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Academic Journal

BET protein degradation triggers DR5-mediated immunogenic cell death to suppress colorectal cancer and potentiate immune checkpoint blockade.

  • Authors : Tong J; UPMC Hillman Cancer Center, Pittsburgh, PA, 15213, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA.

Subjects: Gene Expression Regulation, Neoplastic* ; Immunogenic Cell Death*; Biomarkers, Tumor/Biomarkers, Tumor/Biomarkers, Tumor/*metabolism

  • Source: Oncogene [Oncogene] 2021 Dec; Vol. 40 (48), pp. 6566-6578. Date of Electronic Publication: 2021 Oct 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repression.

  • Authors : Shi C; Cancer Centre, Faculty of Health Sciences, University of Macau, Avenida da Universidade, Taipa, Macau SAR, China.; Yang EJ

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*drug therapy ; Proteins/Proteins/Proteins/*genetics

  • Source: Oncogene [Oncogene] 2021 Feb; Vol. 40 (5), pp. 937-950. Date of Electronic Publication: 2020 Dec 08.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The inhibitors of apoptosis: there is more to life than Bcl2.

  • Authors : Liston P; Children's Hospital of Eastern Ontario, Research Institute, 401 Smyth Raod, Ottawa, Canada K1H 8L1.; Fong WG

Subjects: Apoptosis*; Nerve Tissue Proteins/Nerve Tissue Proteins/Nerve Tissue Proteins/*physiology ; Proteins/Proteins/Proteins/*physiology

  • Source: Oncogene [Oncogene] 2003 Nov 24; Vol. 22 (53), pp. 8568-80.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232

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Academic Journal

BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition.

  • Authors : Zhang B; Faculty of Health Sciences, University of Macau, Avenida da Universidade, Taipa, 999078, Macau, SAR, China.; Lyu J

Subjects: BRCA1 Protein/BRCA1 Protein/BRCA1 Protein/*deficiency ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*pathology ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology

  • Source: Oncogene [Oncogene] 2018 Dec; Vol. 37 (49), pp. 6341-6356. Date of Electronic Publication: 2018 Jul 24.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Induction and endoplasmic reticulum location of BIK/NBK in response to apoptotic signaling by E1A and p53.

  • Authors : Mathai JP; Department of Biochemistry, McIntyre Medical Sciences Building, McGill University, 3655 Promenade Sir William Osler, Montreal, Quebec, Canada H3G 1Y6.; Germain M

Subjects: Apoptosis* ; Membrane Proteins* ; Protein Biosynthesis*

  • Source: Oncogene [Oncogene] 2002 Apr 11; Vol. 21 (16), pp. 2534-44.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232

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Academic Journal

Interchangeable binding of Bcl10 to TRAF2 and cIAPs regulates apoptosis signaling.

  • Authors : Yui D; Department of Anatomy and Neuroscience, Graduate School of Medicine, Osaka University. 2-2 Yamadaoka Suita, Osaka 565-0871, Japan. ; Yoneda T

Subjects: Adaptor Proteins, Signal Transducing* ; Apoptosis* ; Signal Transduction*

  • Source: Oncogene [Oncogene] 2001 Jul 19; Vol. 20 (32), pp. 4317-23.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232

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Academic Journal

Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death.

  • Authors : Holcik M; Apoptogen Inc., 401 Smyth Road, Ottawa, Ontario, K1H 8L1, Canada.; Yeh C

Subjects: Apoptosis* ; Gamma Rays*; Proteins/Proteins/Proteins/*metabolism

  • Source: Oncogene [Oncogene] 2000 Aug 24; Vol. 19 (36), pp. 4174-7.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232

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Academic Journal

Death associated proteins (DAPs): from gene identification to the analysis of their apoptotic and tumor suppressive functions.

  • Authors : Levy-Strumpf N; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.; Kimchi A

Subjects: Apoptosis*/Apoptosis*/Apoptosis*/genetics ; DNA-Binding Proteins* ; Drosophila Proteins*

  • Source: Oncogene [Oncogene] 1998 Dec 24; Vol. 17 (25), pp. 3331-40.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232

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Academic Journal

The inhibitors of apoptosis (IAPs) and their emerging role in cancer.

  • Authors : LaCasse EC; Apoptogen Inc, CHEO Research Institute, Ottawa, Ontario, Canada.; Baird S

Subjects: Apoptosis* ; Microtubule-Associated Proteins*; Neoplasms/Neoplasms/Neoplasms/*genetics

  • Source: Oncogene [Oncogene] 1998 Dec 24; Vol. 17 (25), pp. 3247-59.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232

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Academic Journal

The LIM protein AJUBA promotes colorectal cancer cell survival through suppression of JAK1/STAT1/IFIT2 network.

  • Authors : Jia H; Hongqiao Institute of Medicine, Shanghai Tongren Hospital/Faculty of Basic Medicine, Shanghai Jiaotong University School of Medicine, Shanghai, China.; Digestive Endoscopy Center, Shanghai Tongren Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Subjects: Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*genetics ; Janus Kinase 1/Janus Kinase 1/Janus Kinase 1/*genetics ; LIM Domain Proteins/LIM Domain Proteins/LIM Domain Proteins/*genetics

  • Source: Oncogene [Oncogene] 2017 May 11; Vol. 36 (19), pp. 2655-2666. Date of Electronic Publication: 2016 Nov 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  428 results for ""APOPTOSIS""