Gender-affirming care, mental health, and economic stability in the time of COVID-19: A multi-national, cross-sectional study of transgender and nonbinary people.

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  • Additional Information
    • Source:
      Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
    • Publication Information:
      Original Publication: San Francisco, CA : Public Library of Science
    • Subject Terms:
    • Abstract:
      Background: Transgender and nonbinary people are disproportionately affected by structural barriers to quality healthcare, mental health challenges, and economic hardship. This study examined the impact of the novel coronavirus disease (COVID-19) crisis and subsequent control measures on gender-affirming care, mental health, and economic stability among transgender and nonbinary people in multiple countries.
      Methods: We collected multi-national, cross-sectional data from 964 transgender and nonbinary adult users of the Hornet and Her apps from April to August 2020 to characterize changes in gender-affirming care, mental health, and economic stability as a result of COVID-19. We conducted Poisson regression models to assess if access to gender-affirming care and ability to live according to one's gender were related to depressive symptoms, anxiety, and changes in suicidal ideation.
      Results: Individuals resided in 76 countries, including Turkey (27.4%, n = 264) and Thailand (20.6%, n = 205). A majority were nonbinary (66.8%, n = 644) or transfeminine (29.4%, n = 283). Due to COVID-19, 55.0% (n = 320/582) reported reduced access to gender-affirming resources, and 38.0% (n = 327/860) reported reduced time lived according to their gender. About half screened positive for depression (50.4%,442/877) and anxiety (45.8%, n = 392/856). One in six (17.0%, n = 112/659) expected losses of health insurance, and 77.0% (n = 724/940) expected income reductions. The prevalence of depressive symptoms, anxiety, and increased suicidal ideation were 1.63 (95% CI: 1.36-1.97), 1.61 (95% CI: 1.31-1.97), and 1.74 (95% CI: 1.07-2.82) times higher for individuals whose access to gender-affirming resources was reduced versus not.
      Discussion: The COVID-19 crisis is associated with reduced access to gender-affirming resources and the ability of transgender and nonbinary people to live according to their gender worldwide. These reductions may drive the increased depressive symptoms, anxiety, and suicidal ideation reported in this sample. To improve health of transgender and nonbinary communities, increased access to gender-affirming resources should be prioritized through policies (e.g., digital prescriptions), flexible interventions (e.g., telehealth), and support for existing transgender health initiatives.
      Competing Interests: SWB has received funding from Viiv Healthcare as a consultant. SH is the co-founder, chairman, and president of Hornet. Participant recruitment was conducted via the Hornet app. No other authors had competing interests to declare. This does not alter our adherence to PLOS ONE policies on sharing data and materials.
    • Comments:
      Update of: medRxiv. 2020 Nov 04;:. (PMID: 33173876)
    • References:
      Ann Epidemiol. 2020 Jul;47:37-44. (PMID: 32419766)
      JAMA. 2020 Jun 23;323(24):2478-2480. (PMID: 32391852)
      Global Health. 2020 Jul 6;16(1):57. (PMID: 32631403)
      Int J Surg. 2020 Jun;78:185-193. (PMID: 32305533)
      Psychosomatics. 2009 Nov-Dec;50(6):613-21. (PMID: 19996233)
