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The Machado-Joseph Disease Deubiquitinase Ataxin-3 Regulates the Stability and Apoptotic Function of p53.

• Authors : Liu H; State Key Laboratory of Membrane Biology, Institute of Zoology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, China.; Li X

Subjects: Apoptosis*; Ataxin-3/Ataxin-3/Ataxin-3/*metabolism ; Machado-Joseph Disease/Machado-Joseph Disease/Machado-Joseph Disease/*enzymology

• Source: PLoS biology [PLoS Biol] 2016 Nov 16; Vol. 14 (11), pp. e2000733. Date of Electronic Publication: 2016 Nov 16 (Print Publication: 2016).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet

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Agricola

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SUMO-1 Modification on K166 of PolyQ-Expanded aTaxin-3 Strengthens Its Stability and Increases Its Cytotoxicity.

• Authors : Ya-Fang Zhou; Shu-Sheng Liao; Ying-Ying Luo

Subjects: CYTOTOXIC T cells; NEURODEGENERATION; SPINOCEREBELLAR ataxia

• Source: PLoS ONE; Jan2013, Vol. 8 Issue 1, Special section p1-9, 9p

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Ataxin-3, DNA Damage Repair, and SCA3 Cerebellar Degeneration: On the Path to Parsimony?

• Authors : Ward, Jacqueline M.; La Spada, Albert R.

Subjects: SPINOCEREBELLAR ataxia; NUCLEIC acids; ATAXIA

• Source: PLoS Genetics; Jan2015, Vol. 11 Issue 1, p1-4, 4p

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Tissue-Specific Vulnerability to Apoptosis in Machado-Joseph Disease.

• Authors : Ferreira, Ana F.; Raposo, Mafalda; Shaw, Emily D.

Subjects: POSTMORTEM changes; DENTATE nucleus; GENE expression profiling

• Source: Cells (2073-4409); May2023, Vol. 12 Issue 10, p1404, 16p

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Absence of ataxin-3 leads to cytoskeletal disorganization and increased cell death.

• Authors : Rodrigues AJ; Life and Health Sciences Research Institute, University of Minho, Braga, Portugal.; do Carmo Costa M

Subjects: Apoptosis/Apoptosis/Apoptosis/*physiology ; Cytoskeleton/Cytoskeleton/Cytoskeleton/*metabolism ; Nerve Tissue Proteins/Nerve Tissue Proteins/Nerve Tissue Proteins/*physiology

• Source: Biochimica et biophysica acta [Biochim Biophys Acta] 2010 Oct; Vol. 1803 (10), pp. 1154-63. Date of Electronic Publication: 2010 Jul 15.Publisher: Elsevier Pub. Co Country of Publication: Netherlands NLM ID: 0217513 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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A neuroendocrine dysfunction, not testicular mutant ataxin-3 cleavage fragment or aggregate, causes cell death in testes of transgenic mice.

• Authors : Colomer Gould VF; Goti D; Kiluk J

Subjects: Apoptosis*; Gonadotropins, Pituitary/Gonadotropins, Pituitary/Gonadotropins, Pituitary/*blood ; Nerve Tissue Proteins/Nerve Tissue Proteins/Nerve Tissue Proteins/*genetics

• Source: Cell death and differentiation [Cell Death Differ] 2006 Mar; Vol. 13 (3), pp. 524-6.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print Cited Medium: Print ISSN: 1350-9047

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Polyglutamine-expanded ataxin-3 activates mitochondrial apoptotic pathway by upregulating Bax and downregulating Bcl-xL.

• Authors : Chou AH; Department of Anesthesiology, Chang Gung Memorial Hospital, Taiwan, ROC.; Yeh TH

Subjects: Apoptosis/Apoptosis/Apoptosis/*physiology ; Mitochondria/Mitochondria/Mitochondria/*metabolism ; Nerve Tissue Proteins/Nerve Tissue Proteins/Nerve Tissue Proteins/*metabolism

• Source: Neurobiology of disease [Neurobiol Dis] 2006 Feb; Vol. 21 (2), pp. 333-45. Date of Electronic Publication: 2005 Aug 19.Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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Full-length expanded ataxin-3 enhances mitochondrial-mediated cell death and decreases Bcl-2 expression in human neuroblastoma cells.

• Authors : Tsai HF; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC.; Tsai HJ

Subjects: Apoptosis* ; Trinucleotide Repeat Expansion*; Machado-Joseph Disease/Machado-Joseph Disease/Machado-Joseph Disease/*genetics

• Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2004 Nov 26; Vol. 324 (4), pp. 1274-82.Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print Cited Medium: Print ISSN: 0006-291X (Print)

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The role of deubiquitinating enzymes in apoptosis.

• Authors : Ramakrishna S; Department of Biomedical Science, CHA General Hospital, CHA University, 606-16 Yeoksam 1-Dong, Gangnam-Gu, Seoul, 135-081, Republic of Korea.; Suresh B

Subjects: Apoptosis* ; Ubiquitination*; Ubiquitin/Ubiquitin/Ubiquitin/*metabolism

• Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2011 Jan; Vol. 68 (1), pp. 15-26. Date of Electronic Publication: 2010 Aug 21.Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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