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Academic Journal

Denosumab Attenuates Glucolipotoxicity-Induced β-Cell Dysfunction and Apoptosis by Attenuating RANK/RANKL Signals.

  • Authors : Lin SC; Institute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.; Department of Orthopaedics, Chung Shan Medical University Hospital, Taichung 402, Taiwan.

Subjects: Apoptosis* ; Denosumab*/Denosumab*/Denosumab*/pharmacology ; Insulin-Secreting Cells*/Insulin-Secreting Cells*/Insulin-Secreting Cells*/drug effects

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 17; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Abelmoschus esculentus subfractions attenuate beta amyloid-induced neuron apoptosis by regulating DPP-4 with improving insulin resistance signals.

  • Authors : Huang CN; Department of Internal Medicine, Chung-Shan Medical University Hospital, Taichung, Taiwan.; Institute of Medicine, Chung-Shan Medical University, Taichung, Taiwan.

Subjects: Insulin Resistance*; Abelmoschus/Abelmoschus/Abelmoschus/*chemistry ; Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*metabolism

  • Source: PloS one [PLoS One] 2019 Jun 25; Vol. 14 (6), pp. e0217400. Date of Electronic Publication: 2019 Jun 25 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Liraglutide protects against glucolipotoxicity-induced RIN-m5F β-cell apoptosis through restoration of PDX1 expression.

  • Authors : Kornelius E; Division of Endocrinology and Metabolism, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.; Li HH

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Glucose/Glucose/Glucose/*pharmacology ; Homeodomain Proteins/Homeodomain Proteins/Homeodomain Proteins/*metabolism

  • Source: Journal of cellular and molecular medicine [J Cell Mol Med] 2019 Jan; Vol. 23 (1), pp. 619-629. Date of Electronic Publication: 2018 Oct 24.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Active subfractions of Abelmoschus esculentus substantially prevent free fatty acid-induced β cell apoptosis via inhibiting dipeptidyl peptidase-4.

  • Authors : Huang CN; Department of Internal Medicine, Chung-Shan Medical University Hospital, Taichung, Taiwan.; Institute of Medicine, Chung-Shan Medical University, Taichung, Taiwan.

Subjects: Abelmoschus/Abelmoschus/Abelmoschus/*chemistry ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Dipeptidyl-Peptidase IV Inhibitors/Dipeptidyl-Peptidase IV Inhibitors/Dipeptidyl-Peptidase IV Inhibitors/*pharmacology

  • Source: PloS one [PLoS One] 2017 Jul 17; Vol. 12 (7), pp. e0180285. Date of Electronic Publication: 2017 Jul 17 (Print Publication: 2017).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Impact of polyphenolic components from mulberry on apoptosis of vascular smooth muscle cells.

  • Authors : Chan KC; Department of Internal Medicine, Chung Shan Medical University Hospital, No. 110, Sec. 1, Jianguo N. Road, Taichung 402, Taiwan.; School of Medicine, Institute of Medicine, Chung Shan Medical University, No. 110, Sec. 1, Jianguo N. Road, Taichung 402, Taiwan.

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Morus/Morus/Morus/*chemistry ; Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/Muscle, Smooth, Vascular/*cytology

  • Source: Journal of the science of food and agriculture [J Sci Food Agric] 2016 Jan 30; Vol. 96 (2), pp. 381-91. Date of Electronic Publication: 2015 Feb 19.Publisher: John Wiley & Sons Country of Publication: England NLM ID: 0376334 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mulberry water extracts inhibit rabbit atherosclerosis through stimulation of vascular smooth muscle cell apoptosis via activating p53 and regulating both intrinsic and extrinsic pathways.

  • Authors : Chan KC; Department of Internal Medicine, Chung-Shan Medical University Hospital , No. 110, Sec. 1, Jianguo N. Road, Taichung 402, Taiwan.; Ho HH

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Atherosclerosis/Atherosclerosis/Atherosclerosis/*drug therapy ; Atherosclerosis/Atherosclerosis/Atherosclerosis/*physiopathology

  • Source: Journal of agricultural and food chemistry [J Agric Food Chem] 2014 Jun 04; Vol. 62 (22), pp. 5092-101. Date of Electronic Publication: 2014 May 23.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Molecular action mechanism against apoptosis by aqueous extract from guava budding leaves elucidated with human umbilical vein endothelial cell (HUVEC) model.

  • Authors : Hsieh CL; Department of Food and Nutrition, Research Institute of Biotechnology, Hungkuang University, 34 Chung-Chie Road, Shalu County, Taichung Hsien, Taiwan. ; Huang CN

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Endothelial Cells/Endothelial Cells/Endothelial Cells/*drug effects ; Plant Extracts/Plant Extracts/Plant Extracts/*pharmacology

  • Source: Journal of agricultural and food chemistry [J Agric Food Chem] 2007 Oct 17; Vol. 55 (21), pp. 8523-33. Date of Electronic Publication: 2007 Sep 26.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Print

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Academic Journal

Penta-acetyl geniposide-induced apoptosis involving transcription of NGF/p75 via MAPK-mediated AP-1 activation in C6 glioma cells.

  • Authors : Peng CH; Department of Nursing, Hungkuang University, Sha Lu, Taichung, Taiwan.; Huang CN

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Glucosides/Glucosides/Glucosides/*toxicity ; Iridoids/Iridoids/Iridoids/*toxicity

  • Source: Toxicology [Toxicology] 2007 Sep 05; Vol. 238 (2-3), pp. 130-9. Date of Electronic Publication: 2007 Jun 12.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0361055 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0300-483X

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Academic Journal

Penta-acetyl geniposide induce apoptosis in C6 glioma cells by modulating the activation of neutral sphingomyelinase-induced p75 nerve growth factor receptor and protein kinase Cdelta pathway.

  • Authors : Peng CH; Department of Nursing, Hungkuang University, Sha Lu, Taichung, Taiwan.; Huang CN

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Glioma/Glioma/Glioma/*pathology ; Iridoids/Iridoids/Iridoids/*pharmacology

  • Source: Molecular pharmacology [Mol Pharmacol] 2006 Sep; Vol. 70 (3), pp. 997-1004. Date of Electronic Publication: 2006 Jun 08.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0035623 Publication Model:

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Academic Journal

Apoptosis induced by penta-acetyl geniposide in C6 glioma cells is associated with JNK activation and Fas ligand induction.

  • Authors : Peng CH; Institute of Biochemistry, Chung Shan Medical University, Chien Kuo N. Road, Taichung 402, Taiwan.; Tseng TH

Subjects: Cell Line, Tumor*; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Glucosides/Glucosides/Glucosides/*pharmacology

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2005 Jan 15; Vol. 202 (2), pp. 172-9.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print Cited Medium: Print ISSN: 0041-008X

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