Charleston County Public Library

Item request has been placed!

Item request cannot be made.

Processing Request

Academic Journal

A Novel Approach for Glioblastoma Treatment by Combining Apoptosis Inducers (TMZ, MTX, and Cytarabine) with E.V.A. (Eltanexor, Venetoclax, and A1210477) Inhibiting XPO1, Bcl-2, and Mcl-1.

Authors : Zhao K; Department of Neurosurgery, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.; Department of Hematology, Oncology & Immunology, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.

Subjects: Glioblastoma*/Glioblastoma*/Glioblastoma*/drug therapy ; Glioblastoma*/Glioblastoma*/Glioblastoma*/metabolism ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

Source: Cells [Cells] 2024 Apr 04; Vol. 13 (7). Date of Electronic Publication: 2024 Apr 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

Record details

Read More Add to Saved list

Academic Journal

A chloromethyl-triazole fluorescent chemosensor for O 6 -methylguanine DNA methyltransferase.

Authors : Ayan S; Department of Chemical and Physical Sciences, University of Toronto Mississauga, Mississauga, Ontario, L5L 1C6, Canada. .; Rotaru AM

Subjects: Antineoplastic Agents*; Guanine/Guanine/Guanine/*analogs & derivatives; Temozolomide

Source: Organic & biomolecular chemistry [Org Biomol Chem] 2024 Apr 03; Vol. 22 (14), pp. 2749-2753. Date of Electronic Publication: 2024 Apr 03.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101154995 Publication Model: Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Tarlatamab for Patients with Previously Treated Small-Cell Lung Cancer.

Authors : Ahn MJ; DeLLphi-301 Investigators

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/drug therapy ; Small Cell Lung Carcinoma*/Small Cell Lung Carcinoma*/Small Cell Lung Carcinoma*/drug therapy

Source: The New England journal of medicine [N Engl J Med] 2023 Nov 30; Vol. 389 (22), pp. 2063-2075. Date of Electronic Publication: 2023 Oct 20.Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print-Electronic Cited Medium:

Record details

Read More Add to Saved list

Academic Journal

Synergistic effect of cryptotanshinone and temozolomide treatment against human glioblastoma cells.

Authors : Zhu S; Brain Research Institute, Research Center of Neurological Diseases, Taihe Hospital, Hubei University of Medicine, 32 Renmin South Rd, Shiyan, 442000, Hubei, China.; Guo J

Subjects: Glioblastoma*/Glioblastoma*/Glioblastoma*/genetics ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Brain Neoplasms*/Brain Neoplasms*/Brain Neoplasms*/genetics

Source: Scientific reports [Sci Rep] 2023 Dec 09; Vol. 13 (1), pp. 21835. Date of Electronic Publication: 2023 Dec 09.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Magnetic Resonance Imaging of Iron Metabolism with T2* Mapping Predicts an Enhanced Clinical Response to Pharmacologic Ascorbate in Patients with GBM.

Authors : Petronek MS; Department of Radiation Oncology, University of Iowa, Iowa City, Iowa.; Monga V

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Brain Neoplasms*/Brain Neoplasms*/Brain Neoplasms*/drug therapy ; Glioblastoma*/Glioblastoma*/Glioblastoma*/diagnostic imaging

Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Jan 17; Vol. 30 (2), pp. 283-293.Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265

Record details

Read More Add to Saved list

Academic Journal

Phase 1 dose-escalation study evaluating the safety, pharmacokinetics, and clinical activity of OBI-3424 in patients with advanced or metastatic solid tumors.

Authors : Tsimberidou AM; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. .; Verschraegen CF

Subjects: Anemia*/Anemia*/Anemia*/chemically induced ; Anemia*/Anemia*/Anemia*/drug therapy ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/adverse effects

Source: British journal of cancer [Br J Cancer] 2023 Aug; Vol. 129 (2), pp. 266-274. Date of Electronic Publication: 2023 May 12.Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited

Record details

Read More Add to Saved list

Academic Journal

Study on the activation of cell death mechanisms: in search of new therapeutic targets in glioblastoma multiforme.

