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Astrocyte-specific DJ-1 overexpression protects against rotenone-induced neurotoxicity in a rat model of Parkinson's disease.

• Authors : De Miranda BR; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, United States; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, United States.

Subjects: Astrocytes/Astrocytes/Astrocytes/*metabolism ; Insecticides/Insecticides/Insecticides/*toxicity ; Parkinsonian Disorders/Parkinsonian Disorders/Parkinsonian Disorders/*metabolism

• Source: Neurobiology of disease [Neurobiol Dis] 2018 Jul; Vol. 115, pp. 101-114. Date of Electronic Publication: 2018 Apr 09.Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson's disease model.

• Authors : Morrone Parfitt, Gustavo; Coccia, Elena; Goldman, Camille

Subjects: PARKINSON'S disease; RECEPTOR for advanced glycation end products (RAGE); ADVANCED glycation end-products

• Source: Nature Communications; 1/10/2024, Vol. 15 Issue 1, p1-17, 17p

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Astragaloside IV inhibits experimental autoimmune encephalomyelitis by modulating the polarization of both microglia/macrophages and astrocytes.

• Authors : Jingwen Yu; Bingtao Mu; Minfang Guo

• Source: Folia Neuropathologica; 2023, Vol. 61 Issue 3, p273-290, 18p

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Transcriptomic-based evaluation of trichloroethylene glutathione and cysteine conjugates demonstrate phenotype-dependent stress responses in a panel of human in vitro models.

• Authors : Capinha, Liliana; Zhang, Yaran; Holzer, Anna-Katharina

Subjects: CYSTEINE; INDUCED pluripotent stem cells; UNFOLDED protein response

• Source: Archives of Toxicology; Feb2023, Vol. 97 Issue 2, p523-545, 23p

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Astrocytes and Microglia in Stress-Induced Neuroinflammation: The African Perspective.

• Authors : Olude, Matthew Ayokunle; Mouihate, Abdeslam; Mustapha, Oluwaseun Ahmed

Subjects: ASTROCYTES; MICROGLIA; NEURAL developmentAFRICA

• Source: Frontiers in Immunology; 5/30/2022, Vol. 13, p1-17, 17p

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Astrocyte dysfunction in Parkinson's disease: from the perspectives of transmitted α-synuclein and genetic modulation.

• Authors : Wang, Changjing; Yang, Tongtong; Liang, Meiyu

Subjects: PARKINSON'S disease; NEUROGLIA; GENETIC mutation

• Source: Translational Neurodegeneration; 10/18/2021, Vol. 10 Issue 1, p1-17, 17p

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Simvastatin Prevents Neurodegeneration in the MPTP Mouse Model of Parkinson's Disease via Inhibition of A1 Reactive Astrocytes.

• Authors : Du, Ren-Wei; Bu, Wen-Guang

• Source: Neuroimmunomodulation; 2021, Vol. 28 Issue 2, p82-89, 8p

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Cellular selectivity of AAV serotypes for gene delivery in neurons and astrocytes by neonatal intracerebroventricular injection.

• Authors : Hammond, Sean L.; Leek, Ashley N.; Richman, Evan H.

Subjects: BRAIN disease treatment; GENE delivery techniques; NEURONS

• Source: PLoS ONE; 12/15/2017, Vol. 12 Issue 12, p1-22, 22p

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Microglia amplify inflammatory activation of astrocytes in manganese neurotoxicity.

• Authors : Kirkley, Kelly S.; Popichak, Katriana A.; Afzali, Maryam F.

Subjects: MICROGLIA; PARKINSON'S disease treatment; ALZHEIMER'S disease treatment

• Source: Journal of Neuroinflammation; 5/5/2017, Vol. 14, p1-17, 17p

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Curcumin exerts anti-inflammatory and antioxidative properties in 1-methyl-4-phenylpyridinium ion (MPP)-stimulated mesencephalic astrocytes by interference with TLR4 and downstream signaling pathway.

• Authors : Yu, Song; Wang, Xu; He, Xingliang

• Source: Cell Stress & Chaperones; Jul2016, Vol. 21 Issue 4, p697-705, 9p

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