Peering into the future: Eye movements predict neural repetition effects during episodic simulation.

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  • Additional Information
    • Source:
      Publisher: Pergamon Press Country of Publication: England NLM ID: 0020713 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3514 (Electronic) Linking ISSN: 00283932 NLM ISO Abbreviation: Neuropsychologia Subsets: MEDLINE
    • Publication Information:
      Publication: Oxford : Pergamon Press
      Original Publication: Oxford.
    • Subject Terms:
    • Abstract:
      Imagining future scenarios involves recombining different elements of past experiences into a coherent event, a process broadly supported by the brain's default network. Prior work suggests that distinct brain regions may contribute to the inclusion of different simulation features. Here we examine how activity in these brain regions relates to the vividness of future simulations. Thirty-four healthy young adults imagined future events with familiar people and locations in a two-part study involving a repetition suppression paradigm. First, participants imagined events while their eyes were tracked during a behavioral session. Immediately after, participants imagined events during MRI scanning. The events to be imagined were manipulated such that some were identical to those imagined in the behavioral session while others involved new locations, new people, or both. In this way, we could examine how self-report ratings and eye movements predict brain activity during simulation along with specific simulation features. Vividness ratings were negatively correlated with eye movements, in contrast to an often-observed positive relationship with past recollection. Moreover, fewer eye movements predicted greater involvement of the hippocampus during simulation, an effect specific to location features. Our findings suggest that eye movements may facilitate scene construction for future thinking, lending support to frameworks that spatial information forms the foundation of episodic simulation.
      (Copyright © 2024 Elsevier Ltd. All rights reserved.)
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    • Grant Information:
      R01 AG008441 United States AG NIA NIH HHS; Z01 AG000841 United States ImNIH Intramural NIH HHS
    • Contributed Indexing:
      Keywords: Default network; Episodic simulation; Eye movements; Hippocampus; Vividness
    • Publication Date:
      Date Created: 20240320 Date Completed: 20240329 Latest Revision: 20240603
    • Publication Date:
      20240603
    • Accession Number:
      PMC11140475
    • Accession Number:
      10.1016/j.neuropsychologia.2024.108852
    • Accession Number:
      38508374