSN: 00015555 NLM ISO Abbreviation: Acta Derm Venereol Subsets: MEDLINE
- Publication Information: Publication: 2006- : Uppsala: Society for the Publication of Acta Dermato-Venereologica
Original Publication: Stockholm : Acta dermato-venereologica - Subject Terms: Metabolic Syndrome/*epidemiology ; Psoriasis/*epidemiology; Adult ; Body Mass Index ; Comorbidity ; Denmark/epidemiology ; Female ; Humans ; Hypercholesterolemia/epidemiology ; Hyperglycemia/epidemiology ; Hypertension/epidemiology ; Metabolic Syndrome/diagnosis ; Metabolic Syndrome/mortality ; Obesity/epidemiology ; Pregnancy ; Psoriasis/diagnosis ; Psoriasis/mortality ; Risk Assessment ; Risk Factors ; Sex Factors ; Smoking/adverse effects ; Smoking/epidemiology ; Time Factors
- Abstract: Psoriasis is associated with cardiometabolic comorbidity; however, whether this is due to common lifestyle-related risk factors is unclear. This study investigated the association between psoriasis and cardiometabolic comorbidity, taking body mass index and smoking into account. The population comprised expectant mothers in the Danish National Birth Cohort (established 1996-2002). During pregnancy, the women were asked about physician-diagnosed psoriasis. Any association with self-reported cardiometabolic comorbidity 11 years later was assessed using logistic regression. The cohort was also followed up for hospital-diagnosed comorbidity, including cardiac death, until 31 December 2014, and the risk was assessed using Cox regression. A total of 2,435 women with psoriasis (2.90%) and 81,388 women without were identified. Psoriasis was significantly associated with self-reported hypercholesterolaemia (adjusted odds ratio 1.31; 1.01-1.70) and hospital-diagnosed hypertension (adjusted hazard ratio 1.33; 1.08-1.65). Women with psoriasis have an increased risk of developing cardiometabolic comorbidity in early adult life.
- Contributed Indexing: Keywords: cardiometabolic disease; cardiovascular disease; comorbidity; metabolic disease; risk factor; psoriasis
- Publication Date: Date Created: 20181122 Date Completed: 20190618 Latest Revision: 20190618
- Publication Date: 20240105
- Accession Number: 10.2340/00015555-3090
- Accession Number: 30460370
- Source:
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