Evaluating non-medical prescription opioid demand using commodity purchase tasks: test-retest reliability and incremental validity.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read Online Read More Add to Saved list
  • Additional Information
    • Source:
      Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7608025 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2072 (Electronic) Linking ISSN: 00333158 NLM ISO Abbreviation: Psychopharmacology (Berl) Subsets: MEDLINE
    • Publication Information:
      Original Publication: Berlin, New York, Springer-Verlag.
    • Subject Terms:
      Commodification* ; Economics, Behavioral*; Analgesics, Opioid/*administration & dosage ; Delay Discounting/*drug effects ; Pain Measurement/*drug effects; Adult ; Analgesics, Opioid/economics ; Delay Discounting/physiology ; Drug Prescriptions/economics ; Female ; Humans ; Male ; Marijuana Smoking/economics ; Marijuana Smoking/psychology ; Opioid-Related Disorders/economics ; Opioid-Related Disorders/prevention & control ; Opioid-Related Disorders/psychology ; Pain Measurement/economics ; Pain Measurement/psychology ; Reproducibility of Results ; Risk Factors ; Self Report ; Substance-Related Disorders/economics ; Substance-Related Disorders/prevention & control ; Substance-Related Disorders/psychology ; Young Adult
    • Abstract:
      Rationale: Non-medical prescription opioid use and opioid use disorder (OUD) present a significant public health concern. Identifying behavioral mechanisms underlying OUD will assist in developing improved prevention and intervention approaches. Behavioral economic demand has been extensively evaluated as a measure of reinforcer valuation for alcohol and cigarettes, whereas prescription opioids have received comparatively little attention.
      Objectives: Utilize a purchase task procedure to measure the incremental validity and test-retest reliability of opioid demand.
      Methods: Individuals reporting past year non-medical prescription opioid use were recruited using the crowdsourcing platform Amazon Mechanical Turk (mTurk). Participants completed an opioid purchase task as well as measures of cannabis demand, delay discounting, and self-reported pain. A 1-month follow-up was used to evaluate test-retest reliability.
      Results: More intense and inelastic opioid demand was associated with OUD and more intense cannabis demand was associated with cannabis use disorder. Multivariable models indicated that higher opioid intensity and steeper opioid delay discounting rates each significantly and uniquely predicted OUD. Increased opioid demand intensity, but not elasticity, was associated with higher self-reported pain, and no relationship was observed with perceived pain relief from opioids. Opioid demand showed acceptable-to-good test-retest reliability (e.g., intensity r xx  = .75; elasticity r xx  = .63). Temporal reliability was lower for cannabis demand (e.g., intensity r xx  = .53; elasticity r xx  = .58) and discounting rates (r xx  = .42-.61).
      Conclusions: Opioid demand was incrementally valid and test-retest reliable as measured by purchase tasks. These findings support behavioral economic demand as a clinically useful measure of drug valuation that is sensitive to individual difference variables.
    • References:
      JAMA. 2015 Jun 23-30;313(24):2474-83. (PMID: 26103031)
      Curr HIV/AIDS Rep. 2018 Jun;15(3):245-254. (PMID: 29796965)
      Exp Clin Psychopharmacol. 1999 Nov;7(4):412-26. (PMID: 10609976)
      J Behav Med. 2017 Oct;40(5):832-838. (PMID: 28508382)
      Exp Clin Psychopharmacol. 2015 Oct;23(5):377-86. (PMID: 26147181)
      Addiction. 2012 Mar;107(3):587-96. (PMID: 21883604)
      Drug Alcohol Depend. 2012 Jun 1;123(1-3):15-21. (PMID: 22055012)
      Drug Alcohol Depend. 2016 Mar 1;160:127-34. (PMID: 26785634)
      Drug Alcohol Depend. 2015 Feb 1;147:190-5. (PMID: 25533895)
      Exp Clin Psychopharmacol. 2017 Jun;25(3):198-207. (PMID: 28493743)
      Nicotine Tob Res. 2012 Jun;14(6):761-5. (PMID: 22157231)
      Lancet. 1999 May 29;353(9167):1865-9. (PMID: 10359427)
      Psychopharmacology (Berl). 2017 Aug;234(16):2421-2429. (PMID: 28508921)
      Psychol Rev. 2008 Jan;115(1):186-98. (PMID: 18211190)
