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Lamiaceae: una revisión sobre sus efectos neurofarmacológicos y su presencia en Cuba.
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- Author(s): de la Caridad Sierra-Pérez, Roxana1 ; González-Canavaciolo, Víctor Luis1; Marrero-Delange, David1; Rodríguez-Leyes, Eduardo Antonio1
- Source:
Revista CENIC Ciencias Biologicas. ene-abr2013, Vol. 44 Issue 1, p17-33. 17p. - Source:
- Additional Information
- Subject Terms:
- Abstract: Since ancient times the Lamiaceae have been used to treat several disorders, including those related to the Central Nervous System. Consequently, extensive research on the neuropharmacological effects of various genera of this family has been conducted. Among them, Origanum, Ocimum, Mentha, Salvia, Scutellaria, Plectranthus, and Melissa have been the most studied. This paper is intended to briefly summarize their main ethnomedical uses and the demonstrated neuropharmacological effects of the family Lameaceae as well as to offer a glance on the occurrence of these plants in Cuba. In such regard, the anxiolytic and/or antidepressant effects for Ocimum, Salvia, Scutellaria, Plectranthus, Melissa and Origanum; the neuroprotective properties for Ocimum, Mentha, Scutellaria, Melissa and Origanum; and the anticonvulsant effects for Salvia and Plectranthus have been described. Salvia is the most used and studied genus of Lamiaceae, due to its sedative, hypnotic, analgesic, anti-parkinsonian and memory-improvement properties. This last property is very interesting and promising, regarding its potential use for dementia, one of the main causes of cerebrovascular morbidity and mortality. Among the chemical structures that may support the effects of the Lamiaceae on the Central Nervous System, polyphenols (mainly flavonoids) and mono and diterpenes seem to account for most of them. [ABSTRACT FROM AUTHOR]
- Abstract: Desde tiempos remotos las Lamiaceae han sido utilizadas en el tratamiento de diferentes enfermedades, incluidas aquellas relacionadas con el sistema nervioso central. Consecuentemente, se han realizado exhaustivas investigaciones sobre los efectos neurofarmacológicos de varias especies de esta familia. Entre estas, las más estudiadas pertenecen a los géneros Origanum, Ocimum, Mentha, Salvia, Scutellaria, Plectranthus y Melissa. Este trabajo pretende ofrecer resumidamente los principales usos etnomédicos y los efectos neurofarmacológicos demostrados de la familia Lamiaceae, así como brindar una mirada sobre la presencia de estas plantas en Cuba. En este sentido, se han descrito efectos ansiolíticos o antidepresivos o ambos para especies de los géneros Ocimum, Salvia, Scutellaria, Plectranthus, Melissa y Origanum; propiedades neuroprotectoras para especies de los géneros Ocimum, Mentha, Scutellaria, Melissa y Origanum; y efecto anticonvulsivante para especies de Salvia y Plectranthus. Salvia es el género de esta familia que ha sido más empleado y estudiado por sus propiedades sedativas, hipnóticas, analgésicas, antiparquisonianas y en el mejoramiento de la memoria, efecto interesante y promisorio por su uso potencial en la demencia, una de las principales causas de morbilidad y mortalidad cerebrovascular. Entre las estructuras químicas que pudieran ser responsables de los efectos de las Lamiaceae sobre el sistema nervioso central están los polifenoles (principalmente flavonoides) y los mono y diterpenos. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Revista CENIC Ciencias Biologicas is the property of Centro Nacional de Investigaciones Cientificas and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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