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Academic Journal

Decreased expression of GLT-1 in the R6/2 model of Huntington's disease does not worsen disease progression.

Subjects: GLUTAMATE transporters; HUNTINGTON'S chorea diagnosis; DRUG administration

  • Source: European Journal of Neuroscience. Aug2013, Vol. 38 Issue 3, p2477-2490. 14p. 1 Black and White Photograph, 7 Graphs.

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Academic Journal

Getting a handle on Huntington's disease: silencing neurodegeneration.

Subjects: *HUNTINGTON'S chorea treatment; *NEURODEGENERATION; *GENE silencing

  • Source: Nature Medicine. Mar2009, Vol. 15 Issue 3, p252-253. 2p.

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Academic Journal

Amelioration of Huntington's disease phenotypes by Beta-Lapachone is associated with increases in Sirt1 expression, CREB phosphorylation and PGC-1α deacetylation.

Subjects: HUNTINGTON'S chorea diagnosis; BETA-lapachone; PHENOTYPES

  • Source: PLoS ONE; 5/9/2018, Vol. 13 Issue 5, p1-15, 15p

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Academic Journal

Pridopidine Reverses Phencyclidine-Induced Memory Impairment.

Subjects: HUNTINGTON'S chorea treatment; PHENCYCLIDINE; CLINICAL trials

  • Source: Frontiers in Pharmacology; 4/10/2018, p1-N.PAG, 4p

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Academic Journal

MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice.

Subjects: MICRORNA; HUNTINGTON'S chorea diagnosis; RNA sequencing

  • Source: PLoS ONE; 1/11/2018, Vol. 13 Issue 1, p1-20, 20p

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Academic Journal

Possible use of a H3R antagonist for the management of nonmotor symptoms in the Q175 mouse model of Huntington's disease.

Subjects: ANTIHISTAMINES; HUNTINGTON'S chorea treatment; SYMPTOMS

  • Source: Pharmacology Research & Perspectives; Oct2017, Vol. 5 Issue 5, pn/a-N.PAG, 17p

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Academic Journal

Adult neural progenitor cells from Huntington's disease mouse brain exhibit increased proliferation and migration due to enhanced calcium and ROS signals.

Subjects: PROGENITOR cells; HUNTINGTON'S chorea treatment; CELLULAR signal transduction

  • Source: Cell Proliferation. Oct2015, Vol. 48 Issue 5, p517-531. 15p.

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Academic Journal

In vivo proof-of-concept of removal of the huntingtin caspase cleavage motif-encoding exon 12 approach in the YAC128 mouse model of Huntington’s disease.

Subjects: *HUNTINGTON'S chorea treatment; *HUNTINGTIN protein; *LABORATORY mice

  • Source: Biomedicine & Pharmacotherapy. Dec2016, Vol. 84, p93-96. 4p.

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Academic Journal

Glial cells -- friend and foe in Huntington disease?

Subjects: *NEUROGLIA; *HUNTINGTON'S chorea treatment; *PROGENITOR cells

  • Source: Nature Reviews Neurology. Aug2016, Vol. 12 Issue 8, p430-431. 2p.

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Academic Journal

The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington’s Disease Mice.

Subjects: HUNTINGTON'S chorea treatment; HISTONE deacetylase inhibitors; EPIGENETICS

  • Source: PLoS ONE; 3/31/2016, Vol. 11 Issue 3, p1-14, 14p

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  • 1-10 of  123 results for ""HUNTINGTON'S chorea""