      Drug Alcohol Depend. 2015 Nov 1;156:304-310. (PMID: 26460141)
      Alcohol Clin Exp Res. 2016 Apr;40(4):672-85. (PMID: 26993151)
      Exp Clin Psychopharmacol. 2009 Dec;17(6):396-404. (PMID: 19968404)
      Tob Regul Sci. 2017 Apr;3(2):139-150. (PMID: 28824938)
      JAMA. 2016 Nov 1;316(17):1763-1764. (PMID: 27802551)
      J Exp Psychol Gen. 1999 Mar;128(1):78-87. (PMID: 10100392)
      J Exp Anal Behav. 2013 Jan;99(1):98-124. (PMID: 23344991)
      J Consult Clin Psychol. 2015 Dec;83(6):1033-43. (PMID: 26167945)
      Exp Clin Psychopharmacol. 2012 Jun;20(3):181-90. (PMID: 22429255)
      N Engl J Med. 2015 Jul 30;373(5):397-9. (PMID: 26106947)
      Exp Clin Psychopharmacol. 2019 Feb;27(1):1-18. (PMID: 30489114)
      Soc Psychol Personal Sci. 2017 May;8(4):355-362. (PMID: 28736600)
      Behav Processes. 2017 Aug;141(Pt 1):33-41. (PMID: 28373056)
      J Stud Alcohol Drugs. 2013 Jul;74(4):626-34. (PMID: 23739028)
      Psychopharmacology (Berl). 2013 Mar;226(2):371-80. (PMID: 23229641)
      Behav Processes. 2016 Oct;131:15-23. (PMID: 27498073)
      Behav Processes. 2010 Jan;83(1):23-30. (PMID: 19744547)
      Psychol Addict Behav. 2017 Nov;31(7):797-806. (PMID: 29144150)
      Annu Rev Public Health. 2015 Mar 18;36:559-74. (PMID: 25581144)
      Addict Behav. 2012 Nov;37(11):1257-63. (PMID: 22727784)
      PLoS One. 2016 Jun 28;11(6):e0157732. (PMID: 27351378)
      Pain. 1988 Apr;33(1):11-23. (PMID: 2454440)
      N Engl J Med. 2016 Jan 14;374(2):154-63. (PMID: 26760086)
      Pain Physician. 2012 Jul;15(3 Suppl):ES67-92. (PMID: 22786463)
      Drug Alcohol Depend. 2018 Oct 1;191:117-140. (PMID: 30099174)
      J Psychoactive Drugs. 2012 Apr-Jun;44(2):125-33. (PMID: 22880540)
      BMC Med Res Methodol. 2017 Dec 1;17(1):156. (PMID: 29191161)
      J Exp Anal Behav. 2018 Jul;110(1):136-153. (PMID: 29873806)
      Exp Clin Psychopharmacol. 2014 Jun;22(3):222-8. (PMID: 24708144)
      J Rural Health. 2018 Dec;34(1):6-13. (PMID: 28685864)
      Psychol Addict Behav. 2017 Feb;31(1):85-94. (PMID: 27893213)
      Eur J Pain. 2006 May;10(4):353-61. (PMID: 16051509)
      Am J Transplant. 2017 Dec;17(12):3241-3252. (PMID: 29145698)
      Drug Alcohol Depend. 2015 Jul 1;152:32-8. (PMID: 26002377)
      Addiction. 2004 Apr;99(4):461-71. (PMID: 15049746)
      Psychopharmacology (Berl). 2009 Mar;203(1):33-40. (PMID: 18925387)
      J Stud Alcohol Drugs. 2018 Nov;79(6):929-934. (PMID: 30573024)
      Annu Rev Clin Psychol. 2016;12:53-81. (PMID: 26772208)
      J Exp Anal Behav. 2006 Jan;85(1):73-93. (PMID: 16602377)
      J Abnorm Psychol. 2003 Aug;112(3):382-92. (PMID: 12943017)
      MMWR Morb Mortal Wkly Rep. 2015 May 1;64(16):443-4. (PMID: 25928470)
      Behav Processes. 2008 Mar;77(3):334-42. (PMID: 17919848)
      Behav Processes. 2017 Jul;140:33-40. (PMID: 28347716)
      Exp Clin Psychopharmacol. 2007 Apr;15(2):187-94. (PMID: 17469942)
      J Acquir Immune Defic Syndr. 2016 Nov 1;73(3):323-331. (PMID: 27763996)
      Psychopharmacology (Berl). 2011 Sep;217(2):177-87. (PMID: 21487658)
      Exp Clin Psychopharmacol. 2016 Feb;24(1):38-47. (PMID: 26502300)
      Clin Pharmacol Ther. 2017 Feb;101(2):185-187. (PMID: 27509043)
      Appetite. 2018 Jan 1;120:67-74. (PMID: 28847564)
      N Engl J Med. 2017 Jul 27;377(4):391-394. (PMID: 28564549)
      Exp Clin Psychopharmacol. 2015 Dec;23(6):504-12. (PMID: 26280591)
      Drug Alcohol Depend. 2007 Jul 10;89(2-3):227-33. (PMID: 17289297)
      Natl Vital Stat Rep. 2016 Dec;65(10):1-15. (PMID: 27996932)
    • Grant Information:
      R01 DA047368 United States DA NIDA NIH HHS; Graduate Research Grant Psi Chi; 1247392 National Science Foundation; Professional Development Funds University of Kentucky Department of Behavioral Science
    • Contributed Indexing:
      Keywords: Behavioral economics; Cannabis; Demand; Discounting; Opioid; Pain; Purchase task; Reliability; mTurk
    • Accession Number:
      0 (Analgesics, Opioid)
    • Publication Date:
      Date Created: 20190331 Date Completed: 20191126 Latest Revision: 20240328
    • Publication Date:
      20240329
    • Accession Number:
      PMC6990908
    • Accession Number:
      10.1007/s00213-019-05234-y
    • Accession Number:
      30927021