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Predicting transcriptional outcomes of novel multigene perturbations with GEARS

• Authors : Roohani, Yusuf; Huang, Kexin; Leskovec, Jure

• Source: Nature Biotechnology; 20240101, Issue: Preprints p1-9, 9p

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CRISPR editing in the lung with novel lipids.

• Authors : Elia U; Laboratory of Precision NanoMedicine, Shmunis School for Biomedicine and Cancer Research, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.; Center for Nanoscience and Nanotechnology, Tel Aviv University, Tel Aviv, Israel.

• Source: Nature biotechnology [Nat Biotechnol] 2023 Oct; Vol. 41 (10), pp. 1387-1388.Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print Cited Medium: Internet ISSN:

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Predicting transcriptional outcomes of novel multigene perturbations with GEARS.

• Authors : Roohani Y; Department of Biomedical Data Science, Stanford University, Stanford, CA, USA.; Huang K

• Source: Nature biotechnology [Nat Biotechnol] 2023 Aug 17. Date of Electronic Publication: 2023 Aug 17.Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet

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Novel recombinases for large DNA insertions.

• Authors : Lampe GD; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.; Sternberg SH

Subjects: Recombinases*/Recombinases*/Recombinases*/genetics ; DNA*/DNA*/DNA*/genetics; Genetic Engineering

• Source: Nature biotechnology [Nat Biotechnol] 2023 Apr; Vol. 41 (4), pp. 471-472.Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print Cited Medium: Internet ISSN:

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A novel computational architecture for large-scale genomics.

• Authors : Becker, Matthias; Schultze, Hartmut; Bresniker, Kirk

• Source: Nature Biotechnology. 2020, Vol. 38, Issue 11, pages. 3

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Drugging the gut microbiome: using conventional drug discovery and novel synthetic biology approaches, some investigators and companies are mining our resident microbes and their metabolites for targets in small-molecule drug programs.

• Authors : Garber, Ken; Arbor, Ann

• Source: Nature Biotechnology. 2015, Vol. 33, Issue 3, pages. 4

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Corporate venture capital and cambridge: a novel route to entrepreneurship at the University of Cambridge.

• Authors : McCammon, Margaret G.; Pio, Edwina; Barakat, Shima

• Source: Nature Biotechnology. 2014, Vol. 32, Issue 10, pages. 4

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DREAMing of a patent-free human genome for clinical sequencing: can methylation be the key to challenging the interpretation of existing gene patent claims? And can a novel PCR method be used to enable the sequencing of hundreds of genes?

• Authors : McKernan, Kevin J.; Spangler, Jessica; Helbert, Yvonne

• Source: Nature Biotechnology. 2013, Vol. 31, Issue 10, pages. 5

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More than insulin: for a century, insulin has been the only drug available to type 1 diabetics. Now a raft of novel drugs are coming through the pipeline.

• Authors : Eisenstein, Michael

• Source: Nature Biotechnology. 2011, Vol. 29, Issue 9, pages. 4

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Peering inside Alzheimer's brains: last year's failure of Eli Lilly's drug semagacestat in late-stage clinical trials was the latest in a long line of setbacks for novel Alzheimer's therapies. But advances in imaging and biomarker identification are providing added impetus to ongoing drug development.

• Authors : Sinha, Gunjan

• Source: Nature Biotechnology. 2011, Vol. 29, Issue 5, pages. 4

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