Authors : Gaiaschi L; Laboratory of Cell Biology and Neurobiology, Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, Via Ferrata 9, 27100, Pavia, Italy. .; Favaron C

Subjects: Glioblastoma*/Glioblastoma*/Glioblastoma*/drug therapy ; Glioblastoma*/Glioblastoma*/Glioblastoma*/genetics ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

Source: Apoptosis : an international journal on programmed cell death [Apoptosis] 2023 Aug; Vol. 28 (7-8), pp. 1241-1257. Date of Electronic Publication: 2023 May 27.Publisher: Springer Country of Publication: Netherlands NLM ID: 9712129 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Discovery of new imidazotetrazinones with potential to overcome tumor resistance.

Authors : Summers HS; School of Chemistry, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.; Lewis W

Subjects: Antineoplastic Agents* ; Brain Neoplasms*/Brain Neoplasms*/Brain Neoplasms*/drug therapy ; Glioblastoma*/Glioblastoma*/Glioblastoma*/drug therapy

Source: European journal of medicinal chemistry [Eur J Med Chem] 2023 Sep 05; Vol. 257, pp. 115507. Date of Electronic Publication: 2023 May 21.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list

Academic Journal

From plant to cancer drug: lessons learned from the discovery of taxol.

Authors : Cech NB; University of North Carolina Greensboro, USA. .; Oberlies NH

Subjects: Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/pharmacology ; Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/chemistry ; Biological Products*/Biological Products*/Biological Products*/chemistry

Source: Natural product reports [Nat Prod Rep] 2023 Jul 19; Vol. 40 (7), pp. 1153-1157. Date of Electronic Publication: 2023 Jul 19.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 8502408 Publication Model: Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Adherence to oral hormonal anticancer agents in breast cancer.

Authors : Gori S; Oncology Department, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy.; Modena A

Subjects: Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/drug therapy ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Mouth Neoplasms*

Source: Tumori [Tumori] 2023 Jun; Vol. 109 (3), pp. 262-268. Date of Electronic Publication: 2022 May 21.Publisher: Sage Publications Country of Publication: United States NLM ID: 0111356 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

The dinitrobenzamide mustard prodrugs, PR-104A and SN27686, for use in a novel MNDEPT cancer prodrug therapy approach.

Authors : Ball P; School of Natural Sciences, Bangor University, Bangor, Gwynedd, Wales LL57 2UW, U.K.; Thompson E

Subjects: Prodrugs*/Prodrugs*/Prodrugs*/metabolism ; Prodrugs*/Prodrugs*/Prodrugs*/pharmacology ; Nitrogen Mustard Compounds*/Nitrogen Mustard Compounds*/Nitrogen Mustard Compounds*/metabolism

Source: Bioscience reports [Biosci Rep] 2023 Apr 26; Vol. 43 (4).Publisher: Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 8102797 Publication Model: Print Cited Medium:

Record details

Read More Add to Saved list

Academic Journal

Paraxylines A-G: Highly oxygenated preurianin-type limonoids with immunomodulatory TLR4 and cytotoxic activities from the stem bark of Dysoxylum parasiticum.

Authors : Naini AA; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor, 45363, Sumedang, West Java, Indonesia; Central Laboratory, Universitas Padjadjaran, Jatinangor, 45363, Sumedang, West Java, Indonesia.

Subjects: Limonins*/Limonins*/Limonins*/pharmacology ; Limonins*/Limonins*/Limonins*/chemistry ; Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/chemistry

Source: Phytochemistry [Phytochemistry] 2024 Apr; Vol. 220, pp. 114009. Date of Electronic Publication: 2024 Feb 09.Publisher: Elsevier Country of Publication: England NLM ID: 0151434 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3700

Record details

Read More Add to Saved list

Academic Journal

Three new cytotoxic annonaceous acetogenins from the seeds of Annona squamosa .

Authors : Ma C; Department of Clinical Pharmacology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.; Pharmaceutical Institute, Nanjing University of Chinese Medicine, Nanjing, China.

Subjects: Annona*/Annona*/Annona*/chemistry ; Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/chemistry ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

Source: Natural product research [Nat Prod Res] 2024 Apr; Vol. 38 (7), pp. 1135-1139. Date of Electronic Publication: 2022 Oct 19.Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list

Academic Journal

Five undescribed aryltetralin lignans with cytotoxic activities from the fruits of Cleistanthus eberhardtii.

Authors : Nguyen LH; Institute of Marine Biochemistry of the Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam; Hanoi University of Pharmacy, 13 Le Thanh Tong, Hoankiem, Hanoi, Viet Nam.

