Strategies for optimising musculoskeletal health in the 21 ^st century.

Publisher: BioMed Central Country of Publication: England NLM ID: 100968565 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2474 (Electronic) Linking ISSN: 14712474 NLM ISO Abbreviation: BMC Musculoskelet Disord

Original Publication: London : BioMed Central, [2000-

Cost of Illness* ; Global Health* ; Musculoskeletal Physiological Phenomena*; Aging/*physiology ; Musculoskeletal Diseases/*prevention & control; Consensus Development Conferences as Topic ; Health Status ; Healthy Aging/physiology ; Humans ; Interdisciplinary Communication ; International Cooperation ; Musculoskeletal Diseases/diagnosis ; Musculoskeletal Diseases/economics ; Musculoskeletal Diseases/epidemiology ; Risk Factors

We live in a world with an ever-increasing ageing population. Studying healthy ageing and reducing the socioeconomic impact of age-related diseases is a key research priority for the industrialised and developing countries, along with a better mechanistic understanding of the physiology and pathophysiology of ageing that occurs in a number of age-related musculoskeletal disorders. Arthritis and musculoskeletal disorders constitute a major cause of disability and morbidity globally and result in enormous costs for our health and social-care systems.By gaining a better understanding of healthy musculoskeletal ageing and the risk factors associated with premature ageing and senescence, we can provide better care and develop new and better-targeted therapies for common musculoskeletal disorders. This review is the outcome of a two-day multidisciplinary, international workshop sponsored by the Institute of Advanced Studies entitled "Musculoskeletal Health in the 21st Century" and held at the University of Surrey from 30th June-1st July 2015.The aim of this narrative review is to summarise current knowledge of musculoskeletal health, ageing and disease and highlight strategies for prevention and reducing the impact of common musculoskeletal diseases.

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305815 FP7 Health; 115770 European Commission; DOTSUT-215 European Commission; 20194 United Kingdom Arthritis Research UK; 1-141/1434 HiCi King Abdulaziz University; DOTSUT-215 European Social Fund

Keywords: Ageing; Global burden; Joint diseases; Low back pain (LBP); Metabolic disease; Musculoskeletal disorders; Musculoskeletal health; Obesity; Osteoarthritis (OA); Osteoporosis (OP); Rheumatoid arthritis (RA); Sarcopenia; Type II diabetes

Date Created: 20190412 Date Completed: 20190812 Latest Revision: 20200225

20240104

PMC6458786

10.1186/s12891-019-2510-7

30971232