Locking down tetanus.

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  • Additional Information
    • Subject Terms:
      TETANUS; ANAEROBIC infections; CLOSTRIDIUM diseases; IMMUNIZATION; SPASMS; BACTERIAL diseases
    • Abstract:
      Caused by the anaerobic, sporeproducing Clostridium tetani bacterium, tetanus is an acute and potentially fatal disease that usually originates in a wound. Common in soil, C. tetani spores may also be found in the intestinal tracts of humans and animals. However, tetanus is rare in the U.S. today. Wound cultures for C. tetani are unreliable because the bacterium is recoverable from only about 30% of infected wounds, and C. tetani is sometimes recovered from patients spores, and administration of tetanus immune globulin to help remove unbound endotoxin. Preventing disease Fortunately tetanus is completely preventable through vaccination.