Source: Fitoterapia [Fitoterapia] 2024 Mar; Vol. 173, pp. 105826. Date of Electronic Publication: 2024 Jan 12.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Chryroxosides A-E: five new triterpene saponins from the leaves of Chrysophyllum roxburghii G.Don. and their cytotoxic activity.

Authors : Hang PT; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, Hanoi, Vietnam.; Faculty of Chemistry, Graduate University of Science and Technology, Vietnam Academy of Science and Technology, Hanoi, Vietnam.

Subjects: Saponins*/Saponins*/Saponins*/pharmacology ; Saponins*/Saponins*/Saponins*/chemistry ; Triterpenes*/Triterpenes*/Triterpenes*/pharmacology

Source: Natural product research [Nat Prod Res] 2024 Feb-Mar; Vol. 38 (5), pp. 735-743. Date of Electronic Publication: 2023 Apr 06.Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list

Academic Journal

NMDA receptor signaling induces the chemoresistance of temozolomide via upregulation of MGMT expression in glioblastoma cells.

Authors : Tsuji S; Molecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University, Gifu, Japan.; Nakamura S

Subjects: Glioblastoma*/Glioblastoma*/Glioblastoma*/drug therapy ; Glioblastoma*/Glioblastoma*/Glioblastoma*/genetics ; Glioblastoma*/Glioblastoma*/Glioblastoma*/metabolism

Source: Journal of neuro-oncology [J Neurooncol] 2022 Nov; Vol. 160 (2), pp. 375-388. Date of Electronic Publication: 2022 Oct 29.Publisher: Springer Country of Publication: United States NLM ID: 8309335 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Conquering chemoresistance in pancreatic cancer: Exploring novel drug therapies and delivery approaches amidst desmoplasia and hypoxia.

Authors : Chintamaneni PK; Department of Pharmaceutics, GITAM School of Pharmacy, GITAM (Deemed to be University), Rudraram, 502329 Telangana, India. Electronic address: .; Pindiprolu SKSS

Subjects: Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/drug therapy ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/pathology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

Source: Cancer letters [Cancer Lett] 2024 Apr 28; Vol. 588, pp. 216782. Date of Electronic Publication: 2024 Mar 06.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Discovery of Selective and Potent ATR Degrader for Exploration its Kinase-Independent Functions in Acute Myeloid Leukemia Cells.

Authors : Wang Y; The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin, 300071, P. R. China.; Wang R

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/drug therapy ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/metabolism ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

Source: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Apr 22; Vol. 63 (17), pp. e202318568. Date of Electronic Publication: 2024 Mar 21.Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773

Record details

Read More Add to Saved list

Academic Journal

Tapcin, an In Vivo Active Dual Topoisomerase I/II Inhibitor Discovered by Synthetic Bioinformatic Natural Product (Syn-BNP)-Coupled Metagenomics.

Authors : Wang Z; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.; Kasper A

Subjects: Biological Products*/Biological Products*/Biological Products*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry

Source: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Apr 22; Vol. 63 (17), pp. e202317187. Date of Electronic Publication: 2024 Mar 20.Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773

Record details

Read More Add to Saved list

Academic Journal

Narazaciclib, a novel multi-kinase inhibitor with potent activity against CSF1R, FLT3 and CDK6, shows strong anti-AML activity in defined preclinical models.

Authors : Yang T; Hanx Biopharmaceuticals, Ltd., Wuhan, Hubei, PRC, China.; Ke H

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/pathology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use

Source: Scientific reports [Sci Rep] 2024 Apr 19; Vol. 14 (1), pp. 9032. Date of Electronic Publication: 2024 Apr 19.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Click-Capable Phenanthriplatin Derivatives as Tools to Study Pt(II)-Induced Nucleolar Stress.

Authors : O'Dowd PD; Department of Chemistry, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland.; SSPC, The Science Foundation Ireland Research Centre for Pharmaceuticals, Limerick V94 T9PX, Ireland.

Subjects: Organoplatinum Compounds*/Organoplatinum Compounds*/Organoplatinum Compounds*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/metabolism

Source: ACS chemical biology [ACS Chem Biol] 2024 Apr 19; Vol. 19 (4), pp. 875-885. Date of Electronic Publication: 2024 Mar 14.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list

Academic Journal

Characterizing heterogeneous single-cell dose responses computationally and experimentally using threshold inhibition surfaces and dose-titration assays.

