Beneficial Effects of Plant Extracts and Bioactive Food Components in Childhood Supplementation.

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  • Additional Information
    • Source:
      Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE
    • Publication Information:
      Original Publication: Basel, Switzerland : MDPI Publishing
    • Subject Terms:
    • Abstract:
      The pivotal role of childhood nutrition has always roused a growing interest from the scientific community. Plant extracts and bioactive dietary components play a significant role in the maintenance of human health and wellness, with the potential to modulate risk factors and manage symptoms for a large number of common childhood disorders such as memory impairment, respiratory illnesses, gastrointestinal disorders, metabolic derangements, and pathologies related to the oral cavity. This review is designed to highlight the health benefits of botanical extracts and bioactive dietary components in children as evidenced by clinical trials, considering their safety with regards to childhood sensibilities. The supplementation of children with the herbal extracts or bioactive components mentioned in this review leads to the conclusion that they are useful for treating various ailments, with no serious adverse events being reported. However, for the limited number of investigations specifically focused on the safety of such products in children, time is needed to expand the literature data covering the safety of childhood supplementation with botanical extract and bioactive food components.
    • References:
      Clin Nutr ESPEN. 2018 Aug;26:47-52. (PMID: 29908682)
      J Am Coll Nutr. 2006 Oct;25(5):415-9. (PMID: 17031011)
      BMC Complement Altern Med. 2018 Jan 09;18(1):7. (PMID: 29316908)
      Food Chem. 2018 Jun 1;250:67-74. (PMID: 29412929)
      Food Chem. 2018 Jul 1;253:13-21. (PMID: 29502812)
      Biotech Histochem. 2017;92(4):274-282. (PMID: 28426256)
      Eur J Med Res. 1998 Nov 17;3(11):511-4. (PMID: 9810030)
      Pediatr Res. 2013 Dec;74(6):737-41. (PMID: 24002333)
      Am Fam Physician. 2005 Mar 15;71(6):1068, 1071. (PMID: 15791888)
      Front Pediatr. 2019 Nov 14;7:431. (PMID: 31803694)
      Klin Padiatr. 2000 Jul-Aug;212(4):189-95. (PMID: 10994549)
      Trop Med Int Health. 2010 Oct;15(10):1148-55. (PMID: 20723187)
      Prz Gastroenterol. 2013;8(6):350-3. (PMID: 24868283)
      Pediatr Emerg Care. 2001 Jun;17(3):165-9. (PMID: 11437139)
      Swiss Med Wkly. 2012 Jun 06;142:w13596. (PMID: 22674349)
      Phytomedicine. 2016 Dec 15;23(14):1735-1742. (PMID: 27912875)
      JAMA. 2004 Dec 15;292(23):2868-73. (PMID: 15598918)
      Phytother Res. 2006 Jul;20(7):519-30. (PMID: 16628544)
      Med J Aust. 2008 Mar 17;188(6):355-9. (PMID: 18341460)
      New Phytol. 2018 Aug;219(3):1124-1133. (PMID: 29856474)
      Nutr Neurosci. 2018 Nov;21(9):676-681. (PMID: 28686541)
      Plant Cell Rep. 2009 Jan;28(1):123-33. (PMID: 18854999)
      Cancer Chemother Pharmacol. 2003 May;51(5):439-44. (PMID: 12736763)
