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Main Library
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Does the migraine attack start in the cortex and is the cortex critical in the migraine process?
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- Author(s): Barbanti, Piero (AUTHOR); Fofi, Luisa (AUTHOR); Aurilia, Cinzia (AUTHOR); Egeo, Gabriella (AUTHOR)
- Source:
Neurological Sciences. May2019 Supplemetn 1, Vol. 40 Issue 1, p31-37. 7p. 1 Chart. - Source:
- Additional Information
- Subject Terms:
- Abstract: Migraine is a pure human neurovascular disorder with no reliable corresponding animal model. The cerebral cortex (CC) has long been discussed as a crucial element of its complex mechanism. The present review considers the state of the art of experimental evidence on the involvement of CC in migraine. An ample series of research data points to a role of CC in the migraine process, also at the beginning of the attack, especially in the form with aura. However, in spite of several CC, peculiarities emerged in experimental settings, the enigma on their significance (cause or consequence of the disease?) remains. All in all, we believe that pure clinical observations and reasoning, i.e., its exclusive human nature and the precipitating role of stress, are still the most persuasive cues supporting the CC involvement in migraine. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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