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Editorial & Opinion

The drug titration paradox: something obvious finally understood.

  • Authors : Egan TD; Department of Anesthesiology, University of Utah School of Medicine, Salt Lake City, UT, USA. Electronic address: .

Subjects: Dose-Response Relationship, Drug*; Humans

  • Source: British journal of anaesthesia [Br J Anaesth] 2022 Jun; Vol. 128 (6), pp. 900-902. Date of Electronic Publication: 2022 Apr 07.Publisher: Elsevier Country of Publication: England NLM ID: 0372541 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

EDP-305 in patients with NASH: A phase II double-blind placebo-controlled dose-ranging study.

  • Authors : Ratziu V; Sorbonne Université, ICAN, Hospital Pitié-Salpêtrière, INSERM UMRS 1138 CRC, Paris, France.; Rinella ME

Subjects: Dose-Response Relationship, Drug*; Non-alcoholic Fatty Liver Disease/Non-alcoholic Fatty Liver Disease/Non-alcoholic Fatty Liver Disease/*drug therapy ; Steroids/Steroids/Steroids/*administration & dosage

  • Source: Journal of hepatology [J Hepatol] 2022 Mar; Vol. 76 (3), pp. 506-517. Date of Electronic Publication: 2021 Nov 03.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Once-weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 trial.

  • Authors : Lau DCW; Julia McFarlane Diabetes Research Centre and Libin Cardiovascular Institute of Alberta, University of Calgary Cumming School of Medicine, Calgary, AB, Canada. Electronic address: .; Erichsen L

Subjects: Dose-Response Relationship, Drug*; Islet Amyloid Polypeptide/Islet Amyloid Polypeptide/Islet Amyloid Polypeptide/*therapeutic use ; Obesity/Obesity/Obesity/*drug therapy

  • Source: Lancet (London, England) [Lancet] 2021 Dec 11; Vol. 398 (10317), pp. 2160-2172. Date of Electronic Publication: 2021 Nov 16.Publisher: Elsevier Country of Publication: England NLM ID: 2985213R Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Opportunities and challenges related to saturation of toxicokinetic processes: Implications for risk assessment.

  • Authors : Tan YM; U.S. Environmental Protection Agency, Office of Pesticide Programs, Durham, NC, USA.; Barton HA

Subjects: Dose-Response Relationship, Drug* ; Toxicokinetics*; Toxicity Tests/Toxicity Tests/Toxicity Tests/*methods

  • Source: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Dec; Vol. 127, pp. 105070. Date of Electronic Publication: 2021 Oct 28.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8214983 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Incorporating human exposure information in a weight of evidence approach to inform design of repeated dose animal studies.

  • Authors : Lowe K; U.S. Environmental Protection Agency, Office of Pesticide Programs, Washington, DC, USA.; Dawson J

Subjects: Animal Experimentation* ; Dose-Response Relationship, Drug* ; No-Observed-Adverse-Effect Level*

  • Source: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Dec; Vol. 127, pp. 105073. Date of Electronic Publication: 2021 Oct 29.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8214983 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Exploring the utility of the Threshold of Toxicological Concern (TTC) as a screening approach for complex substances.

  • Authors : Zaleski R; ExxonMobil Biomedical Sciences Inc, 1545 Route 22 East, Annandale, NJ, 08801, USA. Electronic address: .; Embry M

Subjects: Dose-Response Relationship, Drug*; Complex Mixtures/Complex Mixtures/Complex Mixtures/*analysis ; Complex Mixtures/Complex Mixtures/Complex Mixtures/*toxicity

  • Source: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Dec; Vol. 127, pp. 105051. Date of Electronic Publication: 2021 Oct 03.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8214983 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Personalized Variable vs Fixed-Dose Systemic Corticosteroid Therapy in Hospitalized Patients With Acute Exacerbations of COPD: A Prospective, Multicenter, Randomized, Open-Label Clinical Trial.

  • Authors : Li L; Department of Respiratory Medicine, Daping Hospital, Third Military Medical University (Army Medical University), Chongqing, China.; Zhao N

Subjects: Dose-Response Relationship, Drug* ; Glucocorticoids*/Glucocorticoids*/Glucocorticoids*/administration & dosage ; Glucocorticoids*/Glucocorticoids*/Glucocorticoids*/adverse effects

  • Source: Chest [Chest] 2021 Nov; Vol. 160 (5), pp. 1660-1669. Date of Electronic Publication: 2021 May 21.Publisher: Elsevier Country of Publication: United States NLM ID: 0231335 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Synthesis, molecular docking, and evaluation of antibacterial activity of 1,2,4-triazole-norfloxacin hybrids.

  • Authors : Yang P; Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, State Key Laboratory of Applied Microbiology Southern China, Institute of Microbiology, Guangdong Academy of Sciences, Guangdong Detection Center of Microbiology, Guangzhou 510070, China; Guangdong Demay New Materials Technology Co. Ltd., Guangzhou 510070, China.

Subjects: Dose-Response Relationship, Drug* ; Molecular Docking Simulation*; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*pharmacology

  • Source: Bioorganic chemistry [Bioorg Chem] 2021 Oct; Vol. 115, pp. 105270. Date of Electronic Publication: 2021 Aug 17.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Filgotinib as induction and maintenance therapy for ulcerative colitis (SELECTION): a phase 2b/3 double-blind, randomised, placebo-controlled trial.

  • Authors : Feagan BG; Alimentiv, London, ON, Canada; Division of Gastroenterology, London Health Sciences Centre, Western University, London, ON, Canada. Electronic address: .

Subjects: Dose-Response Relationship, Drug* ; Remission Induction*; Colitis, Ulcerative/Colitis, Ulcerative/Colitis, Ulcerative/*drug therapy

  • Source: Lancet (London, England) [Lancet] 2021 Jun 19; Vol. 397 (10292), pp. 2372-2384. Date of Electronic Publication: 2021 Jun 03.Publisher: Elsevier Country of Publication: England NLM ID: 2985213R Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Once-daily upadacitinib versus placebo in adolescents and adults with moderate-to-severe atopic dermatitis (Measure Up 1 and Measure Up 2): results from two replicate double-blind, randomised controlled phase 3 trials.

  • Authors : Guttman-Yassky E; Department of Dermatology and Laboratory for Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Teixeira HD

Subjects: Dose-Response Relationship, Drug* ; Severity of Illness Index*; Dermatitis, Atopic/Dermatitis, Atopic/Dermatitis, Atopic/*drug therapy

  • Source: Lancet (London, England) [Lancet] 2021 Jun 05; Vol. 397 (10290), pp. 2151-2168. Date of Electronic Publication: 2021 May 21.Publisher: Elsevier Country of Publication: England NLM ID: 2985213R Publication Model: Print-Electronic Cited Medium:

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  • 1-10 of  46,981 results for ""Dose-Response Relationship, Drug""