Authors : Kinnunen PC; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.; Humphries BA

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/drug therapy

Source: NPJ systems biology and applications [NPJ Syst Biol Appl] 2024 Apr 18; Vol. 10 (1), pp. 42. Date of Electronic Publication: 2024 Apr 18.Publisher: Nature Publishing Group in partnership with SBI, The Systems Biology Institute Country of Publication: England NLM ID: 101677786 Publication Model:

Record details

Read More Add to Saved list

Academic Journal

Overall Survival with Adjuvant Pembrolizumab in Renal-Cell Carcinoma.

Authors : Choueiri TK; KEYNOTE-564 Investigators

Subjects: Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/drug therapy ; Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/mortality ; Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/surgery

Source: The New England journal of medicine [N Engl J Med] 2024 Apr 18; Vol. 390 (15), pp. 1359-1371.Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Light-Activatable Photocaged UNC2025 for Triggering TAM Kinase Inhibition in Bladder Cancer.

Authors : Breton-Patient C; Institut Curie, Université PSL CNRS UMR9187, Inserm U119, 91400, Orsay, France.; Université Paris-Saclay CNRS UMR9187, Inserm U119, 91400, Orsay, France.

Source: Chembiochem : a European journal of chemical biology [Chembiochem] 2024 Apr 16; Vol. 25 (8), pp. e202300855. Date of Electronic Publication: 2024 Mar 18.Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 100937360 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Potentials and future perspectives of multi-target drugs in cancer treatment: the next generation anti-cancer agents.

Authors : Doostmohammadi A; Nervous System Stem Cells Research Center, Semnan University of Medical Sciences, Semnan, Iran.; Student Research Committee, Semnan University of Medical Sciences, Semnan, Iran.

Source: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Apr 15; Vol. 22 (1), pp. 228. Date of Electronic Publication: 2024 Apr 15.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

Record details

Read More Add to Saved list

Academic Journal

Schiff bases and their metal complexes to target and overcome (multidrug) resistance in cancer.

Authors : Podolski-Renić A; Department of Neurobiology, Institute for Biological Research 'Siniša Stanković' - National Institute of Republic of Serbia, University of Belgrade, Serbia.; Čipak Gašparović A

Subjects: Coordination Complexes*/Coordination Complexes*/Coordination Complexes*/pharmacology ; Coordination Complexes*/Coordination Complexes*/Coordination Complexes*/chemistry ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 Apr 15; Vol. 270, pp. 116363. Date of Electronic Publication: 2024 Mar 29.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list

Academic Journal

Synthesis and biological evaluation of 4-imidazolidinone-containing compounds as potent inhibitors of the MDM2/p53 interaction.

Authors : Lin Z; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, 210023, China; State Key Laboratory of Drug Research and Small-Molecule Drug Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road Shanghai, 201203, China.

Subjects: Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/metabolism ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry

Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 Apr 15; Vol. 270, pp. 116366. Date of Electronic Publication: 2024 Apr 02.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list

Academic Journal

Co-Assembly of Cancer Drugs with Cyclo-HH Peptides: Insights from Simulations and Experiments.

Authors : Vlachou A; Artie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, Texas 77843-3122, United States.; Kumar VB

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry ; Neoplasms*/Neoplasms*/Neoplasms*/drug therapy

Source: ACS applied bio materials [ACS Appl Bio Mater] 2024 Apr 15; Vol. 7 (4), pp. 2309-2324. Date of Electronic Publication: 2024 Mar 13.Publisher: ACS Publications Country of Publication: United States NLM ID: 101729147 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Respiratory complex I regulates dendritic cell maturation in explant model of human tumor immune microenvironment.

Authors : Turpin R; Translational Cancer Medicine, University of Helsinki, Helsinki, Finland.; Liu R

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Breast Neoplasms*

Source: Journal for immunotherapy of cancer [J Immunother Cancer] 2024 Apr 11; Vol. 12 (4). Date of Electronic Publication: 2024 Apr 11.Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Developing a Copper(II) Isopropyl 2-Pyridyl Ketone Thiosemicarbazone Compound Based on the IB Subdomain of Human Serum Albumin-Indomethacin Complex: Inhibiting Tumor Growth by Remodeling the Tumor Microenvironment.

