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Diet quality and cardiometabolic health in childhood: the Generation R Study.
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- Author(s): Siddiqui, Noreen Z.; Nguyen, Anh N.; Santos, Susana; Voortman, Trudy
- Source:
European Journal of Nutrition; Mar2022, Vol. 61 Issue 2, p729-736, 8p, 1 Diagram, 2 Charts- Subject Terms:
CARDIOVASCULAR diseases risk factors; TRIGLYCERIDES; HDL cholesterol; LIFESTYLES; CONFIDENCE intervals; SYSTOLIC blood pressure; MULTIPLE regression analysis; INGESTION; NUTRITIONAL requirements; INSULIN; SOCIOECONOMIC factors; QUESTIONNAIRES; DESCRIPTIVE statistics; FOOD quality; BODY mass index; LONGITUDINAL method; ADIPOSE tissues - Source:
- Additional Information
- Subject Terms:
- Abstract: Purpose: Diet is an important determinant of cardiometabolic disease risk in adults. We aimed to study associations of diet quality with cardiometabolic health in school-age children. Methods: This study was embedded in the Generation R Study a prospective population-based cohort in Rotterdam, the Netherlands and included 3991 children. Food intake was assessed with a Food-Frequency Questionnaire at age 8 years. A diet quality score (0–10) was calculated reflecting adherence to age-specific dietary guidelines. The following outcome variables were measured at age 10 years and used to create a continuous cardiometabolic risk factor score: body fat percentage, insulin, triglycerides, HDL cholesterol, and systolic and diastolic blood pressure. Outcomes were expressed in age- and sex-specific standard deviation scores (SDS). Multivariable linear regression models were used to assess associations between the diet quality score and the cardiometabolic risk factor score and with the individual cardiometabolic risk factors. Results: In models adjusted for socioeconomic and lifestyle factors and BMI, a higher diet quality was associated with a lower cardiometabolic risk factor score [− 0.08 per point higher diet score, (95% CI − 0.15, − 0.001)]. This association was mainly driven by associations of higher diet quality with lower systolic [− 0.04 SD (95% CI − 0.06, − 0.01)] and diastolic blood pressure [− 0.05 SD, (95% CI − 0.07, − 0.02)]. No statistically significant associations were found for insulin, triglycerides, HDL cholesterol, or body fat percentage as individual factors. Conclusions: We found an association between higher diet quality and better cardiometabolic health in childhood, mainly driven by a lower blood pressure. Further research is needed to explore associations of diet quality in childhood with long-term cardiometabolic health. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of European Journal of Nutrition is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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