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Academic Journal

The dinitrobenzamide mustard prodrugs, PR-104A and SN27686, for use in a novel MNDEPT cancer prodrug therapy approach.

  • Authors : Ball P; School of Natural Sciences, Bangor University, Bangor, Gwynedd, Wales LL57 2UW, U.K.; Thompson E

Subjects: Prodrugs*/Prodrugs*/Prodrugs*/metabolism ; Prodrugs*/Prodrugs*/Prodrugs*/pharmacology ; Nitrogen Mustard Compounds*/Nitrogen Mustard Compounds*/Nitrogen Mustard Compounds*/metabolism

  • Source: Bioscience reports [Biosci Rep] 2023 Apr 26; Vol. 43 (4).Publisher: Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 8102797 Publication Model: Print Cited Medium:

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Academic Journal

Paraxylines A-G: Highly oxygenated preurianin-type limonoids with immunomodulatory TLR4 and cytotoxic activities from the stem bark of Dysoxylum parasiticum.

  • Authors : Naini AA; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor, 45363, Sumedang, West Java, Indonesia; Central Laboratory, Universitas Padjadjaran, Jatinangor, 45363, Sumedang, West Java, Indonesia.

Subjects: Limonins*/Limonins*/Limonins*/pharmacology ; Limonins*/Limonins*/Limonins*/chemistry ; Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/chemistry

  • Source: Phytochemistry [Phytochemistry] 2024 Apr; Vol. 220, pp. 114009. Date of Electronic Publication: 2024 Feb 09.Publisher: Elsevier Country of Publication: England NLM ID: 0151434 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3700

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Academic Journal

Three new cytotoxic annonaceous acetogenins from the seeds of Annona squamosa .

  • Authors : Ma C; Department of Clinical Pharmacology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.; Pharmaceutical Institute, Nanjing University of Chinese Medicine, Nanjing, China.

Subjects: Annona*/Annona*/Annona*/chemistry ; Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/chemistry ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

  • Source: Natural product research [Nat Prod Res] 2024 Apr; Vol. 38 (7), pp. 1135-1139. Date of Electronic Publication: 2022 Oct 19.Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Five undescribed aryltetralin lignans with cytotoxic activities from the fruits of Cleistanthus eberhardtii.

  • Authors : Nguyen LH; Institute of Marine Biochemistry of the Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam; Hanoi University of Pharmacy, 13 Le Thanh Tong, Hoankiem, Hanoi, Viet Nam.

Subjects: Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/pharmacology ; Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/chemistry ; Lignans*/Lignans*/Lignans*/pharmacology

  • Source: Fitoterapia [Fitoterapia] 2024 Mar; Vol. 173, pp. 105826. Date of Electronic Publication: 2024 Jan 12.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Chryroxosides A-E: five new triterpene saponins from the leaves of Chrysophyllum roxburghii G.Don. and their cytotoxic activity.

  • Authors : Hang PT; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, Hanoi, Vietnam.; Faculty of Chemistry, Graduate University of Science and Technology, Vietnam Academy of Science and Technology, Hanoi, Vietnam.

Subjects: Saponins*/Saponins*/Saponins*/pharmacology ; Saponins*/Saponins*/Saponins*/chemistry ; Triterpenes*/Triterpenes*/Triterpenes*/pharmacology

  • Source: Natural product research [Nat Prod Res] 2024 Feb-Mar; Vol. 38 (5), pp. 735-743. Date of Electronic Publication: 2023 Apr 06.Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

NMDA receptor signaling induces the chemoresistance of temozolomide via upregulation of MGMT expression in glioblastoma cells.

  • Authors : Tsuji S; Molecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University, Gifu, Japan.; Nakamura S

Subjects: Glioblastoma*/Glioblastoma*/Glioblastoma*/drug therapy ; Glioblastoma*/Glioblastoma*/Glioblastoma*/genetics ; Glioblastoma*/Glioblastoma*/Glioblastoma*/metabolism

  • Source: Journal of neuro-oncology [J Neurooncol] 2022 Nov; Vol. 160 (2), pp. 375-388. Date of Electronic Publication: 2022 Oct 29.Publisher: Springer Country of Publication: United States NLM ID: 8309335 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Conquering chemoresistance in pancreatic cancer: Exploring novel drug therapies and delivery approaches amidst desmoplasia and hypoxia.

  • Authors : Chintamaneni PK; Department of Pharmaceutics, GITAM School of Pharmacy, GITAM (Deemed to be University), Rudraram, 502329 Telangana, India. Electronic address: .; Pindiprolu SKSS

Subjects: Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/drug therapy ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/pathology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

  • Source: Cancer letters [Cancer Lett] 2024 Apr 28; Vol. 588, pp. 216782. Date of Electronic Publication: 2024 Mar 06.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Discovery of Selective and Potent ATR Degrader for Exploration its Kinase-Independent Functions in Acute Myeloid Leukemia Cells.

  • Authors : Wang Y; The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin, 300071, P. R. China.; Wang R

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/drug therapy ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/metabolism ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

  • Source: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Apr 22; Vol. 63 (17), pp. e202318568. Date of Electronic Publication: 2024 Mar 21.Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773

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Academic Journal

Tapcin, an In Vivo Active Dual Topoisomerase I/II Inhibitor Discovered by Synthetic Bioinformatic Natural Product (Syn-BNP)-Coupled Metagenomics.

  • Authors : Wang Z; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.; Kasper A

Subjects: Biological Products*/Biological Products*/Biological Products*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry

  • Source: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Apr 22; Vol. 63 (17), pp. e202317187. Date of Electronic Publication: 2024 Mar 20.Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773

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Academic Journal

Potentials and future perspectives of multi-target drugs in cancer treatment: the next generation anti-cancer agents.

  • Authors : Doostmohammadi A; Nervous System Stem Cells Research Center, Semnan University of Medical Sciences, Semnan, Iran.; Student Research Committee, Semnan University of Medical Sciences, Semnan, Iran.

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Neoplasms*/Neoplasms*/Neoplasms*/drug therapy

  • Source: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Apr 15; Vol. 22 (1), pp. 228. Date of Electronic Publication: 2024 Apr 15.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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  • 10-20 of  790,998 results for ""ANTINEOPLASTIC agents""