Evaluation of Appetite-Regulating Hormones ın Young Children with Autism Spectrum Disorder.

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  • Additional Information
    • Subject Terms:
      AUTISM; COMPARATIVE studies; ENZYME-linked immunosorbent assay; NEUROPEPTIDES; LEPTIN; GHRELIN; CHILDREN
    • Subject Terms:
      TURKEY
    • Abstract:
      This study aimed to investigate the role of leptin, ghrelin, neuropeptide Y, and nesfatin-1 in young children with autism spectrum disorder (ASD). A total of 44 children with ASD and 44 healthy controls aged 18–60 months were included. Plasma levels of hormones were measured using commercial enzyme-linked immunosorbent assay kits. Plasma leptin and ghrelin levels were significantly higher in the ASD group than in the control group. However, no significant difference for plasma neuropeptide Y and nesfatin-1 levels was detected between the groups. No relation was found between the severity of ASD symptoms, severity of eating problems, and plasma levels of hormones. Leptin and ghrelin may play a potential role in the pathogenesis of ASD. [ABSTRACT FROM AUTHOR]
    • Abstract:
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