Trends in COVID-19 Cases, Emergency Department Visits, and Hospital Admissions Among Children and Adolescents Aged 0-17 Years - United States, August 2020-August 2021.

Publisher: U.S. Centers for Disease Control Country of Publication: United States NLM ID: 7802429 Publication Model: Electronic Cited Medium: Internet ISSN: 1545-861X (Electronic) Linking ISSN: 01492195 NLM ISO Abbreviation: MMWR Morb Mortal Wkly Rep Subsets: MEDLINE

Publication: Atlanta, GA : U.S. Centers for Disease Control
Original Publication: [Atlanta] U. S. Dept. of Health, Education, and Welfare, Public Health Service, Center for Disease Control.

COVID-19/*epidemiology ; COVID-19/*therapy ; Emergency Service, Hospital/*statistics & numerical data ; Facilities and Services Utilization/*trends ; Hospitalization/*trends; Adolescent ; COVID-19/prevention & control ; COVID-19 Vaccines/administration & dosage ; Child ; Child, Preschool ; Humans ; Infant ; Infant, Newborn ; Severity of Illness Index ; United States/epidemiology ; Vaccination Coverage/statistics & numerical data

Although COVID-19 generally results in milder disease in children and adolescents than in adults, severe illness from COVID-19 can occur in children and adolescents and might require hospitalization and intensive care unit (ICU) support (1-3). It is not known whether the B.1.617.2 (Delta) variant,* which has been the predominant variant of SARS-CoV-2 (the virus that causes COVID-19) in the United States since late June 2021, ^† causes different clinical outcomes in children and adolescents compared with variants that circulated earlier. To assess trends among children and adolescents, CDC analyzed new COVID-19 cases, emergency department (ED) visits with a COVID-19 diagnosis code, and hospital admissions of patients with confirmed COVID-19 among persons aged 0-17 years during August 1, 2020-August 27, 2021. Since July 2021, after Delta had become the predominant circulating variant, the rate of new COVID-19 cases and COVID-19-related ED visits increased for persons aged 0-4, 5-11, and 12-17 years, and hospital admissions of patients with confirmed COVID-19 increased for persons aged 0-17 years. Among persons aged 0-17 years during the most recent 2-week period (August 14-27, 2021), COVID-19-related ED visits and hospital admissions in the states with the lowest vaccination coverage were 3.4 and 3.7 times that in the states with the highest vaccination coverage, respectively. At selected hospitals, the proportion of COVID-19 patients aged 0-17 years who were admitted to an ICU ranged from 10% to 25% during August 2020-June 2021 and was 20% and 18% during July and August 2021, respectively. Broad, community-wide vaccination of all eligible persons is a critical component of mitigation strategies to protect pediatric populations from SARS-CoV-2 infection and severe COVID-19 illness.
Competing Interests: All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. Sapna Bamrah Morris serves on the data safety monitoring board for the PaTS COVID Cohort2 Trial (Africa). No other potential conflicts of interest were disclosed.

Erratum in: MMWR Morb Mortal Wkly Rep. 2021 Sep 24;70(38):1355. (PMID: 34661565)

Lancet. 2021 Jun 26;397(10293):2461-2462. (PMID: 34139198)
Pediatr Infect Dis J. 2021 Aug 5;:. (PMID: 34371507)
Acta Paediatr. 2020 Jun;109(6):1088-1095. (PMID: 32202343)
Pediatrics. 2020 Oct;146(4):. (PMID: 32680880)
MMWR Morb Mortal Wkly Rep. 2021 Sep 10;70(36):1255-1260. (PMID: 34499627)
MMWR Morb Mortal Wkly Rep. 2020 Jul 17;69(28):933-937. (PMID: 32673303)
JAMA Netw Open. 2021 Jun 1;4(6):e2111182. (PMID: 34097050)
N Engl J Med. 2021 Aug 12;385(7):585-594. (PMID: 34289274)
J Pediatr. 2021 Mar;230:23-31.e10. (PMID: 33197493)

0 (COVID-19 Vaccines)

Date Created: 20210909 Date Completed: 20210910 Latest Revision: 20220408

20240105

PMC8437056

10.15585/mmwr.mm7036e1

34499628