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Academic Journal

MPO/HOCl Facilitates Apoptosis and Ferroptosis in the SOD1 G93A Motor Neuron of Amyotrophic Lateral Sclerosis.

  • Authors : Peng J; Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.; Pan J

Subjects: Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/*therapy ; Apoptosis/Apoptosis/Apoptosis/*physiology ; Ferroptosis/Ferroptosis/Ferroptosis/*physiology

  • Source: Oxidative medicine and cellular longevity [Oxid Med Cell Longev] 2022 Feb 07; Vol. 2022, pp. 8217663. Date of Electronic Publication: 2022 Feb 07 (Print Publication: 2022).Publisher: Hindawi Pub. Corp Country of Publication: United States NLM ID: 101479826 Publication Model: eCollection Cited Medium: Internet ISSN:

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Academic Journal

Downregulation of miR-335-5P in Amyotrophic Lateral Sclerosis Can Contribute to Neuronal Mitochondrial Dysfunction and Apoptosis.

  • Authors : De Luna N; Neuromuscular Diseases Laboratory - Biomedical Research Institute SantPau, Universitat Autónoma de Barcelona, Barcelona, Spain. .; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Valencia, Spain. .

Subjects: Apoptosis* ; Gene Expression Regulation, Neoplastic*; Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/*pathology

  • Source: Scientific reports [Sci Rep] 2020 Mar 09; Vol. 10 (1), pp. 4308. Date of Electronic Publication: 2020 Mar 09.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

A glaucoma- and ALS-associated mutant of OPTN induces neuronal cell death dependent on Tbk1 activity, autophagy and ER stress.

  • Authors : Medchalmi S; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.; Tare P

Subjects: Apoptosis* ; Mutation*; Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/*genetics

  • Source: The FEBS journal [FEBS J] 2021 Aug; Vol. 288 (15), pp. 4576-4595. Date of Electronic Publication: 2021 Feb 19.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication

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Academic Journal

Systemic administration of scAAV9-IGF1 extends survival in SOD1 G93A ALS mice via inhibiting p38 MAPK and the JNK-mediated apoptosis pathway.

  • Authors : Wang W; Department of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, People's Republic of China; Department of Neurology, Affiliated Xing Tai People Hospital of Hebei Medical University, Xingtai, Hebei, 054000, People's Republic of China.

Subjects: Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/*therapy ; Apoptosis/Apoptosis/Apoptosis/*physiology ; Insulin-Like Growth Factor I/Insulin-Like Growth Factor I/Insulin-Like Growth Factor I/*metabolism

  • Source: Brain research bulletin [Brain Res Bull] 2018 May; Vol. 139, pp. 203-210. Date of Electronic Publication: 2018 Feb 27.Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605818 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

MicroRNAs as regulators of cell death mechanisms in amyotrophic lateral sclerosis.

  • Authors : Gagliardi D; Dino Ferrari Centre, Neuroscience Section, Department of Pathophysiology and Transplantation (DEPT), Neurology Unit, IRCCS Foundation Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.; Comi GP

Subjects: Apoptosis* ; Necrosis*; Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/*pathology

  • Source: Journal of cellular and molecular medicine [J Cell Mol Med] 2019 Mar; Vol. 23 (3), pp. 1647-1656. Date of Electronic Publication: 2019 Jan 04.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Raloxifene, a promising estrogen replacement, limits TDP-25 cell death by enhancing autophagy and suppressing apoptosis.

  • Authors : Zhou F; Department of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, People's Republic of China.; Dong H

Subjects: Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/*drug therapy ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Autophagy/Autophagy/Autophagy/*drug effects

  • Source: Brain research bulletin [Brain Res Bull] 2018 Jun; Vol. 140, pp. 281-290. Date of Electronic Publication: 2018 May 25.Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605818 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Deregulated miR-29b-3p Correlates with Tissue-Specific Activation of Intrinsic Apoptosis in An Animal Model of Amyotrophic Lateral Sclerosis.

  • Authors : Klatt CL; Ruhr University Bochum, Medical Faculty, Institute of Anatomy, Department of Cytology, 44801 Bochum, Germany. .; Theis V

Subjects: Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/*metabolism ; Apoptosis/Apoptosis/Apoptosis/*physiology ; Cerebellum/Cerebellum/Cerebellum/*metabolism

  • Source: Cells [Cells] 2019 Sep 12; Vol. 8 (9). Date of Electronic Publication: 2019 Sep 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Extrinsic Apoptosis Pathway Altered by Glycogen Synthase Kinase-3 β Inhibitor Influences the Net Drug Effect on NSC-34 Motor Neuron-Like Cell Survival.

  • Authors : Kim JE; Department of Neurology, Seoul Medical Center, Seoul, Republic of Korea.; Lim JH

Subjects: Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/*drug therapy ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Glycogen Synthase Kinase 3 beta/Glycogen Synthase Kinase 3 beta/Glycogen Synthase Kinase 3 beta/*genetics

  • Source: BioMed research international [Biomed Res Int] 2017; Vol. 2017, pp. 4163839. Date of Electronic Publication: 2017 Sep 10.Publisher: Hindawi Pub. Co Country of Publication: United States NLM ID: 101600173 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS.

  • Authors : Ito Y; Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.; Ofengeim D

Subjects: Apoptosis*/Apoptosis*/Apoptosis*/genetics; Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/*pathology ; Axons/Axons/Axons/*pathology

  • Source: Science (New York, N.Y.) [Science] 2016 Aug 05; Vol. 353 (6299), pp. 603-8.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium:

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Academic Journal

A Chemical Screen Identifies Compounds Limiting the Toxicity of C9ORF72 Dipeptide Repeats.

  • Authors : Corman A; Science for Life Laboratory, Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 21 Stockholm, Sweden.; Jung B

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; C9orf72 Protein/C9orf72 Protein/C9orf72 Protein/*chemistry ; Peptides/Peptides/Peptides/*toxicityFrontotemporal Dementia With Motor Neuron Disease

  • Source: Cell chemical biology [Cell Chem Biol] 2019 Feb 21; Vol. 26 (2), pp. 235-243.e5. Date of Electronic Publication: 2018 Dec 06.Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  589 results for ""AMYOTROPHIC lateral sclerosis""