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Computational modeling of the human atrial anatomy and electrophysiology.
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- Author(s): Dössel, Olaf; Krueger, Martin; Weber, Frank; Wilhelms, Mathias; Seemann, Gunnar
- Source:
Medical & Biological Engineering & Computing. Aug2012, Vol. 50 Issue 8, p773-799. 27p. 3 Diagrams, 3 Charts, 3 Graphs. - Source:
- Additional Information
- Subject Terms:
- Abstract: This review article gives a comprehensive survey of the progress made in computational modeling of the human atria during the last 10 years. Modeling the anatomy has emerged from simple 'peanut'-like structures to very detailed models including atrial wall and fiber direction. Electrophysiological models started with just two cellular models in 1998. Today, five models exist considering e.g. details of intracellular compartments and atrial heterogeneity. On the pathological side, modeling atrial remodeling and fibrotic tissue are the other important aspects. The bridge to data that are measured in the catheter laboratory and on the body surface (ECG) is under construction. Every measurement can be used either for model personalization or for validation. Potential clinical applications are briefly outlined and future research perspectives are suggested. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Medical & Biological Engineering & Computing is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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