Suppression of sleepiness in drivers: combination of caffeine with a short nap.

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  • Author(s): Reyner LA;Reyner LA; Horne JA
  • Source:
    Psychophysiology [Psychophysiology] 1997 Nov; Vol. 34 (6), pp. 721-5.
  • Publication Type:
    Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • Language:
  • Additional Information
    • Source:
      Publisher: Blackwell Country of Publication: United States NLM ID: 0142657 Publication Model: Print Cited Medium: Print ISSN: 0048-5772 (Print) Linking ISSN: 00485772 NLM ISO Abbreviation: Psychophysiology Subsets: MEDLINE
    • Publication Information:
      Publication: Malden, MA : Blackwell
      Original Publication: Baltimore, Williams & Wilkins.
    • Subject Terms:
    • Abstract:
      Previous research has shown that caffeine and a < 15-min nap effectively and separately reduce sleepiness in drivers for 1 hr. In the present study, we examined in 12 sleepy individuals the treatments combined, taken during a 30-min break, prior to a longer (2 hr) continuous monotonous afternoon drive in a car simulator. Nonnap comparisons were 200 mg caffeine only and placebo. For placebo, driving incidents, subjective and electroencephalographic measures of sleepiness all reflected a mid-afternoon peak. This peak was significantly reduced by caffeine and eliminated by the combined treatment, which reduced incidents to 9% of placebo levels versus 34% of placebo levels for caffeine alone. Naps comprising "nonsleep dozing" were still effective.
    • Accession Number:
      0 (Central Nervous System Stimulants)
      3G6A5W338E (Caffeine)
    • Publication Date:
      Date Created: 19971224 Date Completed: 19980130 Latest Revision: 20190831
    • Publication Date:
    • Accession Number:
    • Accession Number: