The effect of fear of progression on quality of life among breast cancer patients: the mediating role of social support.

Publisher: BioMed Central Country of Publication: England NLM ID: 101153626 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-7525 (Electronic) Linking ISSN: 14777525 NLM ISO Abbreviation: Health Qual Life Outcomes Subsets: MEDLINE

Original Publication: [London] : BioMed Central, c2003-

Social Support*; Breast Neoplasms/*psychology ; Fear/*psychology ; Quality of Life/*psychology ; Stress, Psychological/*psychology; Adult ; Breast Neoplasms/therapy ; China ; Cross-Sectional Studies ; Female ; Humans ; Middle Aged ; Regression Analysis ; Surveys and Questionnaires

Background: Women with breast cancer are prone to have mental stress and be stimulated by the fear of progression (FOP), then giving rise to a lower quality of life (QOL). The study aimed to examine the relationships between FOP, social support and QOL, and further explore whether social support mediates the association between FOP and QOL among Chinese patients with breast cancer.
Methods: The cross-sectional study was conducted from October 2019 to May 2020 at Anshan Cancer Hospital in Liaoning, China. 244 female breast cancer patients completed questionnaires including the Functional Assessment of Cancer Therapy for Breast (FACT-B), Multi-Dimensional Scale of Perceived Social Support (MSPSS), and Fear of Progression (FOP). Hierarchical multiple regression analysis was performed to assess the associations between FOP, social support and QOL. Asymptotic and resampling strategies were used to explore the mediating role of social support.
Results: The mean QOL score was 90.6 ± 17.0 among the patients with breast cancer. FOP was negatively correlated with QOL, while social support was positively related to QOL. Social support partly mediated the association between FOP and QOL, and the proportion of the mediating effect accounted for by social support was 25%.
Conclusions: Chinese breast cancer patients expressed low QOL. Social support could mediate the association between FOP and QOL. Medical staffs and cancer caregivers should alleviate patients' FOP to improve their QOL by facilitating social support.
(© 2021. The Author(s).)

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71904204 National Natural Science Foundation of China

Keywords: Breast cancer; Fear of progression; Quality of life; Social support

Date Created: 20210713 Date Completed: 20210720 Latest Revision: 20210720

20240105

PMC8276515

10.1186/s12955-021-01816-7

34253195