Authors : Man X; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources/Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), School of Chemistry and Pharmaceutical Sciences, Collaborative Innovation Center for Guangxi Ethnic Medicine, Guangxi Normal University, Guilin, Guangxi 541004, China.; Li S

Subjects: Thiosemicarbazones*/Thiosemicarbazones*/Thiosemicarbazones*/pharmacology ; Thiosemicarbazones*/Thiosemicarbazones*/Thiosemicarbazones*/therapeutic use ; Prodrugs*/Prodrugs*/Prodrugs*/pharmacology

Source: Journal of medicinal chemistry [J Med Chem] 2024 Apr 11; Vol. 67 (7), pp. 5744-5757. Date of Electronic Publication: 2024 Mar 29.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list

Academic Journal

Copper(II) Complexes with 2,2':6',2″-Terpyridine Derivatives Displaying Dimeric Dichloro-μ-Bridged Crystal Structure: Biological Activities from 2D and 3D Tumor Spheroids to In Vivo Models.

Authors : Choroba K; Institute of Chemistry, University of Silesia, Szkolna 9, 40-006 Katowice, Poland.; Machura B

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry ; Ovarian Neoplasms*

Source: Journal of medicinal chemistry [J Med Chem] 2024 Apr 11; Vol. 67 (7), pp. 5813-5836. Date of Electronic Publication: 2024 Mar 22.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list

Academic Journal

Combined therapy of dabrafenib and an anti-HER2 antibody-drug conjugate for advanced BRAF-mutant melanoma.

Authors : Li W; Department of General Surgery, First Affiliated Hospital, Gannan Medical University, Ganzhou, 341000, China.; Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases (Ministry of Education), Gannan Medical University, 1 Hexie Road, Rongjiang New District, Ganzhou, 341000, China.

Subjects: Melanoma*/Melanoma*/Melanoma*/drug therapy ; Melanoma*/Melanoma*/Melanoma*/genetics ; Skin Neoplasms*/Skin Neoplasms*/Skin Neoplasms*/genetics

Source: Cellular & molecular biology letters [Cell Mol Biol Lett] 2024 Apr 10; Vol. 29 (1), pp. 50. Date of Electronic Publication: 2024 Apr 10.Publisher: BioMed Central Country of Publication: England NLM ID: 9607427 Publication Model: Electronic Cited Medium: Internet ISSN: 1689-1392

Record details

Read More Add to Saved list

Academic Journal

pHLIP targeted intracellular delivery of calicheamicin.

Authors : DuPont M; Physics Department, University of Rhode Island, Kingston, RI, USA.; Klumpp C

Source: International journal of pharmaceutics [Int J Pharm] 2024 Apr 10; Vol. 654, pp. 123954. Date of Electronic Publication: 2024 Feb 28.Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium:

Record details

Read More Add to Saved list

Academic Journal

Autophagy-driven regulation of cisplatin response in human cancers: Exploring molecular and cell death dynamics.

Authors : Yang Y; Hebei Key Laboratory of Cancer Radiotherapy and Chemotherapy, Department of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, Hebei, China.; Liu L

Source: Cancer letters [Cancer Lett] 2024 Apr 10; Vol. 587, pp. 216659. Date of Electronic Publication: 2024 Feb 15.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Development of an aptamer capable of multidrug resistance reversal for tumor combination chemotherapy.

Authors : Wen X; State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan University, Changsha 410082, China.; College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China.

Subjects: Drug Resistance, Neoplasm* ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Apr 09; Vol. 121 (15), pp. e2321116121. Date of Electronic Publication: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list

Academic Journal

Ultrastable Iodinated Oil-Based Pickering Emulsion Enables Locoregional Sustained Codelivery of Hypoxia Inducible Factor-1 Inhibitor and Anticancer Drugs for Tumor Combination Chemotherapy.

Authors : Li Z; Shenzhen Key Laboratory of Smart Healthcare Engineering, Guangdong Provincial Key Laboratory of Advanced Biomaterials, Department of Biomedical Engineering, Southern University of Science and Technology, Shenzhen 518055, China.; Liu X

Source: ACS biomaterials science & engineering [ACS Biomater Sci Eng] 2024 Apr 08; Vol. 10 (4), pp. 2270-2281. Date of Electronic Publication: 2024 Mar 27.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101654670 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list

Academic Journal

Agnostic Administration of Targeted Anticancer Drugs: Looking for a Balance between Hype and Caution.

