New molecular entities: Tekturna.

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    • Abstract:
      The article reports on the approval of aliskiren, an oral renin inhibitor for the treatment of hypertension. Aliskiren is approved by the U.S. Food & Drug Administration on March 5, 2007 as monotherapy or in combination with other antihypertensive agents. The efficacy of aliskiren monotherapy has been tested in patients with mild-to-moderate hypertension for eight weeks in clinical trial. The starting dosage of aliskiren is recommended to be 150 milligrams per day.