Cyclic AMP-regulated opposing and parallel effects of serotonin and dopamine on phototaxis in the Marmorkrebs (marbled crayfish).

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  • Additional Information
    • Subject Terms:
    • Abstract:
      Phototactic behaviours are observed from prokaryotes to amphibians and are a basic form of orientation. We showed that the marbled crayfish displays phototaxis in which the behavioural response reversed from negative to positive depending on external light conditions. Animals reared in a 12-L/12-D light cycle showed negative phototaxis during daytime and positive phototaxis during night-time. Animals reared under constant light conditioning showed negative phototaxis during day- and night-time, while animals reared under constant dark conditioning showed positive phototaxis during day- and night-time. Injection of serotonin leads to a reversal of negative to positive phototaxis in both light/dark-reared and light/light-reared animals while injection of dopamine induced reversed negative phototaxis in dark/dark-reared animals. Four hours of dark adaptation were enough for light/dark-reared animals to reverse phototaxis from negative to positive. Injection of a serotonin 5 HT1 receptor antagonist blocked the reverse phototaxis while serotonin 5 HT2 receptor antagonists had no effects. Similarly, dark/dark-reared animals reversed to showing negative phototaxis after 4 h of light adaptation. Injection of a dopamine DA1 receptor antagonist blocked this reverse phototaxis, while dopamine DA2 receptor antagonists had no effects. Injection of a cAMP analogue into light/dark-reared animals blocked reverse phototaxis after dark adaptation, while adenylate cyclase inhibitor in dark/dark-reared animals blocked reverse phototaxis after light adaptation. These results strongly suggest that serotonin mediates positive phototaxis owing to decreased cAMP levels, while dopamine-mediated negative phototaxis occurs due to increased cAMP levels. Supporting this, the ratio of serotonin to dopamine in the brain was much higher in dark/dark-reared than light/dark-reared animals. [ABSTRACT FROM AUTHOR]
    • Abstract:
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    • ISSN:
      0953-816X
    • Accession Number:
      10.1111/ejn.13632
    • Accession Number:
      124505107
  • Citations
    • ABNT:
      SHIRATORI, C. et al. Cyclic AMP-regulated opposing and parallel effects of serotonin and dopamine on phototaxis in the Marmorkrebs (marbled crayfish). European Journal of Neuroscience, [s. l.], v. 46, n. 3, p. 1863–1874, 2017. DOI 10.1111/ejn.13632. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=124505107. Acesso em: 6 jul. 2020.
    • AMA:
      Shiratori C, Suzuki N, Momohara Y, Shiraishi K, Aonuma H, Nagayama T. Cyclic AMP-regulated opposing and parallel effects of serotonin and dopamine on phototaxis in the Marmorkrebs (marbled crayfish). European Journal of Neuroscience. 2017;46(3):1863-1874. doi:10.1111/ejn.13632.
    • AMA11:
      Shiratori C, Suzuki N, Momohara Y, Shiraishi K, Aonuma H, Nagayama T. Cyclic AMP-regulated opposing and parallel effects of serotonin and dopamine on phototaxis in the Marmorkrebs (marbled crayfish). European Journal of Neuroscience. 2017;46(3):1863-1874. doi:10.1111/ejn.13632
    • APA:
      Shiratori, C., Suzuki, N., Momohara, Y., Shiraishi, K., Aonuma, H., & Nagayama, T. (2017). Cyclic AMP-regulated opposing and parallel effects of serotonin and dopamine on phototaxis in the Marmorkrebs (marbled crayfish). European Journal of Neuroscience, 46(3), 1863–1874. https://doi.org/10.1111/ejn.13632
    • Chicago/Turabian: Author-Date:
      Shiratori, Chihiro, Nanoka Suzuki, Yuto Momohara, Kyosuke Shiraishi, Hitoshi Aonuma, and Toshiki Nagayama. 2017. “Cyclic AMP-Regulated Opposing and Parallel Effects of Serotonin and Dopamine on Phototaxis in the Marmorkrebs (Marbled Crayfish).” European Journal of Neuroscience 46 (3): 1863–74. doi:10.1111/ejn.13632.
    • Harvard:
      Shiratori, C. et al. (2017) ‘Cyclic AMP-regulated opposing and parallel effects of serotonin and dopamine on phototaxis in the Marmorkrebs (marbled crayfish)’, European Journal of Neuroscience, 46(3), pp. 1863–1874. doi: 10.1111/ejn.13632.
    • Harvard: Australian:
      Shiratori, C, Suzuki, N, Momohara, Y, Shiraishi, K, Aonuma, H & Nagayama, T 2017, ‘Cyclic AMP-regulated opposing and parallel effects of serotonin and dopamine on phototaxis in the Marmorkrebs (marbled crayfish)’, European Journal of Neuroscience, vol. 46, no. 3, pp. 1863–1874, viewed 6 July 2020, .
    • MLA:
      Shiratori, Chihiro, et al. “Cyclic AMP-Regulated Opposing and Parallel Effects of Serotonin and Dopamine on Phototaxis in the Marmorkrebs (Marbled Crayfish).” European Journal of Neuroscience, vol. 46, no. 3, Aug. 2017, pp. 1863–1874. EBSCOhost, doi:10.1111/ejn.13632.
    • Chicago/Turabian: Humanities:
      Shiratori, Chihiro, Nanoka Suzuki, Yuto Momohara, Kyosuke Shiraishi, Hitoshi Aonuma, and Toshiki Nagayama. “Cyclic AMP-Regulated Opposing and Parallel Effects of Serotonin and Dopamine on Phototaxis in the Marmorkrebs (Marbled Crayfish).” European Journal of Neuroscience 46, no. 3 (August 2017): 1863–74. doi:10.1111/ejn.13632.
    • Vancouver/ICMJE:
      Shiratori C, Suzuki N, Momohara Y, Shiraishi K, Aonuma H, Nagayama T. Cyclic AMP-regulated opposing and parallel effects of serotonin and dopamine on phototaxis in the Marmorkrebs (marbled crayfish). European Journal of Neuroscience [Internet]. 2017 Aug [cited 2020 Jul 6];46(3):1863–74. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=124505107