      Evid Based Complement Alternat Med. 2018 May 16;2018:7860456. (PMID: 29887909)
      Complement Ther Med. 2017 Feb;30:14-23. (PMID: 28137522)
      Pediatrics. 2008 Aug;122(2):398-417. (PMID: 18676559)
      Planta Med. 1991 Jun;57(3):212-6. (PMID: 1680240)
      J Pediatr. 1999 Dec;135(6):689-97. (PMID: 10586170)
      Neurogastroenterol Motil. 2017 Dec;29(12):. (PMID: 28665038)
      JAMA Pediatr. 2018 Jul 1;172(7):646-654. (PMID: 29813149)
      BMC Complement Altern Med. 2016 Nov 9;16(1):450. (PMID: 27829428)
      Explore (NY). 2007 Jul-Aug;3(4):378-85. (PMID: 17681258)
      J Pediatr Gastroenterol Nutr. 2016 Apr;62(4):618-26. (PMID: 26465792)
      Wien Med Wochenschr. 2013 Feb;163(3-4):52-7. (PMID: 23179673)
      BMC Pediatr. 2021 Jan 11;21(1):29. (PMID: 33430841)
      J Diet Suppl. 2010 Jun;7(2):179-215. (PMID: 22435615)
      Am J Hematol. 2007 May;82(5):357-62. (PMID: 17373676)
      Eur J Clin Nutr. 2012 Sep;66(9):1020-3. (PMID: 22692023)
      Therapie. 1998 Jan-Feb;53(1):82-3. (PMID: 9773106)
      Eur Rev Med Pharmacol Sci. 2016 Mar;20(5):923-9. (PMID: 27010152)
      PLoS One. 2015 May 08;10(5):e0125375. (PMID: 25955295)
      Front Pharmacol. 2017 Jul 17;8:430. (PMID: 28769789)
      Nutrients. 2020 Feb 01;12(2):. (PMID: 32024101)
      J Pediatr Gastroenterol Nutr. 2004 Apr;38(4):365-74. (PMID: 15085012)
      Int J Food Microbiol. 2008 Feb 10;121(3):357-60. (PMID: 18068252)
      Children (Basel). 2014 Aug 25;1(2):149-65. (PMID: 27417473)
      JAMA. 2016 Jan 26;315(4):362-70. (PMID: 26813209)
      Nutr Rev. 2009 Nov;67(11):615-23. (PMID: 19906248)
      Epilepsia. 1998 Nov;39(11):1216-25. (PMID: 9821988)
      Am J Respir Crit Care Med. 2011 Dec 15;184(12):1342-9. (PMID: 21908411)
      J Pediatr. 2012 Nov;161(5):837-42. (PMID: 22717218)
      J Atten Disord. 2010 Nov;14(3):281-91. (PMID: 20228219)
      Wien Med Wochenschr. 2013 Feb;163(3-4):46-51. (PMID: 23377951)
      J Biol Chem. 2018 Jul 20;293(29):11600-11611. (PMID: 29880645)
      BMC Res Notes. 2015 Feb 03;8:23. (PMID: 25643669)
      Clin Infect Dis. 2008 Feb 1;46 Suppl 2:S104-11; discussion S144-51. (PMID: 18181712)
      Plant Cell Rep. 2009 Jul;28(7):1137-43. (PMID: 19430793)
      BMC Infect Dis. 2010 Aug 25;10:253. (PMID: 20735858)
      J Altern Complement Med. 2019 Jun;25(6):567-577. (PMID: 30912673)
      Crit Rev Food Sci Nutr. 2019;59(8):1334-1346. (PMID: 29236516)
      Clin Nutr. 2016 Feb;35(1):34-40. (PMID: 25701159)
      BMJ. 2008 Feb 2;336(7638):266-8. (PMID: 18184631)
      J Pediatr Pharmacol Ther. 2013 Oct;18(4):277-91. (PMID: 24719588)
      BMC Complement Altern Med. 2018 Jul 3;18(1):201. (PMID: 29970065)
      Ital J Pediatr. 2014 Jun 10;40:56. (PMID: 24917119)
      J Pharm Biomed Anal. 2014 Jun;94:163-72. (PMID: 24603350)
      Am J Clin Nutr. 2002 Sep;76(3):646-52. (PMID: 12198013)
      Curr Opin Clin Nutr Metab Care. 2012 Sep;15(5):474-9. (PMID: 22797568)
      Phytother Res. 2019 May;33(5):1457-1468. (PMID: 30838706)