Authors : Aleksakhina SN; Department of Tumor Growth Biology, N. N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.; Ivantsov AO

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 07; Vol. 25 (7). Date of Electronic Publication: 2024 Apr 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

Record details

Read More Add to Saved list

Academic Journal

Augmenting Cancer Therapy with a Supramolecular Immunogenic Cell Death Inducer: A Lysosome-Targeted NIR-Light-Activated Ruthenium(II) Metallacycle.

Authors : Tu L; National Key Laboratory of Green Pesticide, International Joint Research Center for Intelligent Biosensor Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, China.; Li C

Subjects: Ruthenium*/Ruthenium*/Ruthenium*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use

Source: Journal of the American Chemical Society [J Am Chem Soc] 2024 Apr 03; Vol. 146 (13), pp. 8991-9003. Date of Electronic Publication: 2024 Mar 21.Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list

Academic Journal

Ganoderic acid A suppresses autophagy by regulating the circFLNA/miR-486-3p/CYP1A1/XRCC1 axis to strengthen the sensitivity of lung cancer cells to cisplatin.

Authors : Gong E; Respiratory Department, The Sixth Affiliated Hospital of Wenzhou Medical University, 15# Dazhong Street, Liandu District, Lishui City, Zhejiang Province, China.; Pan J

Source: The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2024 Apr 03; Vol. 76 (4), pp. 354-367.Publisher: Oxford University Press Country of Publication: England NLM ID: 0376363 Publication Model: Print Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Lapatinib antitumor effect is associated with PI3K and MAPK pathway: An analysis in human and canine prostate cancer cells.

Authors : Fonseca-Alves CE; Department of Veterinary Surgery and Animal Reproduction, São Paulo State University-UNESP, Botucatu-SP, Brazil.; Institute of Health Sciences, Paulista University-UNIP, Bauru-SP, 17048-290, Brazil.

Source: PloS one [PLoS One] 2024 Apr 02; Vol. 19 (4), pp. e0297043. Date of Electronic Publication: 2024 Apr 02 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

Record details

Read Online Read More Add to Saved list

Academic Journal

B-Myb deficiency boosts bortezomib-induced immunogenic cell death in colorectal cancer.

Authors : Hui YJ; Department of Hepatobiliary Surgery, Renmin Hospital of Wuhan University, Jiefang Road No. 238, Wuhan, 430060, Hubei Province, China.; Department of General Surgery, Taihe Hospital, Hubei University of Medicine, Renmin South Road No. 32, Shiyan, 442000, Hubei Province, China.

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/drug therapy

Source: Scientific reports [Sci Rep] 2024 Apr 02; Vol. 14 (1), pp. 7733. Date of Electronic Publication: 2024 Apr 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Regorafenib and glioblastoma: a literature review of preclinical studies, molecular mechanisms and clinical effectiveness.

Authors : Mongiardi MP; Institute of Biochemistry and Cell Biology, IBBC-CNR, Monterotondo, Rome, Italy.; Pallini R

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Glioblastoma*/Glioblastoma*/Glioblastoma*/drug therapy

Source: Expert reviews in molecular medicine [Expert Rev Mol Med] 2024 Apr 02; Vol. 26, pp. e5. Date of Electronic Publication: 2024 Apr 02.Publisher: Published by Cambridge University Press in association with the Clinical and Biomedical Computing Unit of the University of Cambridge School of Clinical Medicine

Record details

Read More Add to Saved list

Academic Journal

An immunogenic anti-cancer stem cell bi-nuclear copper(II)-flufenamic acid complex.

Authors : Li Y; School of Chemistry, University of Leicester, Leicester, LE1 7RH, UK. .; Fang J

Subjects: Coordination Complexes*/Coordination Complexes*/Coordination Complexes*/pharmacology ; Coordination Complexes*/Coordination Complexes*/Coordination Complexes*/metabolism ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

Source: Dalton transactions (Cambridge, England : 2003) [Dalton Trans] 2024 Apr 02; Vol. 53 (14), pp. 6410-6415. Date of Electronic Publication: 2024 Apr 02.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101176026 Publication Model: Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Biomarkers for Antibody-Drug Conjugates in Solid Tumors.

Authors : Katrini J; Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Milan, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.

