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Effects of green tea consumption on glycemic control: a systematic review and meta-analysis of randomized controlled trials.
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- Author(s): Xu, Renfan; Bai, Yang; Yang, Ke; Chen, Guangzhi
- Source:
Nutrition & Metabolism; 7/10/2020, Vol. 17 Issue 1, p1-13, 13p, 1 Diagram, 4 Charts, 4 Graphs- Subject Terms:
BLOOD sugar; CONFIDENCE intervals; DIETARY supplements; FASTING; GLYCOSYLATED hemoglobin; INFORMATION storage & retrieval systems; MEDICAL databases; MEDICAL information storage & retrieval systems; INSULIN; MEDLINE; META-analysis; ONLINE information services; SYSTEMATIC reviews; GREEN tea; TREATMENT effectiveness; GLYCEMIC control - Source:
- Additional Information
- Abstract: Background: The results of human clinical trials investigating the effects of green tea on glycemic control are inconsistent. Methods: We conducted a systematic review and meta-analysis of RCTs that examined the effects of green tea supplementation on glycemic control. A literature search in PubMed, Embase, and Cochrane Library databases for RCTs that investigated the effect of green tea consumption on glycemic control was performed up to February 2020. A random-effects model was used to estimate weighted mean difference (WMD) with 95% confidence intervals (CIs). Results: Twenty-seven trials involving 2194 subjects were included in the meta-analysis. The pooled results showed that green tea significantly lowered fasting blood glucose by − 1.44 mg/dL (95%CI:-2.26, − 0.62 mg/dL; P < 0.001) with no obvious heterogeneity (I2 = 7.7%). However, green tea consumption did not significantly affect fasting insulin and HbA1c values. The mean differences were − 0.46μIU/mL (95% CI: − 1.10, 0.17μIU/mL; P = 0.21) for fasting insulin and − 0.06%; (95% CI: − 0.12, 0.01%; P = 0.07) for HbA
1c concentrations. Heterogeneity was significant in fasting insulin (I2 = 46.8%) and mild in HbA1c (I2 = 1.7%). Conclusions: In short-term trials, green tea supplementation significantly reduced fasting glucose, but had no significant effect on fasting insulin and HbA1c . Long-term trials assessing the effects of green tea supplementation on glycemic control are needed. [ABSTRACT FROM AUTHOR] - Abstract: Copyright of Nutrition & Metabolism is the property of BioMed Central and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Abstract:
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