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West Ashley Library
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Frequent Cannabis Use and Cessation of Injection of Opioids, Vancouver, Canada, 2005–2018.
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- Author(s): Reddon, Hudson (AUTHOR); DeBeck, Kora (AUTHOR); Socias, M. Eugenia (AUTHOR); Lake, Stephanie (AUTHOR); Dong, Huiru (AUTHOR); Karamouzian, Mohammad (AUTHOR); Hayashi, Kanna (AUTHOR); Kerr, Thomas (AUTHOR); Milloy, M-J (AUTHOR)
- Source:
American Journal of Public Health. Oct2020, Vol. 110 Issue 10, p1553-1560. 8p. - Source:
- Additional Information
- Subject Terms:
- Subject Terms:
- Abstract: Objectives. To evaluate the impact of frequent cannabis use on injection cessation and injection relapse among people who inject drugs (PWID). Methods. Three prospective cohorts of PWID from Vancouver, Canada, provided the data for these analyses. We used extended Cox regression analysis with time-updated covariates to analyze the association between cannabis use and injection cessation and injection relapse. Results. Between 2005 and 2018, at-least-daily cannabis use was associated with swifter rates of injection cessation (adjusted hazard ratio [AHR] = 1.16; 95% confidence interval [CI] = 1.03, 1.30). A subanalysis revealed that this association was only significant for opioid injection cessation (AHR = 1.26; 95% CI = 1.12, 1.41). At-least-daily cannabis use was not significantly associated with injection relapse (AHR = 1.08; 95% CI = 0.95, 1.23). Conclusions. We observed that at-least-daily cannabis use was associated with a 16% increase in the hazard rate of injection cessation, and this effect was restricted to the cessation of injection opioids. This finding is encouraging given the uncertainty surrounding the impact of cannabis policies on PWID during the ongoing opioid overdose crisis in many settings in the United States and Canada. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of American Journal of Public Health is the property of American Public Health Association and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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