Anti-Epidermal Growth Factor Receptor Strategies for Advanced Breast Cancer.

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    • Abstract:
      The article reviews some present data concerning tyrosine kinase inhibitors in relation to the management of advanced breast cancer. It highligts on the understanding of the molecular mechanisms of these agents involved with a balanced with the application of the agents to the clinical practice. It discusses the epidermal growth factor and ligands, epidermal growth factor receptor, ligand receptor interactions, among others.