Urea inhibits Na-K-2Cl cotransport in medullary thick ascending limb cells.

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    • Abstract:
      Investigates the effect of physiological concentration of urea on sodium-potassium-2chloride (Na-K-2Cl) cotransport in medullary thick ascending limb cells. Regulation of Na-K-2Cl activity by cotransport protein or regulatory protein phosphorylation; Influence of the presence of urea on the number of [3H]bumetanide binding sites and functioning cotransport sites.