      Int J Mol Sci. 2020 Jul 13;21(14):. (PMID: 32668581)
      Gastroenterology. 2004 Aug;127(2):630-4. (PMID: 15300594)
      Eur J Pediatr. 2010 Jan;169(1):55-62. (PMID: 19343362)
      World J Pediatr. 2017 Feb;13(1):27-33. (PMID: 27457790)
      Biol Trace Elem Res. 2019 Apr;188(2):508-513. (PMID: 29911262)
      Pediatrics. 2011 Jun;127(6):1060-6. (PMID: 21536609)
      Prz Gastroenterol. 2013;8(5):295-8. (PMID: 24868272)
      J Nutr. 2003 Nov;133(11 Suppl 2):4010S-4020S. (PMID: 14672304)
      Appl Physiol Nutr Metab. 2018 Jan;43(1):77-83. (PMID: 28892646)
      Phytomedicine. 2019 May;58:152869. (PMID: 30831467)
      J Clin Microbiol. 2014 Feb;52(2):398-406. (PMID: 24478468)
      Complement Ther Med. 2019 Dec;47:102214. (PMID: 31780029)
      Foods. 2017 Aug 28;6(9):. (PMID: 28846628)
      Biomed Pharmacother. 2018 Oct;106:1767-1774. (PMID: 30119252)
      Lancet. 2007 Oct 6;370(9594):1230-9. (PMID: 17920918)
      Phytomedicine. 2006 Jun;13(6):383-7. (PMID: 16487692)
      Nutrients. 2016 May 11;8(5):. (PMID: 27187450)
      Nutrients. 2018 Oct 16;10(10):. (PMID: 30332744)
      BMC Complement Altern Med. 2016 Feb 24;16:77. (PMID: 26912265)
      Pediatrics. 2013 Sep;132(3):e666-76. (PMID: 23958764)
      Am J Clin Nutr. 2013 Jun;97(6):1331-7. (PMID: 23576049)
      Nutrients. 2017 Jul 28;9(8):. (PMID: 28788094)
      PLoS One. 2015 Oct 19;10(10):e0140331. (PMID: 26479870)
      Pediatrics. 2012 Sep;130(3):e561-7. (PMID: 22908115)
      Molecules. 2018 Apr 21;23(4):. (PMID: 29690516)
      EBioMedicine. 2016 Apr;6:246-252. (PMID: 27211567)
      Altern Ther Health Med. 2003 Jul-Aug;9(4):58-61. (PMID: 12868253)
      Nutr Hosp. 2017 Oct 15;34(Suppl 4):58-61. (PMID: 29156934)
      Crit Rev Food Sci Nutr. 2018 Mar 24;58(5):785-807. (PMID: 27645583)
      J Clin Pharm Ther. 2001 Oct;26(5):363-7. (PMID: 11679026)
      Curr Med Res Opin. 2004 Jan;20(1):63-71. (PMID: 14741074)
      Bone Marrow Transplant. 2016 Feb;51(2):262-6. (PMID: 26569091)
      Inflamm Bowel Dis. 2011 Feb;17(2):573-82. (PMID: 20848527)
      BMC Infect Dis. 2012 May 10;12:111. (PMID: 22574737)
      Am J Clin Nutr. 2015 Nov;102(5):1113-25. (PMID: 26447156)
      Phytother Res. 2006 Feb;20(2):96-102. (PMID: 16444660)
      Front Immunol. 2019 Jan 15;9:3160. (PMID: 30697214)
      Avicenna J Phytomed. 2019 Mar-Apr;9(2):126-133. (PMID: 30984577)
      Pediatrics. 2003 Jul;112(1 Pt 2):240-6. (PMID: 12837916)
      Am J Clin Nutr. 2004 Sep;80(3):729-36. (PMID: 15321815)
      J Pediatr Endocrinol Metab. 2003 Oct-Nov;16(8):1105-9. (PMID: 14594170)
    • Contributed Indexing:
      Keywords: bioactive components; childhood disorders; childhood supplementation; plant extracts
    • Accession Number:
      0 (Phytochemicals)
      0 (Plant Extracts)
    • Publication Date:
      Date Created: 20210928 Date Completed: 20211022 Latest Revision: 20211022
    • Publication Date:
      20240105
    • Accession Number:
      PMC8464764
    • Accession Number:
      10.3390/nu13093157
    • Accession Number:
      34579034