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Academic Journal

PARK2 promotes mitochondrial pathway of apoptosis and antimicrotubule drugs chemosensitivity via degradation of phospho-BCL-2.

  • Authors : Chen H; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.; Li Y

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*physiology ; Microtubules/Microtubules/Microtubules/*drug effects

  • Source: Theranostics [Theranostics] 2020 Aug 08; Vol. 10 (22), pp. 9984-10000. Date of Electronic Publication: 2020 Aug 08 (Print Publication: 2020).Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101552395 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Apoptotic Effects of a Thioether Analog of Vitamin K 3 in a Human Leukemia Cell Line.

  • Authors : Asami S; Laboratory of Clinical Medicine, 12976Nihon University School of Pharmacy, Chiba, Japan.; Suzuki M

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Jurkat Cells/Jurkat Cells/Jurkat Cells/*drug effects

  • Source: International journal of toxicology [Int J Toxicol] 2021 Dec; Vol. 40 (6), pp. 517-529. Date of Electronic Publication: 2021 Oct 06.Publisher: Sage Publications Country of Publication: United States NLM ID: 9708436 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Pharmacological Inhibition of CDK8 in Triple-Negative Breast Cancer Cell Line MDA-MB-468 Increases E2F1 Protein, Induces Phosphorylation of STAT3 and Apoptosis.

  • Authors : Spear JM; Department of Pharmaceutics and Medicinal Chemistry, Thomas J. Long School of Pharmacy, University of the Pacific, Stockton, CA 95211, USA.; Lu Z

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Cyclin-Dependent Kinase 8/Cyclin-Dependent Kinase 8/Cyclin-Dependent Kinase 8/*metabolism

  • Source: Molecules (Basel, Switzerland) [Molecules] 2020 Dec 04; Vol. 25 (23). Date of Electronic Publication: 2020 Dec 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Difluoromethylornithine Induces Apoptosis through Regulation of AP-1 Signaling via JNK Phosphorylation in Epithelial Ovarian Cancer.

  • Authors : Hwang WY; Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam 13620, Korea.; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul 03080, Korea.

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Carcinoma, Ovarian Epithelial/Carcinoma, Ovarian Epithelial/Carcinoma, Ovarian Epithelial/*drug therapy ; Eflornithine/Eflornithine/Eflornithine/*pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Sep 23; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

CaMKII-dependent ryanodine receptor phosphorylation mediates sepsis-induced cardiomyocyte apoptosis.

  • Authors : Sepúlveda M; Centro de Investigaciones Cardiovasculares, Conicet La Plata, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, La Plata, Argentina.; Burgos JI

Subjects: Apoptosis/Apoptosis/Apoptosis/*physiology ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/Calcium-Calmodulin-Dependent Protein Kinase Type 2/Calcium-Calmodulin-Dependent Protein Kinase Type 2/*metabolism ; Myocytes, Cardiac/Myocytes, Cardiac/Myocytes, Cardiac/*metabolism

  • Source: Journal of cellular and molecular medicine [J Cell Mol Med] 2020 Sep; Vol. 24 (17), pp. 9627-9637. Date of Electronic Publication: 2020 Jul 24.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Cationic Pillar[6]arene Induces Cell Apoptosis by Inhibiting Protein Tyrosine Phosphorylation Via Host-Guest Recognition.

  • Authors : Li CP; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China.; Lu YX

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Phosphorylation/Phosphorylation/Phosphorylation/*drug effects

  • Source: International journal of molecular sciences [Int J Mol Sci] 2020 Jul 15; Vol. 21 (14). Date of Electronic Publication: 2020 Jul 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

AMPK activation induced by promethazine increases NOXA expression and Beclin-1 phosphorylation and drives autophagy-associated apoptosis in chronic myeloid leukemia.

  • Authors : Medeiros HCD; Center for Natural and Human Sciences (CCNH), Federal University of ABC (UFABC), Santo André, SP, Brazil.; Colturato-Kido C

Subjects: AMP-Activated Protein Kinases/AMP-Activated Protein Kinases/AMP-Activated Protein Kinases/*metabolism ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Autophagy/Autophagy/Autophagy/*drug effects

  • Source: Chemico-biological interactions [Chem Biol Interact] 2020 Jan 05; Vol. 315, pp. 108888. Date of Electronic Publication: 2019 Nov 02.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786

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Academic Journal

Arctiin is a pharmacological inhibitor of STAT3 phosphorylation at tyrosine 705 residue and potentiates bortezomib-induced apoptotic and anti-angiogenic effects in human multiple myeloma cells.

  • Authors : Lee JH; College of Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, South Korea.; Kim C

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Cell Proliferation/Cell Proliferation/Cell Proliferation/*drug effects ; Furans/Furans/Furans/*pharmacology

  • Source: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2019 Mar 01; Vol. 55, pp. 282-292. Date of Electronic Publication: 2018 Aug 11.Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Phosphorylation drives an apoptotic protein to activate antiapoptotic genes: paradigm of influenza A matrix 1 protein function.

  • Authors : Halder UC; Division of Virology, National Institute of Cholera and Enteric Diseases, P-33 C.I.T. Road, Scheme-XM, Beliaghata, Kolkata 700010, India.; Bhowmick R

Subjects: Apoptosis* ; Gene Expression Regulation, Viral*; Phosphorylation/Phosphorylation/Phosphorylation/*physiology

  • Source: The Journal of biological chemistry [J Biol Chem] 2013 May 17; Vol. 288 (20), pp. 14554-14568. Date of Electronic Publication: 2013 Apr 02.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Angiotensin-Converting Enzyme 2 Inhibits Apoptosis of Pulmonary Endothelial Cells During Acute Lung Injury Through Suppressing SMAD2 Phosphorylation.

  • Authors : Ji Y; Department of Respiratory medicine, First people's Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China.; Gao F

Subjects: Acute Lung Injury/Acute Lung Injury/Acute Lung Injury/*metabolism ; Apoptosis/Apoptosis/Apoptosis/*physiology ; Endothelial Cells/Endothelial Cells/Endothelial Cells/*metabolism

  • Source: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology [Cell Physiol Biochem] 2015; Vol. 35 (6), pp. 2203-12. Publisher: Cell Physiol Biochem Press GmbH & Co KG Country of Publication: Germany NLM ID: 9113221 Publication Model: Print-Electronic Cited Medium:

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