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Carbohydrates Used in Polymeric Systems for Drug Delivery: From Structures to Applications.
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- Author(s): Di, Xiangjie; Liang, Xiao; Shen, Chao; Pei, Yuwen; Wu, Bin; He, Zhiyao
- Source:
Pharmaceutics; Apr2022, Vol. 14 Issue 4, pN.PAG-N.PAG, 23p- Subject Terms:
- Source:
- Additional Information
- Abstract: Carbohydrates, one of the most important compounds in living organisms, perform numerous roles, including those associated with the extracellular matrix, energy-related compounds, and information. Of these, polymeric carbohydrates are a class of substance with a long history in drug delivery that have attracted more attention in recent years. Because polymeric carbohydrates have the advantages of nontoxicity, biocompatibility, and biodegradability, they can be used in drug targeting, sustained drug release, immune antigens and adjuvants. In this review, various carbohydrate-based or carbohydrate-modified drug delivery systems and their applications in disease therapy have been surveyed. Specifically, this review focuses on the fundamental understanding of carbohydrate-based drug delivery systems, strategies for application, and the evaluation of biological activity. Future perspectives, including opportunities and challenges in this field, are also discussed. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Pharmaceutics is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Abstract:
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