      Clin Psychol Rev. 2018 Dec;66:24-38. (PMID: 29627104)
      Lancet. 2016 Jul 23;388(10042):412-436. (PMID: 27323919)
      MMWR Morb Mortal Wkly Rep. 2020 Aug 14;69(32):1049-1057. (PMID: 32790653)
      J Adolesc Health. 2020 Nov;67(5):645-648. (PMID: 32933837)
      Nat Hum Behav. 2021 May;5(5):557-565. (PMID: 33785897)
      J Acquir Immune Defic Syndr. 2021 May 1;87(1):644-651. (PMID: 33443963)
      Perspect Biol Med. 2007 Autumn;50(4):481-90. (PMID: 17951883)
      Am J Psychiatry. 2020 Aug 1;177(8):727-734. (PMID: 31581798)
      JAMA Netw Open. 2020 Sep 1;3(9):e2019686. (PMID: 32876685)
      Transgend Health. 2018 Dec 14;3(1):170-178. (PMID: 30564633)
      Qual Health Res. 2017 Dec;27(14):2138-2149. (PMID: 28836483)
      PLoS One. 2020 Feb 21;15(2):e0228765. (PMID: 32084144)
      J Adolesc Health. 2020 Sep;67(3):450-452. (PMID: 32591304)
      Nutrients. 2020 Jul 15;12(7):. (PMID: 32679788)
      Nat Hum Behav. 2021 Apr;5(4):529-538. (PMID: 33686204)
      Soc Sci Med. 2015 Dec;147:222-31. (PMID: 26599625)
      Clin Chem. 2019 Jan;65(1):119-134. (PMID: 30602477)
      J Acquir Immune Defic Syndr. 2020 Dec 15;85(5):e90-e92. (PMID: 32947443)
      MMWR Morb Mortal Wkly Rep. 2020 Aug 21;69(33):1133-1138. (PMID: 32817604)
      BMJ Glob Health. 2020 Aug;5(8):. (PMID: 32819917)
      Lancet Psychiatry. 2020 Sep;7(9):813-824. (PMID: 32682460)
      N Engl J Med. 2020 Oct 8;383(15):1483-1488. (PMID: 32706956)
      Lancet Diabetes Endocrinol. 2020 Jul;8(7):564-565. (PMID: 32445629)
      Transgend Health. 2021 Oct 04;6(5):235-239. (PMID: 34993295)
      AIDS Behav. 2020 Sep;24(9):2477-2479. (PMID: 32338329)
      Arch Sex Behav. 2013 Apr;42(3):327-30. (PMID: 23440563)
      Curr Psychiatry Rep. 2018 Oct 11;20(12):110. (PMID: 30306351)
      AIDS Behav. 2021 Feb;25(2):311-321. (PMID: 32654021)
      Lancet Infect Dis. 2020 May;20(5):533-534. (PMID: 32087114)
      Urol Clin North Am. 2019 Nov;46(4):475-486. (PMID: 31582022)
      Wellcome Open Res. 2020 May 6;5:88. (PMID: 32613083)
      AIDS Behav. 2020 Jul;24(7):2009-2012. (PMID: 32415617)
      Arch Sex Behav. 2020 Feb;49(2):645-659. (PMID: 31485801)
      Health Serv Res. 2019 Dec;54 Suppl 2:1454-1466. (PMID: 31659745)
      J Acquir Immune Defic Syndr. 2020 Dec 1;85(4):e67-e69. (PMID: 33136755)
      Sex Roles. 2013 Jun 1;68(11-12):675-689. (PMID: 23729971)
      J Homosex. 2021 Mar 21;68(4):592-611. (PMID: 33502286)
      Cult Health Sex. 2017 Jan;19(1):64-75. (PMID: 27300085)
      Clin Endocrinol (Oxf). 2010 Feb;72(2):214-31. (PMID: 19473181)
      Arch Sex Behav. 2020 Jul;49(5):1395-1399. (PMID: 32519279)
      Health Soc Work. 2019 Aug 2;44(3):149-155. (PMID: 31359065)
      Lancet Glob Health. 2020 Jun;8(6):e737. (PMID: 32446335)
      Neuropsychiatr Dis Treat. 2016 Aug 04;12:1953-66. (PMID: 27536118)
      Int J Transgend. 2019 Jul 25;20(2-3):119-125. (PMID: 32999599)
      J Homosex. 2020 Oct 14;67(12):1675-1690. (PMID: 31125297)
      Int J Transgend Health. 2021 Oct 18;24(3):346-359. (PMID: 37519919)
      J Sex Res. 2016;53(1):85-97. (PMID: 25621903)
    • Grant Information:
      F31 MH121128 United States MH NIMH NIH HHS; K01 MH114715 United States MH NIMH NIH HHS; R01 MH110358 United States MH NIMH NIH HHS; T32 AI102623 United States AI NIAID NIH HHS
    • Publication Date:
      Date Created: 20210709 Date Completed: 20210719 Latest Revision: 20240402
    • Publication Date:
      20240402
    • Accession Number:
      PMC8270151
    • Accession Number:
      10.1371/journal.pone.0254215
    • Accession Number:
      34242317