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Phone: (843) 805-6930
West Ashley Library
9 a.m. - 4 p.m.
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Folly Beach Library
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Phone: (843) 588-2001
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9 a.m. - 6 p.m.
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St. Paul's/Hollywood Library
9 a.m. - 5 p.m.
Phone: (843) 889-3300
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Effective use of pre-exposure prophylaxis (PrEP) Among stimulant users with multiple condomless sex partners: a longitudinal study of men who have sex with men in Los Angeles.
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- Author(s): Goodman-Meza, David; Beymer, Matthew R.; Kofron, Ryan M.; Amico, K. Rivet; Psaros, Christina; Bushman, Lane R.; Anderson, Peter L.; Bolan, Robert; Jordan, Wilbert C.; Rooney, James F.; Wohl, Amy R.; Landovitz, Raphael J.
- Source:
AIDS Care; Oct2019, Vol. 31 Issue 10, p1228-1233, 6p, 2 Charts, 1 Graph- Subject Terms:
SUBSTANCE abuse prevention; ATTITUDE (Psychology); BLOOD testing; CONDOMS; CONFIDENCE intervals; DRUG prescribing; LONGITUDINAL method; MEDICAL personnel; PREVENTIVE medicine; PATIENT compliance; PHOSPHATES; PHYSICIAN practice patterns; PSYCHOSOCIAL factors; TREATMENT effectiveness; PSYCHOLOGY of drug abusers; MEN who have sex with men; TENOFOVIR; SEXUAL partners; ODDS ratio - Source:
- Additional Information
- Subject Terms:
- Abstract: PrEP's potential benefit for men who have sex with men (MSM) who use stimulants may be limited by adherence or prescriber willingness to recommend PrEP due to concerns of non-compliance. Using data from PATH-PrEP, a 48-week study evaluating PrEP for MSM in Los Angeles, we modeled an interaction between stimulant use and condomless sex with multiple partners (CAS-MP) on prevention-effective dried blood spot tenofovir-diphosphate concentrations. At week 4, participants reporting stimulant use and CAS-MP had a decreased odds of prevention-effective adherence compared to non-stimulant use and non-CAS-MP (AOR 0.15, 95% CI 0.04–0.57). From week 4–48, participants reporting stimulant use and CAS-MP had increased odds of prevention-effective adherence (AOR 1.06 per week, 95%CI 1.01–1.12). Participants reporting CAS-MP without stimulant use had no significant change in prevention-effective adherence (AOR 0.99 per week, 95%CI 0.96–1.02). Stimulant use moderated the association of CAS-MP on prevention-effective PrEP adherence over time. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of AIDS Care is the property of Routledge and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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