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Phone: (843) 805-6930
West Ashley Library
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Clinical application of protein biomarkers in lupus erythematosus and lupus nephritis.
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- Author(s): Qi, S.; Chen, Q.; Xu, D.; Xie, N.; Dai, Y.
- Source:
Lupus; Sep2018, Vol. 27 Issue 10, p1582-1590, 9p, 1 Diagram, 1 Chart- Subject Terms:
- Source:
- Additional Information
- Abstract: Systemic lupus erythematosus (SLE) is a type of autoimmune disease that damages multiple organs, including the heart, joints, liver and kidneys. The main characteristics of SLE are the deposition of circulating autoantibodies; autoantigen complexes in the renal system; and abnormal expression of complements, cytokines and chemokines. Lupus nephritis (LN) is the most serious manifestation of SLE and is characterized by inflammation of the kidney. This review summarizes recent clinical applications of protein biomarkers including autoantibodies, complements, cytokines and chemokines and some new protein biomarkers in SLE and LN. The clinical differential diagnois of protein biomarkers related to prognosis and diagnosis is discussed and highlighted. Protein biomarkers play crucial roles in the study of SLE and LN. Useful biomarkers will provide insights into effective treatments for these diseases. Lupus (2018) 27, 1582-1590. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Lupus is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Abstract:
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