Subjects: Immunoconjugates*/Immunoconjugates*/Immunoconjugates*/pharmacology ; Immunoconjugates*/Immunoconjugates*/Immunoconjugates*/therapeutic use ; Neoplasms*

Source: Molecular cancer therapeutics [Mol Cancer Ther] 2024 Apr 02; Vol. 23 (4), pp. 436-446.Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium:

Record details

Read More Add to Saved list

Academic Journal

Elimusertib has Antitumor Activity in Preclinical Patient-Derived Pediatric Solid Tumor Models.

Authors : Pusch FF; Experimental and Clinical Research Center (ECRC) of the MDC and Charité Berlin, Berlin, Germany.; Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.

Subjects: Neoplasms*/Neoplasms*/Neoplasms*/drug therapy ; Neoplasms*/Neoplasms*/Neoplasms*/pathology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

Source: Molecular cancer therapeutics [Mol Cancer Ther] 2024 Apr 02; Vol. 23 (4), pp. 507-519.Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium:

Record details

Read More Add to Saved list

Academic Journal

New insights into the anticancer therapeutic potential of icaritin and its synthetic derivatives.

Authors : Reyes-Hernández OD; Laboratorio de Biología Molecular del Cáncer, UMIEZ, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Ciudad de México, Mexico.; Figueroa-González G

Subjects: Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/drug therapy ; Liver Neoplasms*/Liver Neoplasms*/Liver Neoplasms*/drug therapy ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

Source: Drug development research [Drug Dev Res] 2024 Apr; Vol. 85 (2), pp. e22175.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8204468 Publication Model: Print Cited Medium: Internet ISSN: 1098-2299

Record details

Read More Add to Saved list

Academic Journal

Tenovin 3 induces apoptosis and ferroptosis in EGFR 19del non small cell lung cancer cells.

Authors : Lv S; The Fifth Affiliated Hospital,Guangdong Province & NMPA & State Key Laboratory,School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China.; Pan Q

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/genetics ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/metabolism

Source: Scientific reports [Sci Rep] 2024 Apr 01; Vol. 14 (1), pp. 7654. Date of Electronic Publication: 2024 Apr 01.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Quantification of Unencapsulated Drug in Target Tissues Demonstrates Pharmacological Properties and Therapeutic Effects of Liposomal Topotecan (FF-10850).

Authors : Kimura T; Bio Science & Engineering Laboratories, FUJIFILM Corporation, 577 Ushijima, Kaisei-Machi, Ashigarakami-Gun, Kanagawa, 258-8577, Japan. .; Okada K

Subjects: Neoplasms*/Neoplasms*/Neoplasms*/drug therapy ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use

Source: Pharmaceutical research [Pharm Res] 2024 Apr; Vol. 41 (4), pp. 795-806. Date of Electronic Publication: 2024 Mar 27.Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Print-Electronic Cited Medium:

Record details

Read More Add to Saved list

Academic Journal

Ginsenoside Rg5 as an anticancer drug: a comprehensive review on mechanisms, structure-activity relationship, and prospects for clinical advancement.

Authors : Elsaman T; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Al Jouf, Saudi Arabia.; Muddathir AM

Subjects: Ginsenosides*/Ginsenosides*/Ginsenosides*/pharmacology ; Ginsenosides*/Ginsenosides*/Ginsenosides*/therapeutic use ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

Source: Pharmacological reports : PR [Pharmacol Rep] 2024 Apr; Vol. 76 (2), pp. 287-306. Date of Electronic Publication: 2024 Mar 25.Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101234999 Publication Model: Print-Electronic Cited Medium:

Record details

Read More Add to Saved list

Academic Journal

Pioneering the Way: The Revolutionary Potential of Antibody-Drug Conjugates in NSCLC.

Authors : Chen X; Department of Geriatric Medicine, Shenzhen Longhua District Central Hospital, Shenzhen, 518110, China.; Zeng C

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Immunoconjugates*/Immunoconjugates*/Immunoconjugates*/therapeutic use ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

Source: Current treatment options in oncology [Curr Treat Options Oncol] 2024 Apr; Vol. 25 (4), pp. 556-584. Date of Electronic Publication: 2024 Mar 23.Publisher: Current Science, Inc Country of Publication: United States NLM ID: 100900946 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list

Patron Login

menu

Search Results

Your Filters

Engage with CCPL

Contact CCPL