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Academic Journal

Novel strategies based on natural products and synthetic derivatives to overcome resistance in Mycobacterium tuberculosis.

  • Authors : Niculescu AG; Research Institute of the University of Bucharest, University of Bucharest, 90 Panduri Road, Bucharest, Romania; Department of Science and Engineering of Oxide Materials and Nanomaterials, National University of Science and Technology Politehnica Bucharest, 011061, Bucharest, Romania. Electronic address: .

Subjects: Mycobacterium tuberculosis* ; Biological Products*/Biological Products*/Biological Products*/pharmacology ; Biological Products*/Biological Products*/Biological Products*/therapeutic use

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 Apr 05; Vol. 269, pp. 116268. Date of Electronic Publication: 2024 Feb 23.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Bactericidal and sterilizing activity of novel regimens combining bedaquiline or TBAJ-587 with GSK2556286 and TBA-7371 in a mouse model of tuberculosis.

  • Authors : Li S-Y; Center for Tuberculosis Research, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Tyagi S

Subjects: Mycobacterium tuberculosis* ; Tuberculosis*/Tuberculosis*/Tuberculosis*/drug therapy ; Nitroimidazoles*/Nitroimidazoles*/Nitroimidazoles*/pharmacology

  • Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2024 Apr 03; Vol. 68 (4), pp. e0156223. Date of Electronic Publication: 2024 Feb 20.Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

In silico drug design strategies for discovering novel tuberculosis therapeutics.

  • Authors : Canales CSC; School of Pharmaceutical Science, São Paulo State University (UNESP), Araraquara, Brazil.; School of Pharmacy, biochemistry and biotechnology, Santa Maria Catholic University, Arequipa, Perú.

Subjects: Tuberculosis*/Tuberculosis*/Tuberculosis*/drug therapy ; Tuberculosis*/Tuberculosis*/Tuberculosis*/microbiology ; Mycobacterium tuberculosis*

  • Source: Expert opinion on drug discovery [Expert Opin Drug Discov] 2024 Apr; Vol. 19 (4), pp. 471-491. Date of Electronic Publication: 2024 Feb 19.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101295755 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Computational screening of natural MtbDXR inhibitors for novel anti-tuberculosis compound discovery.

  • Authors : Islam S; Biotechnology and Genetic Engineering Discipline, Life Science School, Khulna University, Khulna, Bangladesh.; Salekeen R

Subjects: Tuberculosis*/Tuberculosis*/Tuberculosis*/drug therapy ; Mycobacterium tuberculosis*; Humans

  • Source: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2024 Apr; Vol. 42 (7), pp. 3593-3603. Date of Electronic Publication: 2023 Jun 05.Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Molecular modeling and biological investigation of novel s-triazine linked benzothiazole and coumarin hybrids as antimicrobial and antimycobacterial agents.

  • Authors : Zala AR; Department of Chemistry, Sardar Vallabhbhai National Institute of Technology, Surat, Gujarat, India.; Kumar D

Subjects: Anti-Infective Agents*/Anti-Infective Agents*/Anti-Infective Agents*/pharmacology ; Mycobacterium tuberculosis*; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/pharmacology

  • Source: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2024 Apr; Vol. 42 (7), pp. 3814-3825. Date of Electronic Publication: 2023 May 22.Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Synthesis of Novel Triazine-Based Chalcones and 8,9-dihydro-7 H -pyrimido[4,5- b ][1,4]diazepines as Potential Leads in the Search of Anticancer, Antibacterial and Antifungal Agents.

  • Authors : Moreno LM; Grupo de Investigación de Compuestos Heterocíclicos, Departamento de Química, Universidad del Valle, Cali 760042, Colombia.; Quiroga J

Subjects: Chalcones*/Chalcones*/Chalcones*/pharmacology ; Mycobacterium tuberculosis* ; Isocyanates*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 23; Vol. 25 (7). Date of Electronic Publication: 2024 Mar 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Discovery of 2,9-diaryl-6-carbamoylpurines as a novel class of antitubercular agents.

  • Authors : Correia C; CQUM - Centre of Chemistry, Department of Chemistry, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal.; Leite AC

Subjects: Mycobacterium tuberculosis* ; Tuberculosis*/Tuberculosis*/Tuberculosis*/drug therapy ; Tuberculosis*/Tuberculosis*/Tuberculosis*/microbiology

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 Mar 15; Vol. 268, pp. 116297. Date of Electronic Publication: 2024 Mar 02.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Identification of Novel Antimicrobial Compounds Targeting Mycobacterium tuberculosis S -Adenosyl-L-Homocysteine Hydrolase Using Dual Hierarchical In Silico Structure-Based Drug Screening.

  • Authors : Ito H; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, Iizuka 820-8502, Japan.; Monobe K

Subjects: Mycobacterium tuberculosis* ; Tuberculosis*/Tuberculosis*/Tuberculosis*/microbiology; Humans

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Mar 14; Vol. 29 (6). Date of Electronic Publication: 2024 Mar 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

The diagnosis of central nervous system infections in resource-limited settings and the use of novel and molecular diagnostic platforms to improve diagnosis.

  • Authors : Milburn J; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana.; Department of Clinical Research, Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.

Subjects: Mycobacterium tuberculosis*/Mycobacterium tuberculosis*/Mycobacterium tuberculosis*/genetics; Humans ; Pathology, Molecular

  • Source: Expert review of molecular diagnostics [Expert Rev Mol Diagn] 2024 Mar; Vol. 24 (3), pp. 219-230. Date of Electronic Publication: 2024 Feb 19.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101120777 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A novel synergistic enzyme-antibiotic therapy with immobilization of mycobacteriophage Lysin B enzyme onto Rif@UiO-66 nanocomposite for enhanced inhaled anti-TB therapy; Nanoenzybiotics approach.

  • Authors : Eldin ZE; Materials Science and Nanotechnology Department, Faculty of Postgraduate Studies for Advanced Sciences, Beni-Suef University, 62511 Beni-Suef, Egypt. Electronic address: .; Dishisha T

Subjects: Mycobacteriophages* ; Tuberculosis*/Tuberculosis*/Tuberculosis*/drug therapy ; Mycobacterium tuberculosis*

  • Source: International journal of biological macromolecules [Int J Biol Macromol] 2024 Mar; Vol. 262 (Pt 1), pp. 129675. Date of Electronic Publication: 2024 Jan 26.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  3,247 results for ""Novel""