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Academic Journal

A bromodomain-independent mechanism of gene regulation by the BET inhibitor JQ1: direct activation of nuclear receptor PXR.

  • Authors : Huber AD; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.; Poudel S

Subjects: Azepines*/Azepines*/Azepines*/chemistry ; Azepines*/Azepines*/Azepines*/pharmacology ; Pregnane X Receptor*/Pregnane X Receptor*/Pregnane X Receptor*/chemistry

  • Source: Nucleic acids research [Nucleic Acids Res] 2024 Feb 28; Vol. 52 (4), pp. 1661-1676.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Suvorexant alters dynamics of the sleep-electroencephalography-power spectrum and depressive-symptom trajectories during inpatient opioid withdrawal.

  • Authors : Reid MJ; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Dunn KE

Subjects: Analgesics, Opioid*/Analgesics, Opioid*/Analgesics, Opioid*/therapeutic use ; Substance Withdrawal Syndrome* ; Azepines*

  • Source: Sleep [Sleep] 2024 Apr 12; Vol. 47 (4).Publisher: Oxford University Press Country of Publication: United States NLM ID: 7809084 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Efficacy and Safety of Transitioning to Lemborexant from Z-drug, Suvorexant, and Ramelteon in Japanese Insomnia Patients: An Open-label, Multicenter Study.

  • Authors : Ozone M; Department of Neuropsychiatry, Kurume University School of Medicine, 67 Asahi-machi, Kurume-shi, Fukuoka, Japan. .; Hirota S

Subjects: Sleep Initiation and Maintenance Disorders*/Sleep Initiation and Maintenance Disorders*/Sleep Initiation and Maintenance Disorders*/drug therapy ; Triazoles* ; Azepines*

  • Source: Advances in therapy [Adv Ther] 2024 Apr; Vol. 41 (4), pp. 1728-1745. Date of Electronic Publication: 2024 Mar 09.Publisher: Health Communications Inc Country of Publication: United States NLM ID: 8611864 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Suvorexant improves mitochondrial dynamics with the regulation of orexinergic and mTOR activation in rats exhibiting PTSD-like symptoms.

  • Authors : Prajapati SK; Neurotherapeutics Laboratory, Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi 221 005, U.P., India; Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, FL 33613, USA.

Subjects: Stress Disorders, Post-Traumatic* ; Azepines* ; Triazoles*

  • Source: Journal of affective disorders [J Affect Disord] 2024 Apr 01; Vol. 350, pp. 24-38. Date of Electronic Publication: 2024 Jan 06.Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7906073 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Is schedule IV suvorexant an appropriate reference drug of abuse to use in preclinical abuse liability testing in the rat?

  • Authors : Teuns GBA; Global Toxicology and Safety Pharmacology, Janssen Pharmaceutica NV, R&D, Turnhoutseweg 30, 2340, Beerse, Belgium. Electronic address: .; Tessari M

Subjects: Orexin Receptor Antagonists*/Orexin Receptor Antagonists*/Orexin Receptor Antagonists*/pharmacology ; Azepines*/Azepines*/Azepines*/toxicity; Humans

  • Source: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2024 Mar; Vol. 148, pp. 105570. Date of Electronic Publication: 2024 Jan 27.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8214983 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Synthesis and molecular docking simulations of novel azepines based on quinazolinone moiety as prospective antimicrobial and antitumor hedgehog signaling inhibitors.

  • Authors : Noser AA; Organic Chemistry, Chemistry Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt. .; El-Barbary AA

Subjects: Oxazepines*/Oxazepines*/Oxazepines*/pharmacology ; Anti-Infective Agents*/Anti-Infective Agents*/Anti-Infective Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry

  • Source: Scientific reports [Sci Rep] 2024 Feb 12; Vol. 14 (1), pp. 3530. Date of Electronic Publication: 2024 Feb 12.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Treatment of Sleep, Motor and Sensory Symptoms with the Orexin Antagonist Suvorexant in Adults with Idiopathic Restless Legs Syndrome: A Randomized Double-Blind Crossover Proof-of-Concept Study.

Subjects: Restless Legs Syndrome*/Restless Legs Syndrome*/Restless Legs Syndrome*/drug therapy ; Azepines* ; Triazoles*

  • Source: CNS drugs [CNS Drugs] 2024 Jan; Vol. 38 (1), pp. 45-54. Date of Electronic Publication: 2024 Jan 21.Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9431220 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Failure of the dual orexin receptor antagonist suvorexant to engender drug discrimination in rats.

Subjects: Orexin Receptor Antagonists*/Orexin Receptor Antagonists*/Orexin Receptor Antagonists*/pharmacology ; Azepines*/Azepines*/Azepines*/pharmacology; Humans

  • Source: Journal of psychopharmacology (Oxford, England) [J Psychopharmacol] 2023 Dec; Vol. 37 (12), pp. 1261-1264. Date of Electronic Publication: 2023 Nov 20.Publisher: Sage Publications Country of Publication: United States NLM ID: 8907828 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Organocatalytic Asymmetric Synthesis of Bridged Tetrahydrobenzo[ b ]azepines/oxepines.

  • Authors : Zou J; School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 400044, China.; Xu L

Subjects: Azepines*; Catalysis ; Molecular Structure

  • Source: Organic letters [Org Lett] 2022 Oct 07; Vol. 24 (39), pp. 7140-7144. Date of Electronic Publication: 2022 Sep 28.Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Diastereoselective Alkylations of Chiral Tetrazolo[1,5- a ]azepines via Heterobenzylic Anion Intermediates.

  • Authors : Witt CH; Department of Chemistry, New York University, 100 Washington Square East, New York, New York 10003, United States.; Woerpel KA

Subjects: Amines* ; Azepines*; Alkylation

  • Source: Organic letters [Org Lett] 2022 Sep 23; Vol. 24 (37), pp. 6722-6727. Date of Electronic Publication: 2022 Sep 12.Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  16,004 results for ""Azepines""