Evaluation of a Records-Review Surveillance System Used to Determine the Prevalence of Autism Spectrum Disorders

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  • Author(s): Avchen, Rachel Nonkin; Wiggins, Lisa D.; Devine, Owen
  • Language:
    English
  • Source:
    Journal of Autism and Developmental Disorders. Feb 2011 41(2):227-236.
  • Physical Description:
    PDF
  • Publication Date:
    2011
  • Document Type:
    Journal Articles
    Reports - Research
  • Additional Information
    • Availability:
      Springer. 233 Spring Street, New York, NY 10013. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-348-4505; e-mail: [email protected]; Web site: http://www.springerlink.com
    • Peer Reviewed:
      Y
    • Source:
      10
    • Subject Terms:
      Autism; Classification; Evaluation; Pervasive Developmental Disorders; Children; Sensitivity Training; Heterogeneous Grouping
    • Accession Number:
      10.1007/s10803-010-1050-7
    • ISSN:
      0162-3257
    • Abstract:
      We conducted the first study that estimates the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of a population-based autism spectrum disorders (ASD) surveillance system developed at the Centers for Disease Control and Prevention. The system employs a records-review methodology that yields ASD classification (case versus non-ASD case) and was compared with classification based on clinical examination. The study enrolled 177 children. Estimated specificity (0.96, [CI 0.95 = 0.94, 0.99]), PPV (0.79 [CI 0.95 = 0.66, 0.93]), and NPV (0.91 [CI 0.95 = 0.87, 0.96]) were high. Sensitivity was lower (0.60 [CI .95 = 0.45, 0.75]). Given diagnostic heterogeneity, and the broad array of ASD in the population, identifying children with ASD is challenging. Records-based surveillance yields a population-based estimate of ASD that is likely conservative.
    • Abstract:
      As Provided
    • Number of References:
      31
    • Publication Date:
      2011
    • Accession Number:
      EJ912250