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Academic Journal

Phenothiazine normalizes the NADH/NAD + ratio, maintains mitochondrial integrity and protects the nigrostriatal dopamine system in a chronic rotenone model of Parkinson's disease.

  • Authors : Tapias V; Department of Neurology, USA; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15260, USA. Electronic address: .

Subjects: Dopamine/Dopamine/Dopamine/*metabolism ; Dopaminergic Neurons/Dopaminergic Neurons/Dopaminergic Neurons/*drug effects ; Dopaminergic Neurons/Dopaminergic Neurons/Dopaminergic Neurons/*metabolism

  • Source: Redox biology [Redox Biol] 2019 Jun; Vol. 24, pp. 101164. Date of Electronic Publication: 2019 Mar 21.Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Overexpression of VMAT-2 and DT-diaphorase protects substantia nigra-derived cells against aminochrome neurotoxicity.

  • Authors : Muñoz P; Molecular and Clinical Pharmacology, Faculty of Medicine, University of Chile, Santiago 8380453, Chile.; Paris I

Subjects: Dopamine/Dopamine/Dopamine/*metabolism ; Indolequinones/Indolequinones/Indolequinones/*toxicity ; NAD(P)H Dehydrogenase (Quinone)/NAD(P)H Dehydrogenase (Quinone)/NAD(P)H Dehydrogenase (Quinone)/*metabolism

  • Source: Biochimica et biophysica acta [Biochim Biophys Acta] 2012 Jul; Vol. 1822 (7), pp. 1125-36. Date of Electronic Publication: 2012 Mar 27.Publisher: Elsevier Pub. Co Country of Publication: Netherlands NLM ID: 0217513 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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Academic Journal

Hypokinesia and reduced dopamine levels in zebrafish lacking β- and γ1-synucleins.

  • Authors : Milanese C; Pittsburgh Institute for Neurodegenerative Diseases and Department of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.; Sager JJ

Subjects: Dopamine/Dopamine/Dopamine/*metabolism ; Dopaminergic Neurons/Dopaminergic Neurons/Dopaminergic Neurons/*metabolism ; Motor Activity/Motor Activity/Motor Activity/*physiology

  • Source: The Journal of biological chemistry [J Biol Chem] 2012 Jan 27; Vol. 287 (5), pp. 2971-83. Date of Electronic Publication: 2011 Nov 29.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Regulation of complex I by Engrailed is complex too.

  • Authors : Sanders LH; Pittsburgh Institute for Neurodegenerative Diseases and Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Greenamyre JT

Subjects: Dopamine/Dopamine/Dopamine/*metabolism ; Homeodomain Proteins/Homeodomain Proteins/Homeodomain Proteins/*metabolism ; Mesencephalon/Mesencephalon/Mesencephalon/*cytology

  • Source: Nature neuroscience [Nat Neurosci] 2011 Sep 27; Vol. 14 (10), pp. 1221-2. Date of Electronic Publication: 2011 Sep 27.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Single-cell redox imaging demonstrates a distinctive response of dopaminergic neurons to oxidative insults.

  • Authors : Horowitz MP; Medical Scientist Training Program, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Milanese C

Subjects: Single-Cell Analysis*; Brain Mapping/Brain Mapping/Brain Mapping/*methods ; Dopamine/Dopamine/Dopamine/*physiology

  • Source: Antioxidants & redox signaling [Antioxid Redox Signal] 2011 Aug 15; Vol. 15 (4), pp. 855-71. Date of Electronic Publication: 2011 Jun 06.Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 100888899 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Peroxiredoxin-2 protects against 6-hydroxydopamine-induced dopaminergic neurodegeneration via attenuation of the apoptosis signal-regulating kinase (ASK1) signaling cascade.

  • Authors : Hu X; Pittsburgh Institute of Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.; Weng Z

Subjects: Dopamine/Dopamine/Dopamine/*metabolism ; MAP Kinase Kinase Kinase 5/MAP Kinase Kinase Kinase 5/MAP Kinase Kinase Kinase 5/*drug effects ; Neurodegenerative Diseases/Neurodegenerative Diseases/Neurodegenerative Diseases/*prevention & control

  • Source: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2011 Jan 05; Vol. 31 (1), pp. 247-61.Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Neuron-selective changes in RNA transcripts related to energy metabolism in toxic models of parkinsonism in rodents.

  • Authors : Greene JG; Departments of Neurology and Pharmacology, and the Center for Neurodegenerative Disease, Emory University School of Medicine, Atlanta, GA, USA. ; Dingledine R

Subjects: Dopamine/Dopamine/Dopamine/*metabolism ; Neurons/Neurons/Neurons/*metabolism ; Parkinsonian Disorders/Parkinsonian Disorders/Parkinsonian Disorders/*metabolism

  • Source: Neurobiology of disease [Neurobiol Dis] 2010 Jun; Vol. 38 (3), pp. 476-81. Date of Electronic Publication: 2010 Mar 20.Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

NeuN is not a reliable marker of dopamine neurons in rat substantia nigra.

  • Authors : Cannon JR; Department of Neurology, Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15260, United States.; Greenamyre JT

Subjects: Dopamine/Dopamine/Dopamine/*metabolism ; Neurons/Neurons/Neurons/*metabolism ; Substantia Nigra/Substantia Nigra/Substantia Nigra/*metabolism

  • Source: Neuroscience letters [Neurosci Lett] 2009 Oct 16; Vol. 464 (1), pp. 14-7. Date of Electronic Publication: 2009 Aug 12.Publisher: Elsevier Scientific Publishers Ireland Country of Publication: Ireland NLM ID: 7600130 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Obligatory role for complex I inhibition in the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

  • Authors : Richardson JR; Department of Environmental and Occupational Medicine, University of Medicine and Dentistry, New Jersey/Robert Wood Johnson Medical School and Environmental and Occupational Health Sciences Institute, Piscataway, New Jersey 08854, USA.; Caudle WM

Subjects: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine/*adverse effects ; Dopamine/Dopamine/Dopamine/*metabolism ; Electron Transport Complex I/Electron Transport Complex I/Electron Transport Complex I/*antagonists & inhibitors

  • Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2007 Jan; Vol. 95 (1), pp. 196-204. Date of Electronic Publication: 2006 Oct 12.Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print-Electronic Cited Medium: Print

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Academic Journal

Rotenone induces oxidative stress and dopaminergic neuron damage in organotypic substantia nigra cultures.

  • Authors : Testa CM; Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, USA. ; Sherer TB

Subjects: Dopamine/Dopamine/Dopamine/*metabolism ; Nerve Degeneration/Nerve Degeneration/Nerve Degeneration/*chemically induced ; Neurons/Neurons/Neurons/*drug effects

  • Source: Brain research. Molecular brain research [Brain Res Mol Brain Res] 2005 Mar 24; Vol. 134 (1), pp. 109-18. Date of Electronic Publication: 2005 Jan 06.Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8908640 Publication Model: Print-Electronic Cited Medium: Print

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  • 1-10 of  21 results for ""Greenamyre JT""