Search Results

Filter
  • 1-10 of  1,960 results for ""United States""
Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request
Academic Journal

Quick and Accurate Estimates of Mutation Effects on Transition-State Stabilization of Enzymes from Molecular Simulations with Restrained Transition States.

  • Authors : Burgin T; Department of Chemical Engineering, University of Washington, Seattle, Washington 98195, United States.; Pfaendtner J

Subjects: Mutation*

  • Source: The journal of physical chemistry. B [J Phys Chem B] 2022 Dec 08; Vol. 126 (48), pp. 9964-9970. Date of Electronic Publication: 2022 Nov 22.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101157530

Record details

×
Academic Journal

Molecular Dynamics-Derived Descriptor Informs the Impact of Mutation on the Catalytic Turnover Number in Lactonase Across Substrates.

  • Authors : Jiang Y; Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.; Yan B

Subjects: Catalytic Domain*/Catalytic Domain*/Catalytic Domain*/genetics ; Molecular Dynamics Simulation* ; Mutation*/Mutation*/Mutation*/genetics

  • Source: The journal of physical chemistry. B [J Phys Chem B] 2022 Apr 07; Vol. 126 (13), pp. 2486-2495. Date of Electronic Publication: 2022 Mar 24.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101157530

Record details

×
Academic Journal

SNAP25 mutation disrupts metabolic homeostasis, steroid hormone production and central neurobehavior.

  • Authors : Hao X; Division of Endocrinology, Gerontology and Metabolism, Stanford University School of Medicine, Stanford, CA, United States; Geriatric Research, Education, and Clinical Center, Veterans Administration Palo Alto Health Care System, Palo Alto, CA, United States

Subjects: Behavior, Animal* ; Homeostasis* ; Insulin Resistance*

  • Source: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2022 Feb 01; Vol. 1868 (2), pp. 166304. Date of Electronic Publication: 2021 Nov 24.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

×
Academic Journal

Clonal hematopoiesis: Molecular and clinical implications.

  • Authors : Kusne Y; Division of Hematology Oncology, Mayo Clinic, Arizona, United States.; Xie Z

Subjects: Mutation*; Aging/Aging/Aging/*genetics ; Clonal Hematopoiesis/Clonal Hematopoiesis/Clonal Hematopoiesis/*genetics

  • Source: Leukemia research [Leuk Res] 2022 Feb; Vol. 113, pp. 106787. Date of Electronic Publication: 2022 Jan 10.Publisher: Pergamon Press Country of Publication: England NLM ID: 7706787 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

×
Academic Journal

Accurate Prediction of Protein Thermodynamic Stability Changes upon Residue Mutation using Free Energy Perturbation.

  • Authors : Scarabelli G; Schrodinger Inc, 1540 Broadway 24th Floor, New York, NY 10036, United States.; Oloo EO

Subjects: Entropy* ; Mutation* ; Thermodynamics*

  • Source: Journal of molecular biology [J Mol Biol] 2022 Jan 30; Vol. 434 (2), pp. 167375. Date of Electronic Publication: 2021 Nov 23.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

×
Academic Journal

Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose.

  • Authors : Zhang L; Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States.; Moccia M

Subjects: Mutation*; Adenocarcinoma of Lung/Adenocarcinoma of Lung/Adenocarcinoma of Lung/*drug therapy ; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*drug therapy

  • Source: Journal of medicinal chemistry [J Med Chem] 2022 Jan 27; Vol. 65 (2), pp. 1536-1551.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531

Record details

×
Academic Journal

Design of a "Two-in-One" Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites.

  • Authors : Wittlinger F; Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.; Heppner DE

Subjects: Drug Design* ; Mutation*; Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/*drug therapy

  • Source: Journal of medicinal chemistry [J Med Chem] 2022 Jan 27; Vol. 65 (2), pp. 1370-1383. Date of Electronic Publication: 2021 Oct 20.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531

Record details

×
Academic Journal

Linking protein structural and functional change to mutation using amino acid networks.

Subjects: Amino Acid Sequence* ; Amino Acids*/Amino Acids*/Amino Acids*/chemistry ; Amino Acids*/Amino Acids*/Amino Acids*/genetics

  • Source: PloS one [PLoS One] 2022 Jan 21; Vol. 17 (1), pp. e0261829. Date of Electronic Publication: 2022 Jan 21 (Print Publication: 2022).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081

Record details

×
Academic Journal

Massively parallel reporter assays discover de novo exonic splicing mutants in paralogs of Autism genes.

  • Authors : Rhine CL; Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, United States of America.; Autism & Developmental Medicine Institute, and Genomic Medicine Institute, Geisinger, Danville, Pennsylvania, United States of America.

Subjects: Mutation* ; RNA Splicing*; Autism Spectrum Disorder/Autism Spectrum Disorder/Autism Spectrum Disorder/*genetics

  • Source: PLoS genetics [PLoS Genet] 2022 Jan 20; Vol. 18 (1), pp. e1009884. Date of Electronic Publication: 2022 Jan 20 (Print Publication: 2022).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074

Record details

×
Academic Journal

Limits to detecting epistasis in the fitness landscape of HIV.

  • Authors : Biswas A; Department of Physics, Temple University, Philadelphia, PA, United States of America.; Center for Biophysics and Computational Biology, Temple University, Philadelphia, PA, United States of America.

Subjects: Epistasis, Genetic* ; Genetic Fitness* ; Mutation*

  • Source: PloS one [PLoS One] 2022 Jan 18; Vol. 17 (1), pp. e0262314. Date of Electronic Publication: 2022 Jan 18 (Print Publication: 2022).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081

Record details

×
  • 1-10 of  1,960 results for ""United States""